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- W2766454055 abstract "Burning sensation at the site of application is the most common side effect of topical calcineurin inhibitors and is considered the most common reasons for premature discontinuation. Here, we analyze the possible mechanism(s) and offer a simple practical tip to mitigate this adverse effect. Simple cooling of the tube, immediately before use, does reduce the burning sensation and enable most intolerant patients to use the medication comfortably. We also discuss the possible explanation(s) for the success of this maneuver." @default.
- W2766454055 created "2017-11-10" @default.
- W2766454055 creator A5013136080 @default.
- W2766454055 date "2010-04-01" @default.
- W2766454055 modified "2023-10-13" @default.
- W2766454055 title "Practical tip: Precooling topical calcineurin inhibitors tube; reduces burning sensation" @default.
- W2766454055 doi "https://doi.org/10.5070/d31s72g865" @default.
- W2766454055 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20409423" @default.
- W2766454055 hasPublicationYear "2010" @default.
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