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- W2766697748 abstract "Esophagus stents are a common and effective treatment for esophageal strictures. Esophageal stricture can cause dysphagia, weight loss, malnutrition, respiratory failure and aspiration. Limitations of current self-expanding metal and plastic stents include ingrowth of tissue and stent restenosis. Partially covered self-expanding metal stents (SEMS) tend to become embedded in tissue and difficult to remove. Self-expanding plastic stents (SEPS) as well as fully covered SEMS have a high migration rate. The major benefit of polymeric biodegradable stents (BDS) is that do not require to be removed as a result of decomposition into non-toxic chemical species. Patient concerns regarding implant permanence in addition to long-term risks like thrombosis are reduced. Furthermore, BDSs are able to carry and release drugs as they degrade. Limitations of these devices are the mechanical strength and lower radial force that diminish effectiveness of the stent in stricture dilation and leak closure. This chapter reviews recent clinical evidence of BDS." @default.
- W2766697748 created "2017-11-10" @default.
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- W2766697748 date "2017-01-01" @default.
- W2766697748 modified "2023-10-17" @default.
- W2766697748 title "Biodegradable Polymeric Esophagus Stents" @default.
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- W2766697748 doi "https://doi.org/10.1021/bk-2017-1253.ch012" @default.
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