FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767611854> ?p ?o ?g. }

• W2767611854 abstract "Telomerase is an ancient ribonucleoprotein (RNP) that protects the ends of linear chromosomes from the loss of critical coding sequences through repetitive addition of short DNA sequences. These repeats comprise the telomere, which together with many accessory proteins, protect chromosomal ends from degradation and unwanted DNA repair. Telomerase is a unique reverse transcriptase (RT) that carries its own RNA to use as a template for repeat addition. Over decades of research, it has become clear that there are many diverse, crucial functions played by telomerase RNA beyond simply acting as a template. In this review, we highlight recent findings in three model systems: ciliates, yeast and vertebrates, that have shifted the way the field views the structural and mechanistic role(s) of RNA within the functional telomerase RNP complex. Viewed in this light, we hope to demonstrate that while telomerase RNA is just one example of the myriad functional RNA in the cell, insights into its structure and mechanism have wide‐ranging impacts. WIREs RNA 2018, 9:e1456. doi: 10.1002/wrna.1456 This article is categorized under: RNA Structure and Dynamics > Influence of RNA Structure in Biological Systems RNA Structure and Dynamics > RNA Structure, Dynamics and Chemistry RNA Evolution and Genomics > RNA and Ribonucleoprotein Evolution" @default.
• W2767611854 created "2017-11-17" @default.
• W2767611854 creator A5022948046 @default.
• W2767611854 creator A5025202819 @default.
• W2767611854 creator A5039931180 @default.
• W2767611854 date "2017-11-09" @default.
• W2767611854 modified "2023-10-17" @default.
• W2767611854 title "New perspectives on telomerase RNA structure and function" @default.
• W2767611854 cites W14498347 @default.
• W2767611854 cites W1497143641 @default.
• W2767611854 cites W1577250214 @default.
• W2767611854 cites W1825955700 @default.
• W2767611854 cites W1852687820 @default.
• W2767611854 cites W1915004688 @default.
• W2767611854 cites W1921803558 @default.
• W2767611854 cites W1965130367 @default.
• W2767611854 cites W1966370842 @default.
• W2767611854 cites W1967405092 @default.
• W2767611854 cites W1970770718 @default.
• W2767611854 cites W1978611207 @default.
• W2767611854 cites W1984219012 @default.
• W2767611854 cites W1995875896 @default.
• W2767611854 cites W2000571874 @default.
• W2767611854 cites W2000971601 @default.
• W2767611854 cites W2004459276 @default.
• W2767611854 cites W2004561527 @default.
• W2767611854 cites W2004748235 @default.
• W2767611854 cites W2007550449 @default.
• W2767611854 cites W2009357812 @default.
• W2767611854 cites W2010070807 @default.
• W2767611854 cites W2010588560 @default.
• W2767611854 cites W2011251205 @default.
• W2767611854 cites W2012337056 @default.
• W2767611854 cites W2014482493 @default.
• W2767611854 cites W2020066813 @default.
• W2767611854 cites W2020923999 @default.
• W2767611854 cites W2021489383 @default.
• W2767611854 cites W2024550280 @default.
• W2767611854 cites W2026034698 @default.
• W2767611854 cites W2029692556 @default.
• W2767611854 cites W2035388920 @default.
• W2767611854 cites W2043764151 @default.
• W2767611854 cites W2045539866 @default.
• W2767611854 cites W2050168806 @default.
• W2767611854 cites W2052351457 @default.
• W2767611854 cites W2053620236 @default.
• W2767611854 cites W2053875211 @default.
• W2767611854 cites W2059422889 @default.
• W2767611854 cites W2059665929 @default.
• W2767611854 cites W2059683014 @default.
• W2767611854 cites W2070857389 @default.
• W2767611854 cites W2075387685 @default.
• W2767611854 cites W2083968461 @default.
• W2767611854 cites W2090526557 @default.
• W2767611854 cites W2097110171 @default.
• W2767611854 cites W2099610235 @default.
• W2767611854 cites W2100057014 @default.
• W2767611854 cites W2101289497 @default.
• W2767611854 cites W2102490688 @default.
• W2767611854 cites W2106850855 @default.
• W2767611854 cites W2108503708 @default.
• W2767611854 cites W2110429725 @default.
• W2767611854 cites W2122740168 @default.
• W2767611854 cites W2126535236 @default.
• W2767611854 cites W2128133969 @default.
• W2767611854 cites W2134759743 @default.
• W2767611854 cites W2136440665 @default.
• W2767611854 cites W2137155383 @default.
• W2767611854 cites W2140944222 @default.
• W2767611854 cites W2142298035 @default.
• W2767611854 cites W2142844453 @default.
• W2767611854 cites W2145492630 @default.
• W2767611854 cites W2145715750 @default.
• W2767611854 cites W2148955775 @default.
• W2767611854 cites W2151639455 @default.
• W2767611854 cites W2155944730 @default.
• W2767611854 cites W2157330538 @default.
• W2767611854 cites W2157638309 @default.
• W2767611854 cites W2159539672 @default.
• W2767611854 cites W2160185049 @default.
• W2767611854 cites W2160664302 @default.
• W2767611854 cites W2163579602 @default.
• W2767611854 cites W2164412172 @default.
• W2767611854 cites W2164449007 @default.
• W2767611854 cites W2168278822 @default.
• W2767611854 cites W2169812949 @default.
• W2767611854 cites W2170176918 @default.
• W2767611854 cites W2287595419 @default.
• W2767611854 cites W2320136840 @default.
• W2767611854 cites W2416398842 @default.
• W2767611854 cites W2474358581 @default.
• W2767611854 cites W2515189672 @default.
• W2767611854 cites W2554089298 @default.
• W2767611854 cites W2554540578 @default.
• W2767611854 cites W2555177662 @default.
• W2767611854 cites W2559011405 @default.
• W2767611854 cites W2608529791 @default.
• W2767611854 doi "https://doi.org/10.1002/wrna.1456" @default.
• W2767611854 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5815921" @default.
• W2767611854 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29124890" @default.

• next