FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767538363> ?p ?o ?g. }

• W2767538363 endingPage "115" @default.
• W2767538363 startingPage "109" @default.
• W2767538363 abstract "Increasing evidence supports the notion that the neurodegenerative process occurring in Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis (ALS) does not only imply the neuronal compartment but also involves a strong interaction with the immunological cells of the Central Nervous System (CNS), primarily microglia. Starting from the observation that the neurodegenerative disorders are frequent in elderly individuals, who have an immunological background that possibly favors this process, it is evident that a dysregulation of innate immune response triggered by misfolded and aggregated proteins, or by endogenous molecules released by injured neurons, directly contributes to disease pathogenesis and progression. There are important differences in the immunological processes occurring in AD, PD, ALS involving microglial function. Furthermore, although the contribution of adaptive immune cells in AD seems to be modest, in PD and especially in ALS models, T cells can influence microglial phenotype, inducing neuroprotection. A better understanding of the immunological mechanisms involved in the different phases of the neurodegenerative processes observed in AD, PD, ALS could effectively contribute to the development of new preventive and therapeutic strategies for such diseases." @default.
• W2767538363 created "2017-11-17" @default.
• W2767538363 creator A5011970616 @default.
• W2767538363 creator A5029025188 @default.
• W2767538363 date "2017-12-01" @default.
• W2767538363 modified "2023-09-23" @default.
• W2767538363 title "Neurodegenerative diseases: The immunological perspective" @default.
• W2767538363 cites W1482873758 @default.
• W2767538363 cites W1502339857 @default.
• W2767538363 cites W1508177354 @default.
• W2767538363 cites W1546232808 @default.
• W2767538363 cites W1552917612 @default.
• W2767538363 cites W1588685142 @default.
• W2767538363 cites W1623920471 @default.
• W2767538363 cites W1763258797 @default.
• W2767538363 cites W1820035495 @default.
• W2767538363 cites W1841850981 @default.
• W2767538363 cites W1965624208 @default.
• W2767538363 cites W1965942744 @default.
• W2767538363 cites W197102779 @default.
• W2767538363 cites W1974834425 @default.
• W2767538363 cites W1976266513 @default.
• W2767538363 cites W1977585036 @default.
• W2767538363 cites W1978793403 @default.
• W2767538363 cites W1980608200 @default.
• W2767538363 cites W1982739794 @default.
• W2767538363 cites W1987138690 @default.
• W2767538363 cites W1989339029 @default.
• W2767538363 cites W1995357368 @default.
• W2767538363 cites W1999516517 @default.
• W2767538363 cites W2003757791 @default.
• W2767538363 cites W2008481778 @default.
• W2767538363 cites W2009839264 @default.
• W2767538363 cites W2012662246 @default.
• W2767538363 cites W2029807159 @default.
• W2767538363 cites W2033158384 @default.
• W2767538363 cites W2033617297 @default.
• W2767538363 cites W2037099926 @default.
• W2767538363 cites W2038594716 @default.
• W2767538363 cites W2039010656 @default.
• W2767538363 cites W2043683714 @default.
• W2767538363 cites W2045772297 @default.
• W2767538363 cites W2049733399 @default.
• W2767538363 cites W2051776695 @default.
• W2767538363 cites W2054876142 @default.
• W2767538363 cites W2055348159 @default.
• W2767538363 cites W2058742494 @default.
• W2767538363 cites W2059248106 @default.
• W2767538363 cites W2064046464 @default.
• W2767538363 cites W2069842601 @default.
• W2767538363 cites W2071079513 @default.
• W2767538363 cites W2071753918 @default.
• W2767538363 cites W2073449985 @default.
• W2767538363 cites W2075691498 @default.
• W2767538363 cites W2077331144 @default.
• W2767538363 cites W2079873627 @default.
• W2767538363 cites W2083556882 @default.
• W2767538363 cites W2087123644 @default.
• W2767538363 cites W2090930997 @default.
• W2767538363 cites W2094272888 @default.
• W2767538363 cites W2096401612 @default.
• W2767538363 cites W2096500024 @default.
• W2767538363 cites W2098432330 @default.
• W2767538363 cites W2099005297 @default.
• W2767538363 cites W2101243397 @default.
• W2767538363 cites W2101363646 @default.
• W2767538363 cites W2111464898 @default.
• W2767538363 cites W2112815582 @default.
• W2767538363 cites W2114926230 @default.
• W2767538363 cites W2117266418 @default.
• W2767538363 cites W2124667416 @default.
• W2767538363 cites W2127716652 @default.
• W2767538363 cites W2128631317 @default.
• W2767538363 cites W2133712961 @default.
• W2767538363 cites W2135768865 @default.
• W2767538363 cites W2136302772 @default.
• W2767538363 cites W2138192231 @default.
• W2767538363 cites W2138274802 @default.
• W2767538363 cites W2139463652 @default.
• W2767538363 cites W2141976392 @default.
• W2767538363 cites W2144507462 @default.
• W2767538363 cites W2149399096 @default.
• W2767538363 cites W2150128864 @default.
• W2767538363 cites W2151844149 @default.
• W2767538363 cites W2163751922 @default.
• W2767538363 cites W2164191009 @default.
• W2767538363 cites W2165863447 @default.
• W2767538363 cites W2172694294 @default.
• W2767538363 cites W2261364877 @default.
• W2767538363 cites W2272581670 @default.
• W2767538363 cites W2520091477 @default.
• W2767538363 cites W2538708794 @default.
• W2767538363 cites W2560668196 @default.
• W2767538363 cites W2604638361 @default.
• W2767538363 cites W2740246561 @default.
• W2767538363 cites W2743037209 @default.
• W2767538363 cites W2913609543 @default.
• W2767538363 cites W4211151576 @default.

• next