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- W2766404600 abstract "The multiscale model of hepatitis C virus (HCV) dynamics, which includes intracellular viral RNA (vRNA) replication, has been formulated in recent years in order to provide a new conceptual framework for understanding the mechanism of action of a variety of agents for the treatment of HCV. We present a robust and efficient numerical method that belongs to the family of adaptive stepsize methods and is implicit, a Rosenbrock type method that is highly suited to solve this problem. We provide a Graphical User Interface that applies this method and is useful for simulating viral dynamics during treatment with anti-HCV agents that act against HCV on the molecular level." @default.
- W2766404600 created "2017-11-10" @default.
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- W2766404600 date "2017-10-31" @default.
- W2766404600 modified "2023-09-24" @default.
- W2766404600 title "A Robust and Efficient Numerical Method for RNA-Mediated Viral Dynamics" @default.
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- W2766404600 doi "https://doi.org/10.3389/fams.2017.00020" @default.
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