Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767729246> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2767729246 abstract "Objective: The objectives of the present research was to develop a simple, precise, economical, accurate, reproducible and sensitive method for the quantitative estimation of lafutidine in bulk and its pharmaceutical dosage forms by Ultra Violet (UV) absorption spectrophotometry.Methods: The method uses 0.1 N HCl, pH 1.20 as a solvent of choice for the quantitative estimation of lafutidine in bulk and its tablets dosage form by UV absorption spectrophotometry at a wavelength of 290 nm. The method was validated for parameters like linearity, range, precision, Limit of Detection (LOD), Limit of Quantification (LOQ), accuracy, recovery and stability of the analyte.Results: Lafutidine exhibited absorbance maxima at 290 nm in 0.1 N HCl, pH 1.20 solvent. The developed method was validated as per the ICH validation guidelines. Beer’s law was obeyed in range of 0-30 µg/ml with r2= 0.9997. The LOD and LOQ values of lafutidine were found to be 0.545 µg/ml and 1.654 µg/ml respectively. The mean % recovery for the developed method was found to be in the range of 99.25 to 99.45 % respectively for the marketed dosage forms. The developed method was also found to be robust.Conclusion: The developed method was found suitable for the routine quantitative analysis of lafutidinein bulk and pharmaceutical dosage form. It was also concluded that developed UV spectrophotometry method was accurate, precise, linear, reproducible, robust and sensitive." @default.
- W2767729246 created "2017-11-17" @default.
- W2767729246 creator A5030492797 @default.
- W2767729246 creator A5038555835 @default.
- W2767729246 creator A5044204819 @default.
- W2767729246 creator A5073272594 @default.
- W2767729246 date "2017-11-08" @default.
- W2767729246 modified "2023-09-25" @default.
- W2767729246 title "DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD FOR QUANTITATIVE ESTIMATION OF LAFUTIDINE IN BULK AND PHARMACEUTICAL DOSAGE FORM" @default.
- W2767729246 doi "https://doi.org/10.22159/ijap.2017v9i6.21943" @default.
- W2767729246 hasPublicationYear "2017" @default.
- W2767729246 type Work @default.
- W2767729246 sameAs 2767729246 @default.
- W2767729246 citedByCount "2" @default.
- W2767729246 countsByYear W27677292462018 @default.
- W2767729246 countsByYear W27677292462023 @default.
- W2767729246 crossrefType "journal-article" @default.
- W2767729246 hasAuthorship W2767729246A5030492797 @default.
- W2767729246 hasAuthorship W2767729246A5038555835 @default.
- W2767729246 hasAuthorship W2767729246A5044204819 @default.
- W2767729246 hasAuthorship W2767729246A5073272594 @default.
- W2767729246 hasBestOaLocation W27677292461 @default.
- W2767729246 hasConcept C10390740 @default.
- W2767729246 hasConcept C106186310 @default.
- W2767729246 hasConcept C113196181 @default.
- W2767729246 hasConcept C119128265 @default.
- W2767729246 hasConcept C178790620 @default.
- W2767729246 hasConcept C185592680 @default.
- W2767729246 hasConcept C2780343419 @default.
- W2767729246 hasConcept C2780471494 @default.
- W2767729246 hasConcept C43617362 @default.
- W2767729246 hasConcept C77281830 @default.
- W2767729246 hasConcept C95986675 @default.
- W2767729246 hasConcept C98015330 @default.
- W2767729246 hasConceptScore W2767729246C10390740 @default.
- W2767729246 hasConceptScore W2767729246C106186310 @default.
- W2767729246 hasConceptScore W2767729246C113196181 @default.
- W2767729246 hasConceptScore W2767729246C119128265 @default.
- W2767729246 hasConceptScore W2767729246C178790620 @default.
- W2767729246 hasConceptScore W2767729246C185592680 @default.
- W2767729246 hasConceptScore W2767729246C2780343419 @default.
- W2767729246 hasConceptScore W2767729246C2780471494 @default.
- W2767729246 hasConceptScore W2767729246C43617362 @default.
- W2767729246 hasConceptScore W2767729246C77281830 @default.
- W2767729246 hasConceptScore W2767729246C95986675 @default.
- W2767729246 hasConceptScore W2767729246C98015330 @default.
- W2767729246 hasLocation W27677292461 @default.
- W2767729246 hasOpenAccess W2767729246 @default.
- W2767729246 hasPrimaryLocation W27677292461 @default.
- W2767729246 hasRelatedWork W1486569674 @default.
- W2767729246 hasRelatedWork W2014499163 @default.
- W2767729246 hasRelatedWork W2117685620 @default.
- W2767729246 hasRelatedWork W2234770698 @default.
- W2767729246 hasRelatedWork W2619089035 @default.
- W2767729246 hasRelatedWork W2735635015 @default.
- W2767729246 hasRelatedWork W2740398991 @default.
- W2767729246 hasRelatedWork W2766447929 @default.
- W2767729246 hasRelatedWork W2890157106 @default.
- W2767729246 hasRelatedWork W2919289016 @default.
- W2767729246 hasRelatedWork W2974105892 @default.
- W2767729246 hasRelatedWork W2995379116 @default.
- W2767729246 hasRelatedWork W2184754615 @default.
- W2767729246 hasRelatedWork W2184875376 @default.
- W2767729246 hasRelatedWork W2185658019 @default.
- W2767729246 hasRelatedWork W2185766307 @default.
- W2767729246 hasRelatedWork W2189241842 @default.
- W2767729246 hasRelatedWork W2189284496 @default.
- W2767729246 hasRelatedWork W2340761294 @default.
- W2767729246 hasRelatedWork W2736875110 @default.
- W2767729246 isParatext "false" @default.
- W2767729246 isRetracted "false" @default.
- W2767729246 magId "2767729246" @default.
- W2767729246 workType "article" @default.