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- W2766707981 abstract "A new fatty acid ester (1) and seven known phenolic compounds, i.e. salfredin B11 (2), nigephenol C (3), nigephenol B (4), acetovanillion (5), p-hydroxybenzoic acid (6), p-hydroxy-acetophenone (7) and p-hydroxybenzaldehyde (8), were isolated from the seeds of Nigella sativa var. hispidula. Among them, compounds 5, 7 and 8 were isolated from Nigella for the first time. Their structures were elucidated with HR-ESI-MS, 1D and 2D NMR spectra. Evaluation of the isolated compounds on protein tyrosine phosphatase (PTP1B) assay indicated that although compounds 2–8 show no promising anti-PTP1B activities, compound 1 possess anti-PTP1B activity with an IC50 value of 7.38 ± 0.14 μM in vitro." @default.
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- W2766707981 date "2017-10-31" @default.
- W2766707981 modified "2023-10-15" @default.
- W2766707981 title "A new fatty acid ester from <i>Nigella sativa</i> var. <i>hispidula</i> Boiss showing potent anti-protein tyrosine phosphatase 1B activity" @default.
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- W2766707981 doi "https://doi.org/10.1080/14786419.2017.1396594" @default.
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