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- W2767029983 abstract "The freshwater climbing perch, Anabas testudineus, is an euryhaline teleost and an obligate air-breather with the ability to actively excrete ammonia. Members of the Na+/H+ exchanger (NHE) family help maintain intracellular pH homeostasis and ionic balance through the electroneutral exchange of Na+ and H+. This study aimed to obtain, from the gills of A. testudineus, the full cDNA coding sequence of nhe3, and to determine the effects of exposure to seawater or 100 mmol l-1 of NH4Cl in fresh water on its mRNA and protein expression levels. Efforts were also made to elucidate the type of ionocyte that Nhe3 was associated with in the branchial epithelium of A. testudineus. The transcript level and protein abundance of nhe3/Nhe3 were very low in the gills of freshwater A. testudineus, but they increased significantly in the gills of fish acclimated to seawater. In the gills of fish exposed to seawater, Nhe3 was expressed in two distinct types of seawater-inducible Na+/K+-ATPase (Nka)-immunoreactive ionocytes. In Nkaα1b-immunoreactive ionocytes, Nhe3 had an apical localization. As these ionocytes also expressed apical Rhcg1 and basolateral Rhcg2, which are known to transport ammonia, they probably participated in proton-facilitated ammonia excretion in A. testudineus during seawater acclimation. In Nkaα1c-immunoreactive ionocytes, Nhe3 was atypically expressed in the basolateral membrane, and its physiological function is uncertain. For A. testudineus exposed to NH4Cl in fresh water, the transcript and protein expression levels of nhe3/Nhe3 remained low. In conclusion, the branchial Nhe3 of A. testudineus plays a greater physiological role in passive ammonia transport and acid-base balance during seawater acclimation than in active ammonia excretion during environmental ammonia exposure." @default.
- W2767029983 created "2017-11-10" @default.
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- W2767029983 date "2017-11-02" @default.
- W2767029983 modified "2023-10-18" @default.
- W2767029983 title "Na+/H+ Exchanger 3 Is Expressed in Two Distinct Types of Ionocyte, and Probably Augments Ammonia Excretion in One of Them, in the Gills of the Climbing Perch Exposed to Seawater" @default.
- W2767029983 cites W1489447720 @default.
- W2767029983 cites W1597762675 @default.
- W2767029983 cites W1913357042 @default.
- W2767029983 cites W1935523782 @default.
- W2767029983 cites W1966161978 @default.
- W2767029983 cites W1968497770 @default.
- W2767029983 cites W1984415378 @default.
- W2767029983 cites W1988186522 @default.
- W2767029983 cites W1989498801 @default.
- W2767029983 cites W1991000739 @default.
- W2767029983 cites W1996422650 @default.
- W2767029983 cites W2008651235 @default.
- W2767029983 cites W2009755318 @default.
- W2767029983 cites W2013354167 @default.
- W2767029983 cites W2015079235 @default.
- W2767029983 cites W2018289835 @default.
- W2767029983 cites W2018394886 @default.
- W2767029983 cites W2031489816 @default.
- W2767029983 cites W2034224320 @default.
- W2767029983 cites W2039031569 @default.
- W2767029983 cites W2040464218 @default.
- W2767029983 cites W2046766513 @default.
- W2767029983 cites W2061842840 @default.
- W2767029983 cites W2063969340 @default.
- W2767029983 cites W2066504529 @default.
- W2767029983 cites W2069939390 @default.
- W2767029983 cites W2073411380 @default.
- W2767029983 cites W2078965780 @default.
- W2767029983 cites W2087784543 @default.
- W2767029983 cites W2088245876 @default.
- W2767029983 cites W2088749301 @default.
- W2767029983 cites W2090826863 @default.
- W2767029983 cites W2096113253 @default.
- W2767029983 cites W2096246094 @default.
- W2767029983 cites W2100293940 @default.
- W2767029983 cites W2100837269 @default.
- W2767029983 cites W2109724077 @default.
- W2767029983 cites W2111129563 @default.
- W2767029983 cites W2112949737 @default.
- W2767029983 cites W2115629412 @default.
- W2767029983 cites W2119206554 @default.
- W2767029983 cites W2120002311 @default.
- W2767029983 cites W2121170987 @default.
- W2767029983 cites W2121736800 @default.
- W2767029983 cites W2124177023 @default.
- W2767029983 cites W2124285177 @default.
- W2767029983 cites W2127484064 @default.
- W2767029983 cites W2128330828 @default.
- W2767029983 cites W2128635872 @default.
- W2767029983 cites W2131683054 @default.
- W2767029983 cites W2133586454 @default.
- W2767029983 cites W2136418324 @default.
- W2767029983 cites W2138601751 @default.
- W2767029983 cites W2141088513 @default.
- W2767029983 cites W2150081094 @default.
- W2767029983 cites W2152534793 @default.
- W2767029983 cites W2156935972 @default.
- W2767029983 cites W2163373683 @default.
- W2767029983 cites W2165743932 @default.
- W2767029983 cites W2166748672 @default.
- W2767029983 cites W2169749000 @default.
- W2767029983 cites W2172748577 @default.
- W2767029983 cites W2187771246 @default.
- W2767029983 cites W2272423367 @default.
- W2767029983 cites W2396092200 @default.
- W2767029983 cites W2408040700 @default.
- W2767029983 cites W2489450420 @default.
- W2767029983 cites W2508083522 @default.
- W2767029983 cites W2620813957 @default.
- W2767029983 cites W2941423948 @default.
- W2767029983 cites W4293247451 @default.
- W2767029983 doi "https://doi.org/10.3389/fphys.2017.00880" @default.
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- W2767029983 hasPublicationYear "2017" @default.
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