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• W2767210005 abstract "Abstract Training and immobilization are powerful drivers of use-dependent plasticity in human primary motor hand area (M1 HAND ). Here we used transcranial magnetic stimulation to clarify how training and immobilisation of a single finger interact within M1 HAND . Healthy volunteers trained to track a moving target with a finger for one week. The tracking skill acquired with the trained finger was transferred to a non-trained finger of the same hand. The cortical representations of the trained and non-trained finger muscle converged in proportion with skill transfer. Finger immobilisation alone attenuated the corticomotor representation and pre-existing tracking skill of the immobilized finger. The detrimental effects of finger immobilization were blocked by concurrent training of the non-immobilized finger. Conversely, immobilization of the non-trained fingers accelerated learning during the first two days of training. The results provide novel insight into use-dependent cortical plasticity, revealing synergistic rather than competitive interaction patterns within M1 HAND ." @default.
• W2767210005 created "2017-11-17" @default.
• W2767210005 creator A5048696924 @default.
• W2767210005 creator A5070809930 @default.
• W2767210005 date "2017-11-10" @default.
• W2767210005 modified "2023-09-24" @default.
• W2767210005 title "Use-dependent plasticity in human primary motor hand area: Synergistic interplay between training and immobilisation" @default.
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• W2767210005 doi "https://doi.org/10.1101/217661" @default.
• W2767210005 hasPublicationYear "2017" @default.
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