FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767815794> ?p ?o ?g. }

• W2767815794 endingPage "2737" @default.
• W2767815794 startingPage "2732" @default.
• W2767815794 abstract "Objective: Intrauterine adhesion (IUA) is a major health problem that causes infertility, menstrual irregularities, and recurrent pregnancy losses in women. Unfortunately, treatments for IUA are limited, and there are currently no effective strategies for preventing IUA recurrence. In this review, we introduced the role of Hippo signaling in the normal endometrium and IUA and described the mechanisms by which the Hippo pathway integrates with the Wnt and transforming growth factor-β (TGF-β) signaling pathways to form an intricate network governing the development of fibrosis. Data Sources: Original research articles in English that were published until July 2017 were collected from the PubMed database. Study Selection: Literature search was conducted using the search terms “endometrial fibrosis OR fibrosis AND or OR intrauterine adhesion OR Asherman syndrome OR IUA,” “Hippo AND or OR Hippo/TAZ,” “TGF-β,” and “Wnt.” Related original research articles were included in the comprehensive analysis. Results: Endometrial fibrosis is recognized as a key pathological event in the development of IUA, which is characterized by epithelial/fibroblast–myofibroblast transition. Myofibroblasts play crucial roles in the pathogenesis of fibrous scarring, and myofibroblast differentiation can be triggered by multiple signaling pathways. Hippo signaling is a critical regulator of the epithelial/fibroblast–myofibroblast transition and α-smooth muscle actin, which exhibits a specific spatiotemporal expression in the endometrium. Conclusions: Hippo signaling plays a critical role in fibrous diseases and participates in cross talks with Wnt and TGF-β signaling. Our findings not only contributed to knowledge on the pathogenesis of endometrial fibrosis, but can also serve as a useful resource for developing specific molecular inhibitors for IUA treatment and prevention." @default.
• W2767815794 created "2017-11-17" @default.
• W2767815794 creator A5006301859 @default.
• W2767815794 creator A5008786007 @default.
• W2767815794 creator A5044797020 @default.
• W2767815794 creator A5063310759 @default.
• W2767815794 date "2017-11-20" @default.
• W2767815794 modified "2023-10-12" @default.
• W2767815794 title "Advanced Role of Hippo Signaling in Endometrial Fibrosis" @default.
• W2767815794 cites W1547422910 @default.
• W2767815794 cites W1683571557 @default.
• W2767815794 cites W1914659192 @default.
• W2767815794 cites W1925728463 @default.
• W2767815794 cites W1966554114 @default.
• W2767815794 cites W1974663321 @default.
• W2767815794 cites W1977416672 @default.
• W2767815794 cites W1978746441 @default.
• W2767815794 cites W1993600822 @default.
• W2767815794 cites W1996690536 @default.
• W2767815794 cites W2002935073 @default.
• W2767815794 cites W2007916618 @default.
• W2767815794 cites W2008439293 @default.
• W2767815794 cites W2011346718 @default.
• W2767815794 cites W2016390482 @default.
• W2767815794 cites W2016672123 @default.
• W2767815794 cites W2019834759 @default.
• W2767815794 cites W2021590728 @default.
• W2767815794 cites W2024440558 @default.
• W2767815794 cites W2025620210 @default.
• W2767815794 cites W2027150010 @default.
• W2767815794 cites W2032622848 @default.
• W2767815794 cites W2033360354 @default.
• W2767815794 cites W2034469841 @default.
• W2767815794 cites W2042635844 @default.
• W2767815794 cites W2048717495 @default.
• W2767815794 cites W2059114286 @default.
• W2767815794 cites W2067541494 @default.
• W2767815794 cites W2071765960 @default.
• W2767815794 cites W2071883174 @default.
• W2767815794 cites W2073568903 @default.
• W2767815794 cites W2080519990 @default.
• W2767815794 cites W2085197940 @default.
• W2767815794 cites W2100141065 @default.
• W2767815794 cites W2104906501 @default.
• W2767815794 cites W2105973884 @default.
• W2767815794 cites W2107888949 @default.
• W2767815794 cites W2122585556 @default.
• W2767815794 cites W2122808924 @default.
• W2767815794 cites W2123460271 @default.
• W2767815794 cites W2130146890 @default.
• W2767815794 cites W2135726634 @default.
• W2767815794 cites W2141595533 @default.
• W2767815794 cites W2143227567 @default.
• W2767815794 cites W2143735061 @default.
• W2767815794 cites W2148056172 @default.
• W2767815794 cites W2151260549 @default.
• W2767815794 cites W2153777951 @default.
• W2767815794 cites W2163615020 @default.
• W2767815794 cites W2168072233 @default.
• W2767815794 cites W2171484508 @default.
• W2767815794 cites W2171875732 @default.
• W2767815794 cites W2209916898 @default.
• W2767815794 cites W2221679805 @default.
• W2767815794 cites W2301845119 @default.
• W2767815794 cites W2345326892 @default.
• W2767815794 cites W2481761423 @default.
• W2767815794 cites W2507196425 @default.
• W2767815794 cites W2524151805 @default.
• W2767815794 cites W2552877395 @default.
• W2767815794 cites W2556156445 @default.
• W2767815794 cites W2596063513 @default.
• W2767815794 cites W2602581116 @default.
• W2767815794 cites W2619802933 @default.
• W2767815794 cites W2737033892 @default.
• W2767815794 cites W311938958 @default.
• W2767815794 doi "https://doi.org/10.4103/0366-6999.218013" @default.
• W2767815794 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5695061" @default.
• W2767815794 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29133764" @default.
• W2767815794 hasPublicationYear "2017" @default.
• W2767815794 type Work @default.
• W2767815794 sameAs 2767815794 @default.
• W2767815794 citedByCount "55" @default.
• W2767815794 countsByYear W27678157942018 @default.
• W2767815794 countsByYear W27678157942019 @default.
• W2767815794 countsByYear W27678157942020 @default.
• W2767815794 countsByYear W27678157942021 @default.
• W2767815794 countsByYear W27678157942022 @default.
• W2767815794 countsByYear W27678157942023 @default.
• W2767815794 crossrefType "journal-article" @default.
• W2767815794 hasAuthorship W2767815794A5006301859 @default.
• W2767815794 hasAuthorship W2767815794A5008786007 @default.
• W2767815794 hasAuthorship W2767815794A5044797020 @default.
• W2767815794 hasAuthorship W2767815794A5063310759 @default.
• W2767815794 hasBestOaLocation W27678157941 @default.
• W2767815794 hasConcept C118131993 @default.
• W2767815794 hasConcept C121608353 @default.
• W2767815794 hasConcept C126322002 @default.
• W2767815794 hasConcept C137620995 @default.

• next