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- W2767636641 abstract "La enfermedad de Parkinson (EP) es un tipo de parkinsonismo idiopático primario, con degeneración de neuronas dopaminérgicas nigroestriatales. En Argentina no existen datos oficiales. Se estima 70.000 personas afectadas. Existen otros parkinsonismos: secundarios, atípicos y hereditarios con síntomas similares. Su diagnóstico diferencial es clave. Las modalidades imagenológicas tradicionales (TC/RMN) aportan escasa información en EP. Otros métodos dan información pero con costo elevado. La eco-TM sería un recurso valioso para un diagnóstico precoz. Reconocer hallazgos con eco-TM en EP y parkinsonismos. Correlacionar con TAC y RMN. Determinar sensibilidad, especificidad y VPP del estudio en la población estudiada. Estudio descriptivo, observacional, corte transversal, realizado en el Instituto de Bioelectrónica (FMUNT), Centro Neurológico Tucumán CENTUC, y Hospital Centro de Salud Zenón Santillán, entre noviembre de 2015 y octubre de 2016. Se seleccionaron 22 pacientes, derivados de Servicio Neurológico Privado CENTUC, de San Miguel de Tucumán, al servicio de Ecografía del Hospital Centro de Salud Zenón Santillán. Se dividieron en 2 grupos: con EP y con parkinsonismo, realizándoseles una ETM. Un 59,09%(n = 13) fueron varones. El 68,22% (n = 15) pacientes con EP. Un 18,18% (n = 4) pacientes con parkinsonismo. El 66,67% (n = 10) de los pacientes con EP, tuvieron imágenes hiperecogénicas mesencefálicas en eco-TM. Todos tenían TAC/RMN normales. Los parkinsonismos no presentaron imágenes hiperecogénicas en eco-TM. Sensibilidad del 66,67%, especificidad del 100% y VPP del 100%. Consideramos la eco-TM un valioso método de diagnóstico, identificando lesiones específicas de EP a un bajo costo, no invasivo y con incidencia en pronóstico y tratamiento. Parkinson's disease (PD) is a type of primary idiopathic parkinsonism, with progressive degeneration of dopaminergic nigrostriatal neurons. In Argentina there are no official data on this condition. It is estimated that 70,000 people suffer from the disease. There are other parkinsonisms –i.e., secondary, atypical and hereditary– with similar symptoms. CT scan and MRI provide little information on PD. Other methods provide more information but are more costly. The TM Ultrasound (TMUlt) would be a valuable resource for early diagnosis. To recognize TMUlt findings in PD and parkinsonisms. To correlate them with TC and MRI findings. To determine the sensitivity, specificity and PPV on the population studied. A descriptive, observational, cross-sectional study carried out at the Institute of Bioelectronics (FMUNT), CENTUC Neurological Center and Zenón Santillán Hospital (Tucumán, Argentina), between November 2015 and October 2016. We selected 22 patients derived from CENTUC to the Hospital's Ultrasound Service. They were divided into 2 groups: patients with PD and patients parkinsonism. All of them were administered a TMUlt. 59.09% (n = 13) were men; 68.22% (n = 15) patients had a diagnosis of PD; 18.18% (n = 4) patients had a diagnosis of parkinsonism. 66.67% (n = 10) of patients with PD had hiperechogenic images in the midbrain in the TMUlt. All of them had normal CT/ MRI. Parkinsonisms did not present pathological images at the TMUlt. Sensitivity was 66.67% and specificity was 100% and 100% at the PPV. We consider that TMUlt is a valuable diagnostic method to identify PD-specific injuries with a low-cost, non-invasive method and a high incidence in the prognosis and treatment of the disease." @default.
- W2767636641 created "2017-11-17" @default.
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- W2767636641 date "2017-10-01" @default.
- W2767636641 modified "2023-09-26" @default.
- W2767636641 title "Ecografía transcraneal mesencefálica en el estudio de enfermedad de Parkinson y su diagnóstico diferencial con parkinsonismos en un hospital público de Tucumán" @default.
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- W2767636641 doi "https://doi.org/10.1016/j.neuarg.2017.09.001" @default.
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