FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2766506711> ?p ?o ?g. }

• W2766506711 endingPage "649" @default.
• W2766506711 startingPage "642" @default.
• W2766506711 abstract "Bacillus subtilis is widely used as cell factories for the production of important industrial biochemicals. Although many studies have demonstrated the effects of organic acidic byproducts, such as acetate, on microbial fermentation, little is known about the effects of blocking the neutral byproduct overflow, such as acetoin, on bioproduction. In this study, we focused on the influences of modulating overflow metabolism on the production of N-acetyl-d-glucosamine (GlcNAc) in engineered B. subtilis. We found that acetoin overflow competes with GlcNAc production, and blocking acetoin overflow increased GlcNAc titer and yield by 1.38- and 1.39-fold, reaching 48.9 g/L and 0.32 g GlcNAc/g glucose, respectively. Further blocking acetate overflow inhibited cell growth and GlcNAc production may be induced by inhibiting glucose uptake. Taken together, our results show that blocking acetoin overflow is a promising strategy for enhancing GlcNAc production. The strategies developed in this work may be useful for engineering strains of B. subtilis for producing other important biochemicals." @default.
• W2766506711 created "2017-11-10" @default.
• W2766506711 creator A5004433515 @default.
• W2766506711 creator A5019397177 @default.
• W2766506711 creator A5050092994 @default.
• W2766506711 creator A5053438728 @default.
• W2766506711 creator A5063920010 @default.
• W2766506711 creator A5067843915 @default.
• W2766506711 creator A5070760163 @default.
• W2766506711 date "2018-02-01" @default.
• W2766506711 modified "2023-10-15" @default.
• W2766506711 title "Metabolic engineering of carbon overflow metabolism of Bacillus subtilis for improved N-acetyl-glucosamine production" @default.
• W2766506711 cites W1677985623 @default.
• W2766506711 cites W1730175586 @default.
• W2766506711 cites W1971185610 @default.
• W2766506711 cites W1973180388 @default.
• W2766506711 cites W1975097455 @default.
• W2766506711 cites W1987746186 @default.
• W2766506711 cites W1990834279 @default.
• W2766506711 cites W1995786397 @default.
• W2766506711 cites W2001576536 @default.
• W2766506711 cites W2009560463 @default.
• W2766506711 cites W2011893021 @default.
• W2766506711 cites W2022381548 @default.
• W2766506711 cites W2028927478 @default.
• W2766506711 cites W2032926938 @default.
• W2766506711 cites W2033053563 @default.
• W2766506711 cites W2034763308 @default.
• W2766506711 cites W2045377520 @default.
• W2766506711 cites W2071674796 @default.
• W2766506711 cites W2074294917 @default.
• W2766506711 cites W2086031314 @default.
• W2766506711 cites W2092339982 @default.
• W2766506711 cites W2096604031 @default.
• W2766506711 cites W2106747743 @default.
• W2766506711 cites W2121530190 @default.
• W2766506711 cites W2147232469 @default.
• W2766506711 cites W2156661254 @default.
• W2766506711 cites W2161497170 @default.
• W2766506711 cites W2161539653 @default.
• W2766506711 cites W2171746101 @default.
• W2766506711 cites W2197016826 @default.
• W2766506711 cites W2238344000 @default.
• W2766506711 cites W2301068496 @default.
• W2766506711 cites W2416065856 @default.
• W2766506711 cites W2518333253 @default.
• W2766506711 cites W2545368672 @default.
• W2766506711 cites W2588939280 @default.
• W2766506711 cites W2606699224 @default.
• W2766506711 cites W2613007680 @default.
• W2766506711 doi "https://doi.org/10.1016/j.biortech.2017.10.007" @default.
• W2766506711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29220808" @default.
• W2766506711 hasPublicationYear "2018" @default.
• W2766506711 type Work @default.
• W2766506711 sameAs 2766506711 @default.
• W2766506711 citedByCount "41" @default.
• W2766506711 countsByYear W27665067112018 @default.
• W2766506711 countsByYear W27665067112019 @default.
• W2766506711 countsByYear W27665067112020 @default.
• W2766506711 countsByYear W27665067112021 @default.
• W2766506711 countsByYear W27665067112022 @default.
• W2766506711 countsByYear W27665067112023 @default.
• W2766506711 crossrefType "journal-article" @default.
• W2766506711 hasAuthorship W2766506711A5004433515 @default.
• W2766506711 hasAuthorship W2766506711A5019397177 @default.
• W2766506711 hasAuthorship W2766506711A5050092994 @default.
• W2766506711 hasAuthorship W2766506711A5053438728 @default.
• W2766506711 hasAuthorship W2766506711A5063920010 @default.
• W2766506711 hasAuthorship W2766506711A5067843915 @default.
• W2766506711 hasAuthorship W2766506711A5070760163 @default.
• W2766506711 hasConcept C100544194 @default.
• W2766506711 hasConcept C181199279 @default.
• W2766506711 hasConcept C185592680 @default.
• W2766506711 hasConcept C2777272437 @default.
• W2766506711 hasConcept C2777937268 @default.
• W2766506711 hasConcept C2779227428 @default.
• W2766506711 hasConcept C523546767 @default.
• W2766506711 hasConcept C54355233 @default.
• W2766506711 hasConcept C55493867 @default.
• W2766506711 hasConcept C6350086 @default.
• W2766506711 hasConcept C86803240 @default.
• W2766506711 hasConceptScore W2766506711C100544194 @default.
• W2766506711 hasConceptScore W2766506711C181199279 @default.
• W2766506711 hasConceptScore W2766506711C185592680 @default.
• W2766506711 hasConceptScore W2766506711C2777272437 @default.
• W2766506711 hasConceptScore W2766506711C2777937268 @default.
• W2766506711 hasConceptScore W2766506711C2779227428 @default.
• W2766506711 hasConceptScore W2766506711C523546767 @default.
• W2766506711 hasConceptScore W2766506711C54355233 @default.
• W2766506711 hasConceptScore W2766506711C55493867 @default.
• W2766506711 hasConceptScore W2766506711C6350086 @default.
• W2766506711 hasConceptScore W2766506711C86803240 @default.
• W2766506711 hasFunder F4320321001 @default.
• W2766506711 hasFunder F4320321543 @default.
• W2766506711 hasFunder F4320322769 @default.
• W2766506711 hasFunder F4320335787 @default.
• W2766506711 hasLocation W27665067111 @default.
• W2766506711 hasLocation W27665067112 @default.

• next