FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767875892> ?p ?o ?g. }

• W2767875892 endingPage "267" @default.
• W2767875892 startingPage "262" @default.
• W2767875892 abstract "This study was designed to examine the contribution of oxidative stress in gastrointestinal disorders after an intraperitoneal administration of 5 fluorouracil (5-FU; 100 mg/kg of body weight (b.w.)) and capecitabine oral administration (500 mg/kg b.w.). The animals were divided into three groups: Group A (NaCl,10 ml/kg of b.w.) considered as control group, group B was intoxicated by 5-FU and group C was the group of animals treated with capecitabine (CAP). To evaluate the secretory and enteropooling effects, we used magnesium sulfate (MgSO4), 1 ml/100 g of b.w. as a hypersecretion agent . The mucosal gastro-intestinal specimens were scraped and examined for biological markers of oxidative stress and intracellular mediators. These anticancer drugs caused many intestinal damages manifested by an elevation of fluid accumulation and imbalance in electrolytes secretion. The intestinal tissues from treated rats not only showed a significant increase in malondialdehyde (MDA), protein carbonylation and hydrogen peroxide (H2O2) production. but also showed a significant depletion of enzymatic and non-enzymatic antioxidant, such as, glutathione peroxidase (GPx), superoxide dismutase (SOD), catalase (CAT) and sulfhydryl groups (-SH). These effects were related with histopathological damage and a perturbation of intracellular mediators. As expected, these disturbances were observed in the group of rats poisoned by the MgSO4. Data suggest the contribution of oxidative stress in chemotherapy-induced many disorders in intestinal tract." @default.
• W2767875892 created "2017-11-17" @default.
• W2767875892 creator A5008251296 @default.
• W2767875892 creator A5009557857 @default.
• W2767875892 creator A5017581460 @default.
• W2767875892 creator A5023613309 @default.
• W2767875892 creator A5036166134 @default.
• W2767875892 creator A5063458324 @default.
• W2767875892 date "2017-11-24" @default.
• W2767875892 modified "2023-09-23" @default.
• W2767875892 title "Contribution of oxidative stress in acute intestinal mucositis induced by 5 fluorouracil (5-FU) and its pro-drug capecitabine in rats" @default.
• W2767875892 cites W1490663175 @default.
• W2767875892 cites W1538399032 @default.
• W2767875892 cites W1546592314 @default.
• W2767875892 cites W1567614586 @default.
• W2767875892 cites W1850804383 @default.
• W2767875892 cites W1919038953 @default.
• W2767875892 cites W1938704134 @default.
• W2767875892 cites W1966914913 @default.
• W2767875892 cites W1966935284 @default.
• W2767875892 cites W1988625439 @default.
• W2767875892 cites W2005351330 @default.
• W2767875892 cites W2006330201 @default.
• W2767875892 cites W2006370393 @default.
• W2767875892 cites W2009087143 @default.
• W2767875892 cites W2012865201 @default.
• W2767875892 cites W2047299753 @default.
• W2767875892 cites W2051559169 @default.
• W2767875892 cites W2052278543 @default.
• W2767875892 cites W2052647898 @default.
• W2767875892 cites W2061229425 @default.
• W2767875892 cites W2088476216 @default.
• W2767875892 cites W2091190231 @default.
• W2767875892 cites W2110330635 @default.
• W2767875892 cites W2125060052 @default.
• W2767875892 cites W2132001873 @default.
• W2767875892 cites W2141393521 @default.
• W2767875892 cites W4205407119 @default.
• W2767875892 doi "https://doi.org/10.1080/15376516.2017.1402976" @default.
• W2767875892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29117755" @default.
• W2767875892 hasPublicationYear "2017" @default.
• W2767875892 type Work @default.
• W2767875892 sameAs 2767875892 @default.
• W2767875892 citedByCount "28" @default.
• W2767875892 countsByYear W27678758922018 @default.
• W2767875892 countsByYear W27678758922019 @default.
• W2767875892 countsByYear W27678758922020 @default.
• W2767875892 countsByYear W27678758922021 @default.
• W2767875892 countsByYear W27678758922022 @default.
• W2767875892 countsByYear W27678758922023 @default.
• W2767875892 crossrefType "journal-article" @default.
• W2767875892 hasAuthorship W2767875892A5008251296 @default.
• W2767875892 hasAuthorship W2767875892A5009557857 @default.
• W2767875892 hasAuthorship W2767875892A5017581460 @default.
• W2767875892 hasAuthorship W2767875892A5023613309 @default.
• W2767875892 hasAuthorship W2767875892A5036166134 @default.
• W2767875892 hasAuthorship W2767875892A5063458324 @default.
• W2767875892 hasConcept C126322002 @default.
• W2767875892 hasConcept C181199279 @default.
• W2767875892 hasConcept C185592680 @default.
• W2767875892 hasConcept C2775838275 @default.
• W2767875892 hasConcept C2776151105 @default.
• W2767875892 hasConcept C2778004101 @default.
• W2767875892 hasConcept C2778401633 @default.
• W2767875892 hasConcept C2778760513 @default.
• W2767875892 hasConcept C2778979269 @default.
• W2767875892 hasConcept C538909803 @default.
• W2767875892 hasConcept C55493867 @default.
• W2767875892 hasConcept C71924100 @default.
• W2767875892 hasConcept C98274493 @default.
• W2767875892 hasConceptScore W2767875892C126322002 @default.
• W2767875892 hasConceptScore W2767875892C181199279 @default.
• W2767875892 hasConceptScore W2767875892C185592680 @default.
• W2767875892 hasConceptScore W2767875892C2775838275 @default.
• W2767875892 hasConceptScore W2767875892C2776151105 @default.
• W2767875892 hasConceptScore W2767875892C2778004101 @default.
• W2767875892 hasConceptScore W2767875892C2778401633 @default.
• W2767875892 hasConceptScore W2767875892C2778760513 @default.
• W2767875892 hasConceptScore W2767875892C2778979269 @default.
• W2767875892 hasConceptScore W2767875892C538909803 @default.
• W2767875892 hasConceptScore W2767875892C55493867 @default.
• W2767875892 hasConceptScore W2767875892C71924100 @default.
• W2767875892 hasConceptScore W2767875892C98274493 @default.
• W2767875892 hasIssue "4" @default.
• W2767875892 hasLocation W27678758921 @default.
• W2767875892 hasLocation W27678758922 @default.
• W2767875892 hasOpenAccess W2767875892 @default.
• W2767875892 hasPrimaryLocation W27678758921 @default.
• W2767875892 hasRelatedWork W1967047574 @default.
• W2767875892 hasRelatedWork W1969555927 @default.
• W2767875892 hasRelatedWork W1993548188 @default.
• W2767875892 hasRelatedWork W1999460200 @default.
• W2767875892 hasRelatedWork W2157639809 @default.
• W2767875892 hasRelatedWork W2186775341 @default.
• W2767875892 hasRelatedWork W2213996271 @default.
• W2767875892 hasRelatedWork W2808579078 @default.
• W2767875892 hasRelatedWork W3200659209 @default.
• W2767875892 hasRelatedWork W3214998341 @default.

• next