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- W2767268116 abstract "Abstract A highly efficient and eco-friendly protocol has been described for the synthesis of amidomethylarenes and -heteroarenes via one-pot three-component coupling reaction of amides, aldehydes and (hetero)arenes over a heterogeneous catalyst (Hβ zeolite) in solvent-free conditions. The scope and limitations of this catalytic process are demonstrated with various amides and arenes and the corresponding amidoalkylated arene products were obtained in moderate to excellent yields. The preliminary mechanistic insight (control experiments) suggest that bisamide and/or N-(hydroxymethyl)benzamide are probable intermediates in this reaction. Moreover, the catalyst can be reused without any significant loss of the catalytic activity and only water is produced as by-product." @default.
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- W2767268116 date "2018-02-01" @default.
- W2767268116 modified "2023-09-24" @default.
- W2767268116 title "Three-component synthesis of amidomethylarenes and -heteroarenes over Hβ zeolite under solvent-free conditions" @default.
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- W2767268116 doi "https://doi.org/10.1016/j.catcom.2017.11.002" @default.
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