FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2766306160> ?p ?o ?g. }

• W2766306160 endingPage "5883" @default.
• W2766306160 startingPage "5880" @default.
• W2766306160 abstract "A practical and asymmetric synthesis of a functionalized trans-cyclopropoxy building block for the preparation of the HCV NS3/4a protease inhibitor grazoprevir is reported. Intramolecular SN2 displacement–ring closure, followed by a Baeyer–Villiger oxidation, yields the desired trans-cyclopropanol with full control of diastereoselectivity. A terminal alkyne is then effectively installed using LiNH(CH2)2NEt2. Starting from (S)-epichlorohydrin, the cyclopropoxy building block is prepared in 51% overall yield with >99.8% optical purity without isolation of any intermediates." @default.
• W2766306160 created "2017-11-10" @default.
• W2766306160 creator A5004892124 @default.
• W2766306160 creator A5005676210 @default.
• W2766306160 creator A5005766874 @default.
• W2766306160 creator A5006621039 @default.
• W2766306160 creator A5008420002 @default.
• W2766306160 creator A5032451259 @default.
• W2766306160 creator A5043042268 @default.
• W2766306160 creator A5055686536 @default.
• W2766306160 creator A5058619679 @default.
• W2766306160 creator A5084562339 @default.
• W2766306160 creator A5085142676 @default.
• W2766306160 date "2017-10-20" @default.
• W2766306160 modified "2023-10-17" @default.
• W2766306160 title "Asymmetric Synthesis of Functionalized <i>trans-</i>Cyclopropoxy Building Block for Grazoprevir" @default.
• W2766306160 cites W1964284609 @default.
• W2766306160 cites W1970469033 @default.
• W2766306160 cites W1982328669 @default.
• W2766306160 cites W1988968639 @default.
• W2766306160 cites W2000157693 @default.
• W2766306160 cites W2006732724 @default.
• W2766306160 cites W2007464831 @default.
• W2766306160 cites W2015645830 @default.
• W2766306160 cites W2023094594 @default.
• W2766306160 cites W2023898505 @default.
• W2766306160 cites W2040873242 @default.
• W2766306160 cites W2045251019 @default.
• W2766306160 cites W2047319800 @default.
• W2766306160 cites W2048169826 @default.
• W2766306160 cites W2058694265 @default.
• W2766306160 cites W2067469232 @default.
• W2766306160 cites W2079903599 @default.
• W2766306160 cites W2080696565 @default.
• W2766306160 cites W2091800127 @default.
• W2766306160 cites W2128134271 @default.
• W2766306160 cites W2169535828 @default.
• W2766306160 cites W2318090527 @default.
• W2766306160 cites W2325438237 @default.
• W2766306160 cites W2405677157 @default.
• W2766306160 cites W2518759502 @default.
• W2766306160 cites W2568365951 @default.
• W2766306160 cites W2572723913 @default.
• W2766306160 cites W2950247426 @default.
• W2766306160 cites W2950621140 @default.
• W2766306160 cites W2952789684 @default.
• W2766306160 cites W2952918862 @default.
• W2766306160 cites W4213242036 @default.
• W2766306160 cites W4323517670 @default.
• W2766306160 doi "https://doi.org/10.1021/acs.orglett.7b02867" @default.
• W2766306160 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29052413" @default.
• W2766306160 hasPublicationYear "2017" @default.
• W2766306160 type Work @default.
• W2766306160 sameAs 2766306160 @default.
• W2766306160 citedByCount "21" @default.
• W2766306160 countsByYear W27663061602017 @default.
• W2766306160 countsByYear W27663061602018 @default.
• W2766306160 countsByYear W27663061602019 @default.
• W2766306160 countsByYear W27663061602020 @default.
• W2766306160 countsByYear W27663061602022 @default.
• W2766306160 crossrefType "journal-article" @default.
• W2766306160 hasAuthorship W2766306160A5004892124 @default.
• W2766306160 hasAuthorship W2766306160A5005676210 @default.
• W2766306160 hasAuthorship W2766306160A5005766874 @default.
• W2766306160 hasAuthorship W2766306160A5006621039 @default.
• W2766306160 hasAuthorship W2766306160A5008420002 @default.
• W2766306160 hasAuthorship W2766306160A5032451259 @default.
• W2766306160 hasAuthorship W2766306160A5043042268 @default.
• W2766306160 hasAuthorship W2766306160A5055686536 @default.
• W2766306160 hasAuthorship W2766306160A5058619679 @default.
• W2766306160 hasAuthorship W2766306160A5084562339 @default.
• W2766306160 hasAuthorship W2766306160A5085142676 @default.
• W2766306160 hasConcept C134121241 @default.
• W2766306160 hasConcept C146686406 @default.
• W2766306160 hasConcept C161790260 @default.
• W2766306160 hasConcept C178790620 @default.
• W2766306160 hasConcept C185592680 @default.
• W2766306160 hasConcept C191897082 @default.
• W2766306160 hasConcept C192562407 @default.
• W2766306160 hasConcept C21951064 @default.
• W2766306160 hasConcept C2524010 @default.
• W2766306160 hasConcept C2777210771 @default.
• W2766306160 hasConcept C2779012754 @default.
• W2766306160 hasConcept C2780378348 @default.
• W2766306160 hasConcept C33923547 @default.
• W2766306160 hasConcept C71240020 @default.
• W2766306160 hasConcept C75079739 @default.
• W2766306160 hasConceptScore W2766306160C134121241 @default.
• W2766306160 hasConceptScore W2766306160C146686406 @default.
• W2766306160 hasConceptScore W2766306160C161790260 @default.
• W2766306160 hasConceptScore W2766306160C178790620 @default.
• W2766306160 hasConceptScore W2766306160C185592680 @default.
• W2766306160 hasConceptScore W2766306160C191897082 @default.
• W2766306160 hasConceptScore W2766306160C192562407 @default.
• W2766306160 hasConceptScore W2766306160C21951064 @default.
• W2766306160 hasConceptScore W2766306160C2524010 @default.
• W2766306160 hasConceptScore W2766306160C2777210771 @default.
• W2766306160 hasConceptScore W2766306160C2779012754 @default.

• next