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- W2767672214 endingPage "85" @default.
- W2767672214 startingPage "53" @default.
- W2767672214 abstract "This chapter discusses Chagas' disease. Trypanosoma cruzi, which is the protozoan parasite causing Chagas' disease, represents the most significant health problem in the American continent in terms of human health, socioeconomic impact, and geographic distribution. This parasite also affects a large number of mammalian species. The life cycle involves transmission by blood-sucking reduviid insects that carry infective forms of T. cruzi in their fecal fluids and deposit them on the skin at the time of procuring a blood meal. After entering the body through skin lesions or mucosal surfaces, the parasite may penetrate a variety of host cells. In the host cells' cytoplasm, it transforms into the amastigote form capable of intracellular replication. Eventually, further intracellular transformation gives rise to a trypomastigote form commonly found in tissue fluids and in the blood, through which it can be disseminated to other cells and tissues or from where it could be ingested by an insect vector. In endemic areas, individuals are usually infected during childhood. In cases where the disease becomes patent, the acute disease can develop in a few weeks and leads to high fever." @default.
- W2767672214 created "2017-11-17" @default.
- W2767672214 creator A5013151184 @default.
- W2767672214 creator A5014946608 @default.
- W2767672214 date "1994-01-01" @default.
- W2767672214 modified "2023-09-23" @default.
- W2767672214 title "Chagas' Disease (American Trypanosomiasis)" @default.
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