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- W2767920497 abstract "Primary amidations of carboxylic acids 1 or 3 with NH4Cl in the presence of ClCO2Et and Et3N were developed to afford the corresponding primary amides in 22% to quantitative yields. Additionally, we have applied the amidation to the preparation of various amides containing hydroxamic acids and achieved the synthesis of (1S,2R)-tranylcypromine as an antidepressant medicine via Lossen rearrangement." @default.
- W2767920497 created "2017-11-17" @default.
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- W2767920497 date "2017-12-01" @default.
- W2767920497 modified "2023-09-27" @default.
- W2767920497 title "Amidation of carboxylic acids via the mixed carbonic carboxylic anhydrides and its application to synthesis of antidepressant (1 S ,2 R )-tranylcypromine" @default.
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- W2767920497 doi "https://doi.org/10.1016/j.tetasy.2017.10.015" @default.
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