FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767079449> ?p ?o ?g. }

• W2767079449 endingPage "2339" @default.
• W2767079449 startingPage "2339" @default.
• W2767079449 abstract "To increase the overall survival rate and obtain a better prognosis for oral squamous cell carcinoma (OSCC) patients, the detection of more effective and reliable tumor prognostic markers is needed. This study is focused on the analysis of correlation between the clinicopathological features of OSCCs and the immunohistochemical (IHC) expression patterns of MIDKINE (MK) and NANOG. Sixty-two primary OSCC patients were selected and their pretreatment biopsy specimens were immunohistochemically analyzed for the MK and NANOG proteins. The IHC expression patterns, clinicopathological features, and overall survival rates were assessed to identify any correlations. MK and NANOG showed significantly similar IHC expression patterns: both demonstrated enhanced expression in histologically high-grade and clinically late-stage OSCCs. Weak or negative expression of MK and NANOG was correlated with negative neck node metastasis. Clinicopathologically, late tumor stage, neck node metastasis, high-grade tumor, and palliative treatment groups showed significantly lower overall survival rates. The enhanced expression of MK and NANOG was associated with lower overall survival rates. In particular, enhanced co-detection of MK and NANOG showed significant correlation with poor prognosis. In conclusion, enhanced IHC expression patterns of MK and NANOG in OSCC patients was significantly associated with lower overall survival rates and unfavorable clinicopathological features. These results demonstrate that analysis of IHC expression patterns of MK and NANOG in pretreatment biopsy specimens during the work-up period can provide a more definitive prognosis prediction for each OSCC patient that can help clinicians to develop a more precise individual treatment modality." @default.
• W2767079449 created "2017-11-10" @default.
• W2767079449 creator A5001652670 @default.
• W2767079449 creator A5001684645 @default.
• W2767079449 creator A5027717102 @default.
• W2767079449 creator A5030549439 @default.
• W2767079449 creator A5050239697 @default.
• W2767079449 creator A5054365406 @default.
• W2767079449 creator A5057152891 @default.
• W2767079449 date "2017-11-06" @default.
• W2767079449 modified "2023-10-17" @default.
• W2767079449 title "Midkine and NANOG Have Similar Immunohistochemical Expression Patterns and Contribute Equally to an Adverse Prognosis of Oral Squamous Cell Carcinoma" @default.
• W2767079449 cites W1540459150 @default.
• W2767079449 cites W1734170005 @default.
• W2767079449 cites W1868370380 @default.
• W2767079449 cites W1900166471 @default.
• W2767079449 cites W1951715837 @default.
• W2767079449 cites W1971158626 @default.
• W2767079449 cites W1982580620 @default.
• W2767079449 cites W1993097520 @default.
• W2767079449 cites W2016081624 @default.
• W2767079449 cites W2028801216 @default.
• W2767079449 cites W2042547587 @default.
• W2767079449 cites W2051493007 @default.
• W2767079449 cites W2067693899 @default.
• W2767079449 cites W2070038950 @default.
• W2767079449 cites W2077175035 @default.
• W2767079449 cites W2079196221 @default.
• W2767079449 cites W2092897175 @default.
• W2767079449 cites W2093974096 @default.
• W2767079449 cites W2098877138 @default.
• W2767079449 cites W2110079994 @default.
• W2767079449 cites W2124029327 @default.
• W2767079449 cites W2124593264 @default.
• W2767079449 cites W2145761648 @default.
• W2767079449 cites W2150289099 @default.
• W2767079449 cites W2156007002 @default.
• W2767079449 cites W2156336275 @default.
• W2767079449 cites W2166110347 @default.
• W2767079449 cites W2170085261 @default.
• W2767079449 cites W2171900792 @default.
• W2767079449 cites W2184087924 @default.
• W2767079449 cites W2589703425 @default.
• W2767079449 cites W2620894078 @default.
• W2767079449 doi "https://doi.org/10.3390/ijms18112339" @default.
• W2767079449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5713308" @default.
• W2767079449 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29113102" @default.
• W2767079449 hasPublicationYear "2017" @default.
• W2767079449 type Work @default.
• W2767079449 sameAs 2767079449 @default.
• W2767079449 citedByCount "14" @default.
• W2767079449 countsByYear W27670794492018 @default.
• W2767079449 countsByYear W27670794492019 @default.
• W2767079449 countsByYear W27670794492020 @default.
• W2767079449 countsByYear W27670794492021 @default.
• W2767079449 countsByYear W27670794492022 @default.
• W2767079449 crossrefType "journal-article" @default.
• W2767079449 hasAuthorship W2767079449A5001652670 @default.
• W2767079449 hasAuthorship W2767079449A5001684645 @default.
• W2767079449 hasAuthorship W2767079449A5027717102 @default.
• W2767079449 hasAuthorship W2767079449A5030549439 @default.
• W2767079449 hasAuthorship W2767079449A5050239697 @default.
• W2767079449 hasAuthorship W2767079449A5054365406 @default.
• W2767079449 hasAuthorship W2767079449A5057152891 @default.
• W2767079449 hasBestOaLocation W27670794491 @default.
• W2767079449 hasConcept C104317684 @default.
• W2767079449 hasConcept C107459253 @default.
• W2767079449 hasConcept C121608353 @default.
• W2767079449 hasConcept C126322002 @default.
• W2767079449 hasConcept C142724271 @default.
• W2767079449 hasConcept C143998085 @default.
• W2767079449 hasConcept C145103041 @default.
• W2767079449 hasConcept C158074577 @default.
• W2767079449 hasConcept C170493617 @default.
• W2767079449 hasConcept C204232928 @default.
• W2767079449 hasConcept C207701140 @default.
• W2767079449 hasConcept C2775934546 @default.
• W2767079449 hasConcept C2775960820 @default.
• W2767079449 hasConcept C2779013556 @default.
• W2767079449 hasConcept C502942594 @default.
• W2767079449 hasConcept C55493867 @default.
• W2767079449 hasConcept C71924100 @default.
• W2767079449 hasConcept C86803240 @default.
• W2767079449 hasConceptScore W2767079449C104317684 @default.
• W2767079449 hasConceptScore W2767079449C107459253 @default.
• W2767079449 hasConceptScore W2767079449C121608353 @default.
• W2767079449 hasConceptScore W2767079449C126322002 @default.
• W2767079449 hasConceptScore W2767079449C142724271 @default.
• W2767079449 hasConceptScore W2767079449C143998085 @default.
• W2767079449 hasConceptScore W2767079449C145103041 @default.
• W2767079449 hasConceptScore W2767079449C158074577 @default.
• W2767079449 hasConceptScore W2767079449C170493617 @default.
• W2767079449 hasConceptScore W2767079449C204232928 @default.
• W2767079449 hasConceptScore W2767079449C207701140 @default.
• W2767079449 hasConceptScore W2767079449C2775934546 @default.
• W2767079449 hasConceptScore W2767079449C2775960820 @default.
• W2767079449 hasConceptScore W2767079449C2779013556 @default.
• W2767079449 hasConceptScore W2767079449C502942594 @default.

• next