FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767148924> ?p ?o ?g. }

• W2767148924 endingPage "3530" @default.
• W2767148924 startingPage "3522" @default.
• W2767148924 abstract "Background: Breast cancer (BC)-derived hyaluronan (HA) can induce the formation of M2-like tumor-associated macrophages (TAMs) in tumor context. However, little is known about the correlation between circulating M2-like monocytes and plasma HA in BC patients. This study focused on evaluating the relationship between circulating M2-like monocytes and plasma HA, and further appraised the diagnostic value of them in BC. Methods: The expression of M2-like TAMs and HA was determined in pathological tissues by immunohistochemistry. Flow cytometry was used to detect the levels of circulating CD14+CD204+ M2-like monocytes in 81 BC patients, 45 patients with breast benign diseases, and 46 healthy subjects. The levels of HA, CEA, and CA15-3 were measured in plasma samples using chemiluminescence method. Results: M2-like TAMs and HA expressions were elevated in BC tissues compared with benign tissues. In correspondence, the frequency of circulating CD14+CD204+ M2-like monocytes and the plasma HA levels were significantly higher in patients with BC than those in control groups. Importantly, there was a positive correlation between circulating M2-like monocytes and the plasma HA (Spearman r = 0.404, p < 0.001). Area under receiver operating characteristic curve (ROC) for the combination of circulating M2-like monocytes and HA was 0.899 (95% CI: 0.853-0.946), which was higher than the panel of CEA and CA15-3. Conclusions: The frequency of circulating CD14+CD204+ M2-like monocytes was positively correlated to plasma HA levels. The combination of circulating CD14+CD204+ M2-like monocytes and plasma HA could provide considerable diagnostic value in BC." @default.
• W2767148924 created "2017-11-10" @default.
• W2767148924 creator A5003852242 @default.
• W2767148924 creator A5028948838 @default.
• W2767148924 creator A5030419296 @default.
• W2767148924 creator A5031369364 @default.
• W2767148924 creator A5036189659 @default.
• W2767148924 creator A5053528169 @default.
• W2767148924 creator A5071758354 @default.
• W2767148924 creator A5074391954 @default.
• W2767148924 creator A5080135418 @default.
• W2767148924 creator A5084266744 @default.
• W2767148924 date "2017-01-01" @default.
• W2767148924 modified "2023-10-01" @default.
• W2767148924 title "Combination of plasma HA and circulating M2-like monocytes may serve as a diagnostic marker for breast cancer" @default.
• W2767148924 cites W1598422965 @default.
• W2767148924 cites W1891380900 @default.
• W2767148924 cites W1892496998 @default.
• W2767148924 cites W1919137762 @default.
• W2767148924 cites W1919685122 @default.
• W2767148924 cites W2000688089 @default.
• W2767148924 cites W2001717792 @default.
• W2767148924 cites W2010480948 @default.
• W2767148924 cites W2014535644 @default.
• W2767148924 cites W2020210694 @default.
• W2767148924 cites W2037489902 @default.
• W2767148924 cites W2053059448 @default.
• W2767148924 cites W2058631111 @default.
• W2767148924 cites W2080860848 @default.
• W2767148924 cites W2089573422 @default.
• W2767148924 cites W2124846832 @default.
• W2767148924 cites W2127714324 @default.
• W2767148924 cites W2136806837 @default.
• W2767148924 cites W2137967850 @default.
• W2767148924 cites W2154674858 @default.
• W2767148924 cites W2157394658 @default.
• W2767148924 cites W2158432454 @default.
• W2767148924 cites W2170368666 @default.
• W2767148924 cites W2170481258 @default.
• W2767148924 cites W2199099822 @default.
• W2767148924 cites W2272984102 @default.
• W2767148924 cites W2343597033 @default.
• W2767148924 cites W2476542314 @default.
• W2767148924 doi "https://doi.org/10.7150/jca.20227" @default.
• W2767148924 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5687167" @default.
• W2767148924 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29151937" @default.
• W2767148924 hasPublicationYear "2017" @default.
• W2767148924 type Work @default.
• W2767148924 sameAs 2767148924 @default.
• W2767148924 citedByCount "4" @default.
• W2767148924 countsByYear W27671489242019 @default.
• W2767148924 countsByYear W27671489242020 @default.
• W2767148924 countsByYear W27671489242021 @default.
• W2767148924 countsByYear W27671489242022 @default.
• W2767148924 crossrefType "journal-article" @default.
• W2767148924 hasAuthorship W2767148924A5003852242 @default.
• W2767148924 hasAuthorship W2767148924A5028948838 @default.
• W2767148924 hasAuthorship W2767148924A5030419296 @default.
• W2767148924 hasAuthorship W2767148924A5031369364 @default.
• W2767148924 hasAuthorship W2767148924A5036189659 @default.
• W2767148924 hasAuthorship W2767148924A5053528169 @default.
• W2767148924 hasAuthorship W2767148924A5071758354 @default.
• W2767148924 hasAuthorship W2767148924A5074391954 @default.
• W2767148924 hasAuthorship W2767148924A5080135418 @default.
• W2767148924 hasAuthorship W2767148924A5084266744 @default.
• W2767148924 hasBestOaLocation W27671489241 @default.
• W2767148924 hasConcept C121608353 @default.
• W2767148924 hasConcept C126322002 @default.
• W2767148924 hasConcept C142724271 @default.
• W2767148924 hasConcept C151730666 @default.
• W2767148924 hasConcept C203014093 @default.
• W2767148924 hasConcept C2778513237 @default.
• W2767148924 hasConcept C2779343474 @default.
• W2767148924 hasConcept C2781184567 @default.
• W2767148924 hasConcept C530470458 @default.
• W2767148924 hasConcept C553184892 @default.
• W2767148924 hasConcept C71924100 @default.
• W2767148924 hasConcept C86803240 @default.
• W2767148924 hasConceptScore W2767148924C121608353 @default.
• W2767148924 hasConceptScore W2767148924C126322002 @default.
• W2767148924 hasConceptScore W2767148924C142724271 @default.
• W2767148924 hasConceptScore W2767148924C151730666 @default.
• W2767148924 hasConceptScore W2767148924C203014093 @default.
• W2767148924 hasConceptScore W2767148924C2778513237 @default.
• W2767148924 hasConceptScore W2767148924C2779343474 @default.
• W2767148924 hasConceptScore W2767148924C2781184567 @default.
• W2767148924 hasConceptScore W2767148924C530470458 @default.
• W2767148924 hasConceptScore W2767148924C553184892 @default.
• W2767148924 hasConceptScore W2767148924C71924100 @default.
• W2767148924 hasConceptScore W2767148924C86803240 @default.
• W2767148924 hasIssue "17" @default.
• W2767148924 hasLocation W27671489241 @default.
• W2767148924 hasLocation W27671489242 @default.
• W2767148924 hasLocation W27671489243 @default.
• W2767148924 hasLocation W27671489244 @default.
• W2767148924 hasOpenAccess W2767148924 @default.
• W2767148924 hasPrimaryLocation W27671489241 @default.
• W2767148924 hasRelatedWork W1584783298 @default.

• next