FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767926248> ?p ?o ?g. }

• W2767926248 abstract "The pathophysiological mechanisms associated with the effects of red blood cell (RBC) transfusion on cardiopulmonary function and inflammation are unclear. We developed an experimental model of homologous 14-days stored RBC transfusion in hypovolemic swine to evaluate the short-term effects of transfusion on cardiopulmonary system and inflammation. Sixteen healthy male anesthetized swine (68±3.3 kg) were submitted to controlled hemorrhage (25% of blood volume). Two units of non-filtered RBC from each animal were stored under blood bank conditions for 14 days. After 30 min of hypovolemia, the control group (n=8) received an infusion of lactated Ringer's solution (three times the removed volume). The transfusion group (n=8) received two units of homologous 14-days stored RBC and lactated Ringer's solution in a volume that was three times the difference between blood removed and blood transfusion infused. Both groups were followed up for 6 h after resuscitation with collection of hemodynamic and respiratory data. Cytokines and RNA expression were measured in plasma and lung tissue. Stored RBC transfusion significantly increased mixed oxygen venous saturation and arterial oxygen content. Transfusion was not associated with alterations on pulmonary function. Pulmonary concentrations of cytokines were not different between groups. Gene expression for lung cytokines demonstrated a 2-fold increase in mRNA level for inducible nitric oxide synthase and a 0.5-fold decrease in mRNA content for IL-21 in the transfused group. Thus, stored homologous RBC transfusion in a hypovolemia model improved cardiovascular parameters but did not induce significant effects on microcirculation, pulmonary inflammation and respiratory function up to 6 h after transfusion." @default.
• W2767926248 created "2017-11-17" @default.
• W2767926248 creator A5018875616 @default.
• W2767926248 creator A5037340676 @default.
• W2767926248 creator A5058157534 @default.
• W2767926248 creator A5062710421 @default.
• W2767926248 creator A5063189986 @default.
• W2767926248 creator A5068779541 @default.
• W2767926248 creator A5076315451 @default.
• W2767926248 creator A5085571939 @default.
• W2767926248 date "2018-01-01" @default.
• W2767926248 modified "2023-09-27" @default.
• W2767926248 title "Short-term effects of stored homologous red blood cell transfusion on cardiorespiratory function and inflammation: an experimental study in a hypovolemia model" @default.
• W2767926248 cites W113938926 @default.
• W2767926248 cites W127034668 @default.
• W2767926248 cites W145544299 @default.
• W2767926248 cites W1482884942 @default.
• W2767926248 cites W1507285779 @default.
• W2767926248 cites W1552823499 @default.
• W2767926248 cites W1946955186 @default.
• W2767926248 cites W1947524168 @default.
• W2767926248 cites W1968311552 @default.
• W2767926248 cites W1972201793 @default.
• W2767926248 cites W1992912598 @default.
• W2767926248 cites W1996624977 @default.
• W2767926248 cites W1999948990 @default.
• W2767926248 cites W2002409723 @default.
• W2767926248 cites W2006581477 @default.
• W2767926248 cites W2023556803 @default.
• W2767926248 cites W2030027348 @default.
• W2767926248 cites W2040678834 @default.
• W2767926248 cites W2064637067 @default.
• W2767926248 cites W2085189986 @default.
• W2767926248 cites W2086221578 @default.
• W2767926248 cites W2088599858 @default.
• W2767926248 cites W2097930818 @default.
• W2767926248 cites W2103437475 @default.
• W2767926248 cites W2103551786 @default.
• W2767926248 cites W2104378195 @default.
• W2767926248 cites W2112108453 @default.
• W2767926248 cites W2131381192 @default.
• W2767926248 cites W2132785271 @default.
• W2767926248 cites W2145469936 @default.
• W2767926248 cites W2146140117 @default.
• W2767926248 cites W2149169816 @default.
• W2767926248 cites W2149872772 @default.
• W2767926248 cites W2155894751 @default.
• W2767926248 cites W2166768579 @default.
• W2767926248 cites W2315317814 @default.
• W2767926248 cites W2317501115 @default.
• W2767926248 cites W2508656056 @default.
• W2767926248 cites W2589218681 @default.
• W2767926248 doi "https://doi.org/10.1590/1414-431x20176258" @default.
• W2767926248 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5685056" @default.
• W2767926248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29185590" @default.
• W2767926248 hasPublicationYear "2018" @default.
• W2767926248 type Work @default.
• W2767926248 sameAs 2767926248 @default.
• W2767926248 citedByCount "3" @default.
• W2767926248 countsByYear W27679262482018 @default.
• W2767926248 countsByYear W27679262482019 @default.
• W2767926248 countsByYear W27679262482022 @default.
• W2767926248 crossrefType "journal-article" @default.
• W2767926248 hasAuthorship W2767926248A5018875616 @default.
• W2767926248 hasAuthorship W2767926248A5037340676 @default.
• W2767926248 hasAuthorship W2767926248A5058157534 @default.
• W2767926248 hasAuthorship W2767926248A5062710421 @default.
• W2767926248 hasAuthorship W2767926248A5063189986 @default.
• W2767926248 hasAuthorship W2767926248A5068779541 @default.
• W2767926248 hasAuthorship W2767926248A5076315451 @default.
• W2767926248 hasAuthorship W2767926248A5085571939 @default.
• W2767926248 hasBestOaLocation W27679262481 @default.
• W2767926248 hasConcept C126322002 @default.
• W2767926248 hasConcept C178853913 @default.
• W2767926248 hasConcept C203014093 @default.
• W2767926248 hasConcept C2776557347 @default.
• W2767926248 hasConcept C2778165595 @default.
• W2767926248 hasConcept C2778917026 @default.
• W2767926248 hasConcept C2780014101 @default.
• W2767926248 hasConcept C2781309813 @default.
• W2767926248 hasConcept C37557685 @default.
• W2767926248 hasConcept C42219234 @default.
• W2767926248 hasConcept C71924100 @default.
• W2767926248 hasConceptScore W2767926248C126322002 @default.
• W2767926248 hasConceptScore W2767926248C178853913 @default.
• W2767926248 hasConceptScore W2767926248C203014093 @default.
• W2767926248 hasConceptScore W2767926248C2776557347 @default.
• W2767926248 hasConceptScore W2767926248C2778165595 @default.
• W2767926248 hasConceptScore W2767926248C2778917026 @default.
• W2767926248 hasConceptScore W2767926248C2780014101 @default.
• W2767926248 hasConceptScore W2767926248C2781309813 @default.
• W2767926248 hasConceptScore W2767926248C37557685 @default.
• W2767926248 hasConceptScore W2767926248C42219234 @default.
• W2767926248 hasConceptScore W2767926248C71924100 @default.
• W2767926248 hasIssue "1" @default.
• W2767926248 hasLocation W27679262481 @default.
• W2767926248 hasLocation W27679262482 @default.
• W2767926248 hasLocation W27679262483 @default.
• W2767926248 hasLocation W27679262484 @default.
• W2767926248 hasLocation W27679262485 @default.

• next