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• W2767892905 abstract "The long-term impact of treatment strategies proposed by the IDSA guidelines for patients presenting with methicillin-susceptible S. aureus (MSSA) prosthetic joint infection (PJI) is not well-known. Retrospective (2000–2010) cohort study including patients presenting with MSSA hip or knee PJI. A univariate Cox analysis was performed to determine if the non-compliance with IDSA surgical guidelines was a risk factor for treatment failure. Eighty-nine patients with a mean follow-up of 2.8 years were included. Non-compliance with IDSA surgical guidelines was associated with treatment failure (hazard ratio 2.157; 95% CI [1.022–4.7]). The American Society of Anesthesiologists score, inadequate antimicrobial therapy, and a rifampicin-based regimen did not significantly influence patient outcome. Based on the IDSA guidelines, if a patient presenting with MSSA PJI is not eligible for implant retention, complete implant removal is needed to limit treatment failure. L’impact des stratégies proposées par les recommandations de l’IDSA pour les patients présentant une infection de prothèse articulaire (IPA) à S. aureus sensible à la méthicilline (MSSA) n’est pas connu. Étude de cohorte rétrospective (2000–2010) incluant des patients avec une IPA à MSSA. Une analyse univariée de Cox a été utilisée pour déterminer si le non-respect de la stratégie chirurgicale proposée par l’IDSA était associé à un échec. Chez 89 patients avec un suivi médian de 2,8 ans, le non-respect de la stratégie chirurgicale proposée par l’IDSA était associé à un échec (HR 2,157 ; IC 95 % [1,022–4,7]), alors que le score ASA, une antibiothérapie inadéquate et une antibiothérapie contenant de la rifampicine n’influençaient pas le pronostic. Pour les patients présentant une IPA à MSSA ne remplissant pas les critères pour un traitement conservateur, l’ablation totale des implants est requise." @default.
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• W2767892905 date "2018-05-01" @default.
• W2767892905 modified "2023-10-14" @default.
• W2767892905 title "Non-compliance with IDSA guidelines for patients presenting with methicillin-susceptible Staphylococcus aureus prosthetic joint infection is a risk factor for treatment failure" @default.
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• W2767892905 doi "https://doi.org/10.1016/j.medmal.2017.09.016" @default.
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