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- W2767172014 endingPage "249" @default.
- W2767172014 startingPage "249" @default.
- W2767172014 abstract "The disorders of gastrointestinal (GI) tract including intestine and colon are common in the patients with diabetes mellitus (DM). DM induced intestinal and colonic structural and biomechanical remodeling in animals and humans. The remodeling is closely related to motor-sensory abnormalities of the intestine and colon which are associated with the symptoms frequently encountered in patients with DM such as diarrhea and constipation. In this review, firstly we review DM-induced histomorphological and biomechanical remodeling of intestine and colon. Secondly we review motor-sensory dysfunction and how they relate to intestinal and colonic abnormalities. Finally the clinical consequences of DM-induced changes in the intestine and colon including diarrhea, constipation, gut microbiota change and colon cancer are discussed. The final goal is to increase the understanding of DM-induced changes in the gut and the subsequent clinical consequences in order to provide the clinicians with a better understanding of the GI disorders in diabetic patients and facilitates treatments tailored to these patients." @default.
- W2767172014 created "2017-11-10" @default.
- W2767172014 creator A5004311292 @default.
- W2767172014 creator A5014325215 @default.
- W2767172014 creator A5077415554 @default.
- W2767172014 date "2017-01-01" @default.
- W2767172014 modified "2023-10-11" @default.
- W2767172014 title "Diabetes-induced mechanophysiological changes in the small intestine and colon" @default.
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