Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767935219> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2767935219 endingPage "869" @default.
- W2767935219 startingPage "864" @default.
- W2767935219 abstract "DACT1, was first identified as a Dishevelled-associated antagonist of Wnt signaling pathway. It has been reported that DACT1 functions in embryonic development and tumorigenesis. However, the regulation of DACT1 still remains unclear. We found Wnt signaling has no effect on DACT1, but TGF-β increases expression of DACT1 in intestinal epithelial cells. In addition, the minimal promoter is located in the region of −500 bp to +1 bp and the region between −3000 bp to +1 bp enhanced promoter activity. Site-directed mutation analysis was performed and indicated that potential regulatory elements was near −335 bp. Our study provided the basic information for the exploration of DACT1 regulation and expression. Moreover, TGF-β inhibits Wnt signaling to enhance the function of DACT1 inhibiting Wnt signaling." @default.
- W2767935219 created "2017-11-17" @default.
- W2767935219 creator A5005228021 @default.
- W2767935219 creator A5007384450 @default.
- W2767935219 creator A5033904513 @default.
- W2767935219 creator A5054511459 @default.
- W2767935219 creator A5059234351 @default.
- W2767935219 creator A5088756989 @default.
- W2767935219 creator A5091822072 @default.
- W2767935219 date "2018-01-01" @default.
- W2767935219 modified "2023-10-18" @default.
- W2767935219 title "TGF-β signaling regulates DACT1 expression in intestinal epithelial cells" @default.
- W2767935219 cites W1972486801 @default.
- W2767935219 cites W1981556352 @default.
- W2767935219 cites W1987705498 @default.
- W2767935219 cites W1997582300 @default.
- W2767935219 cites W2000667825 @default.
- W2767935219 cites W2004627796 @default.
- W2767935219 cites W2005440429 @default.
- W2767935219 cites W2006419043 @default.
- W2767935219 cites W2017668082 @default.
- W2767935219 cites W2025744983 @default.
- W2767935219 cites W2048451929 @default.
- W2767935219 cites W2083943004 @default.
- W2767935219 cites W2086554912 @default.
- W2767935219 cites W2092344861 @default.
- W2767935219 cites W2102665272 @default.
- W2767935219 cites W2107648723 @default.
- W2767935219 cites W2121447250 @default.
- W2767935219 cites W2134133553 @default.
- W2767935219 cites W2144197789 @default.
- W2767935219 cites W2151582261 @default.
- W2767935219 cites W2155507705 @default.
- W2767935219 cites W4211030739 @default.
- W2767935219 cites W60009208 @default.
- W2767935219 doi "https://doi.org/10.1016/j.biopha.2017.11.017" @default.
- W2767935219 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29136762" @default.
- W2767935219 hasPublicationYear "2018" @default.
- W2767935219 type Work @default.
- W2767935219 sameAs 2767935219 @default.
- W2767935219 citedByCount "2" @default.
- W2767935219 countsByYear W27679352192020 @default.
- W2767935219 crossrefType "journal-article" @default.
- W2767935219 hasAuthorship W2767935219A5005228021 @default.
- W2767935219 hasAuthorship W2767935219A5007384450 @default.
- W2767935219 hasAuthorship W2767935219A5033904513 @default.
- W2767935219 hasAuthorship W2767935219A5054511459 @default.
- W2767935219 hasAuthorship W2767935219A5059234351 @default.
- W2767935219 hasAuthorship W2767935219A5088756989 @default.
- W2767935219 hasAuthorship W2767935219A5091822072 @default.
- W2767935219 hasConcept C104317684 @default.
- W2767935219 hasConcept C107300179 @default.
- W2767935219 hasConcept C137620995 @default.
- W2767935219 hasConcept C2775928862 @default.
- W2767935219 hasConcept C54355233 @default.
- W2767935219 hasConcept C555283112 @default.
- W2767935219 hasConcept C62478195 @default.
- W2767935219 hasConcept C86803240 @default.
- W2767935219 hasConcept C95444343 @default.
- W2767935219 hasConceptScore W2767935219C104317684 @default.
- W2767935219 hasConceptScore W2767935219C107300179 @default.
- W2767935219 hasConceptScore W2767935219C137620995 @default.
- W2767935219 hasConceptScore W2767935219C2775928862 @default.
- W2767935219 hasConceptScore W2767935219C54355233 @default.
- W2767935219 hasConceptScore W2767935219C555283112 @default.
- W2767935219 hasConceptScore W2767935219C62478195 @default.
- W2767935219 hasConceptScore W2767935219C86803240 @default.
- W2767935219 hasConceptScore W2767935219C95444343 @default.
- W2767935219 hasFunder F4320321001 @default.
- W2767935219 hasLocation W27679352191 @default.
- W2767935219 hasLocation W27679352192 @default.
- W2767935219 hasOpenAccess W2767935219 @default.
- W2767935219 hasPrimaryLocation W27679352191 @default.
- W2767935219 hasRelatedWork W1545602072 @default.
- W2767935219 hasRelatedWork W1981311091 @default.
- W2767935219 hasRelatedWork W1994979890 @default.
- W2767935219 hasRelatedWork W1997085708 @default.
- W2767935219 hasRelatedWork W2033984390 @default.
- W2767935219 hasRelatedWork W2054062221 @default.
- W2767935219 hasRelatedWork W2109767902 @default.
- W2767935219 hasRelatedWork W2152975437 @default.
- W2767935219 hasRelatedWork W2370215344 @default.
- W2767935219 hasRelatedWork W2966286774 @default.
- W2767935219 hasVolume "97" @default.
- W2767935219 isParatext "false" @default.
- W2767935219 isRetracted "false" @default.
- W2767935219 magId "2767935219" @default.
- W2767935219 workType "article" @default.