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- W2767053399 abstract "Osteosarcoma (OSA) is a rare cancer in people. However OSA incidence rates in dogs are 27 times higher than in people. Prognosis in both species is relatively poor, with 5 year OSA survival rates in people not having improved in decades. For dogs, 1 year survival rates are only around ~ 45%. Improved and novel treatment regimens are urgently required to improve survival in both humans and dogs with OSA. Utilising information from genetic studies could assist in this in both species, with the higher incidence rates in dogs contributing to the dog population being a good model of human disease. This review compares the clinical characteristics, gross morphology and histopathology, aetiology, epidemiology, and genetics of canine and human OSA. Finally, the current position of canine OSA genetic research is discussed and areas for additional work within the canine population are identified." @default.
- W2767053399 created "2017-11-10" @default.
- W2767053399 creator A5028477382 @default.
- W2767053399 creator A5037178720 @default.
- W2767053399 creator A5043200316 @default.
- W2767053399 creator A5066413879 @default.
- W2767053399 creator A5067879551 @default.
- W2767053399 creator A5091320190 @default.
- W2767053399 date "2017-10-24" @default.
- W2767053399 modified "2023-10-18" @default.
- W2767053399 title "Comparative review of human and canine osteosarcoma: morphology, epidemiology, prognosis, treatment and genetics" @default.
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