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- W2767619904 abstract "The evolution of microorganisms resistant to many medicines has become a major challenge for the scientific community around the world. Motivated by the gravity of such a situation, the World Health Organization released a report in 2014 with the aim of providing updated information on this critical scenario. Among the most worrying microorganisms, species from the genus Candida have exhibited a high rate of resistance to antifungal drugs. Therefore, the objective of this review is to show that the use of natural products (extracts or isolated biomolecules), along with conventional antifungal therapy, can be a very promising strategy to overcome microbial multiresistance. Some promising alternatives are essential oils of Melaleuca alternifolia (mainly composed of terpinen-4-ol, a type of monoterpene), lactoferrin (a peptide isolated from milk) and chitosan (a copolymer from chitin). Such products have great potential to increase antifungal therapy efficacy, mitigate side effects and provide a wide range of action in antifungal therapy." @default.
- W2767619904 created "2017-11-17" @default.
- W2767619904 creator A5017528156 @default.
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- W2767619904 creator A5080520870 @default.
- W2767619904 creator A5084832341 @default.
- W2767619904 date "2018-04-01" @default.
- W2767619904 modified "2023-10-10" @default.
- W2767619904 title "Lactoferrin, chitosan and Melaleuca alternifolia —natural products that show promise in candidiasis treatment" @default.
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- W2767619904 doi "https://doi.org/10.1016/j.bjm.2017.05.008" @default.
- W2767619904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5913821" @default.
- W2767619904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29132828" @default.
- W2767619904 hasPublicationYear "2018" @default.
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