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• W2767326874 endingPage "20170490" @default.
• W2767326874 startingPage "20170490" @default.
• W2767326874 abstract "Adult gliomas are aggressive brain tumours associated with low patient survival rates and limited life expectancy. The most important hallmark of this type of tumour is its invasive behaviour, characterized by a markedly phenotypic plasticity, infiltrative tumour morphologies and the ability of malignant progression from low- to high-grade tumour types. Indeed, the widespread infiltration of healthy brain tissue by glioma cells is largely responsible for poor prognosis and the difficulty of finding curative therapies. Meanwhile, mathematical models have been established to analyse potential mechanisms of glioma invasion. In this review, we start with a brief introduction to current biological knowledge about glioma invasion, and then critically review and highlight future challenges for mathematical models of glioma invasion." @default.
• W2767326874 created "2017-11-17" @default.
• W2767326874 creator A5007775969 @default.
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• W2767326874 creator A5052721598 @default.
• W2767326874 creator A5081906909 @default.
• W2767326874 creator A5086242721 @default.
• W2767326874 date "2017-11-01" @default.
• W2767326874 modified "2023-10-14" @default.
• W2767326874 title "The biology and mathematical modelling of glioma invasion: a review" @default.
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