Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767474140> ?p ?o ?g. }
- W2767474140 endingPage "e8573" @default.
- W2767474140 startingPage "e8573" @default.
- W2767474140 abstract "This retrospective comparative study aims to explore the time courses of serum myoglobin (Mb) changes, and summarize our experience in treating patients with hypermyoglobinemia after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).This study covered 60 patients with peritoneal carcinomatosis treated with CRS + HIPEC as the study group, and another 25 cancer patients treated with conventional extensive surgery without HIPEC as the control group from February to October 2016. In the study group, patients with postoperative hypermyoglobinemia were on a comprehensive treatment regimen consisting intravenous injection of sodium bicarbonate solution according to the Mb level. In the control group, patients were recorded and treated with the same regimen except for special sodium bicarbonate solution. The preoperative and postoperative serum Mb, blood urine nitrogen (BUN), and creatinine (Cr) levels were evaluated.There were no significantly difference between the 2 groups in serum Mb, BUN, and Cr levels before surgery. Postoperative serum Mb levels were elevated in both groups and significantly higher on postoperative 0 to 2 days (P < .05) in the study group than the control group. The peak value of serum Mb levels (426.65 ± 108.386 μg/L) occurred on the surgery day. The serum Mb change rate was much bigger in the study group than the control group. Serum BUN levels in both groups revealed a slow increase during the early postoperative period and were significantly lower in the study group than the control group on days 1 and 2. The serum Cr levels were similar and stable between the 2 groups after surgery. The serum Cr change rates changed synchronously with same tendency in both groups, and on postoperative day 1 the increase rate was bigger in the control group than the study group.Hypermyoglobinemia is a common and prominent lab abnormality after CRS + HIPEC, and serum Mb levels could be an early and sensitive indicator for dramatic disturbances in the internal milieu after CRS + HIPEC. Adequate treatment with sodium bicarbonate could accelerate the reduction in serum Mb levels and reduce the risk for major organ damages." @default.
- W2767474140 created "2017-11-17" @default.
- W2767474140 creator A5005939782 @default.
- W2767474140 creator A5008106788 @default.
- W2767474140 creator A5038849229 @default.
- W2767474140 creator A5039519985 @default.
- W2767474140 creator A5058637832 @default.
- W2767474140 creator A5067066167 @default.
- W2767474140 creator A5085972486 @default.
- W2767474140 date "2017-11-01" @default.
- W2767474140 modified "2023-09-23" @default.
- W2767474140 title "Treatment of hypermyoglobinemia after CRS + HIPEC for patients with peritoneal carcinomatosis" @default.
- W2767474140 cites W136765594 @default.
- W2767474140 cites W1552831626 @default.
- W2767474140 cites W1582669297 @default.
- W2767474140 cites W17791541 @default.
- W2767474140 cites W1964545956 @default.
- W2767474140 cites W2004554342 @default.
- W2767474140 cites W2038967212 @default.
- W2767474140 cites W2063098268 @default.
- W2767474140 cites W2097198751 @default.
- W2767474140 cites W2102556842 @default.
- W2767474140 cites W2107037361 @default.
- W2767474140 cites W2229537746 @default.
- W2767474140 cites W2297686622 @default.
- W2767474140 cites W2341937408 @default.
- W2767474140 cites W2346160023 @default.
- W2767474140 cites W2412189923 @default.
- W2767474140 cites W2419559020 @default.
- W2767474140 cites W2473173128 @default.
- W2767474140 cites W2510214769 @default.
- W2767474140 cites W4246496375 @default.
- W2767474140 doi "https://doi.org/10.1097/md.0000000000008573" @default.
- W2767474140 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5690772" @default.
- W2767474140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29137079" @default.
- W2767474140 hasPublicationYear "2017" @default.
- W2767474140 type Work @default.
- W2767474140 sameAs 2767474140 @default.
- W2767474140 citedByCount "4" @default.
- W2767474140 countsByYear W27674741402018 @default.
- W2767474140 countsByYear W27674741402019 @default.
- W2767474140 countsByYear W27674741402021 @default.
- W2767474140 countsByYear W27674741402022 @default.
- W2767474140 crossrefType "journal-article" @default.
- W2767474140 hasAuthorship W2767474140A5005939782 @default.
- W2767474140 hasAuthorship W2767474140A5008106788 @default.
- W2767474140 hasAuthorship W2767474140A5038849229 @default.
- W2767474140 hasAuthorship W2767474140A5039519985 @default.
- W2767474140 hasAuthorship W2767474140A5058637832 @default.
- W2767474140 hasAuthorship W2767474140A5067066167 @default.
- W2767474140 hasAuthorship W2767474140A5085972486 @default.
- W2767474140 hasBestOaLocation W27674741401 @default.
- W2767474140 hasConcept C121608353 @default.
- W2767474140 hasConcept C126322002 @default.
- W2767474140 hasConcept C126894567 @default.
- W2767474140 hasConcept C141071460 @default.
- W2767474140 hasConcept C147789679 @default.
- W2767474140 hasConcept C185592680 @default.
- W2767474140 hasConcept C2776420369 @default.
- W2767474140 hasConcept C2776694085 @default.
- W2767474140 hasConcept C2778176769 @default.
- W2767474140 hasConcept C2779458272 @default.
- W2767474140 hasConcept C2780306776 @default.
- W2767474140 hasConcept C2780427987 @default.
- W2767474140 hasConcept C2781413609 @default.
- W2767474140 hasConcept C2994223192 @default.
- W2767474140 hasConcept C71924100 @default.
- W2767474140 hasConcept C90924648 @default.
- W2767474140 hasConceptScore W2767474140C121608353 @default.
- W2767474140 hasConceptScore W2767474140C126322002 @default.
- W2767474140 hasConceptScore W2767474140C126894567 @default.
- W2767474140 hasConceptScore W2767474140C141071460 @default.
- W2767474140 hasConceptScore W2767474140C147789679 @default.
- W2767474140 hasConceptScore W2767474140C185592680 @default.
- W2767474140 hasConceptScore W2767474140C2776420369 @default.
- W2767474140 hasConceptScore W2767474140C2776694085 @default.
- W2767474140 hasConceptScore W2767474140C2778176769 @default.
- W2767474140 hasConceptScore W2767474140C2779458272 @default.
- W2767474140 hasConceptScore W2767474140C2780306776 @default.
- W2767474140 hasConceptScore W2767474140C2780427987 @default.
- W2767474140 hasConceptScore W2767474140C2781413609 @default.
- W2767474140 hasConceptScore W2767474140C2994223192 @default.
- W2767474140 hasConceptScore W2767474140C71924100 @default.
- W2767474140 hasConceptScore W2767474140C90924648 @default.
- W2767474140 hasIssue "45" @default.
- W2767474140 hasLocation W27674741401 @default.
- W2767474140 hasLocation W27674741402 @default.
- W2767474140 hasLocation W27674741403 @default.
- W2767474140 hasLocation W27674741404 @default.
- W2767474140 hasLocation W27674741405 @default.
- W2767474140 hasOpenAccess W2767474140 @default.
- W2767474140 hasPrimaryLocation W27674741401 @default.
- W2767474140 hasRelatedWork W2067366728 @default.
- W2767474140 hasRelatedWork W2080938381 @default.
- W2767474140 hasRelatedWork W2419064735 @default.
- W2767474140 hasRelatedWork W2517704322 @default.
- W2767474140 hasRelatedWork W2581545833 @default.
- W2767474140 hasRelatedWork W2615904540 @default.