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- W2767939154 abstract "Background and objective: radioiodine treatment (I131) used to treat thyroid carcinomas produces side effects (sialadenitis, xerostomia, dysphagia and caries susceptibility) reflecting in a poor patient quality of life. This study aimed to evaluate the effect of I131 on salivary function and possible oral impairment.Material and methods: Thirty-seven patients undergoing I131 were submitted to oral examination, answer questions regarding xerostomia/hyposalivation and collect saliva at three moments (M1: 30–45 days before I131, M2: 1–2 days after I131 and M3: 7–10 days after treatment). Saliva was assayed for flow rate and calcium/phosphate concentrations.Results and conclusions: significant difference in calcium/phosphate concentration was shown between M1 and M2, with evident decrease at M2. Flow rate reduced right after treatment with 41% of patients returning to previous rate at M3 (no statistical difference). A higher number of patients related xerostomia and difficulty in swallowing food at M2. The results showed that xerostomia/hyposalivation, dysphagia and calcium/phosphate concentration decrease may be considered early radioiodine side effects." @default.
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- W2767939154 date "2017-11-10" @default.
- W2767939154 modified "2023-10-14" @default.
- W2767939154 title "Salivary evaluation in radioactive I<sup>131</sup> treated patients with thyroid carcinoma" @default.
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- W2767939154 doi "https://doi.org/10.1080/00016357.2017.1399214" @default.
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