FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2767966175> ?p ?o ?g. }

• W2767966175 endingPage "109" @default.
• W2767966175 startingPage "98" @default.
• W2767966175 abstract "Abdominal aortic aneurysms (AAA) are localized, commonly-occurring dilations of the aorta. When equilibrium between blood pressure (loading) and wall mechanical resistance is lost, rupture ensues, and patient death follows, if not treated immediately. Experimental and numerical analyses of flow patterns in arteries show direct correlations between wall shear stress and wall mechano-adaptation with the development of zones prone to thrombus formation. For further insights into AAA flow topology/growth interaction, a workout of patient-specific computational flow dynamics (CFD) is proposed to compute finite-time Lyapunov exponents and extract Lagrangian-coherent structures (LCS). This computational model was first compared with 4-D phase-contrast magnetic resonance imaging (MRI) in 5 patients. To better understand the impact of flow topology and transport on AAA growth, hyperbolic, repelling LCS were computed in 1 patient during 8-year follow-up, including 9 volumetric morphologic AAA measures by computed tomography-angiography (CTA). LCS defined barriers to Lagrangian jet cores entering AAA. Domains enclosed between LCS and the aortic wall were considered to be stagnation zones. Their evolution was studied during AAA growth. Good correlation – 2-D cross-correlation coefficients of 0.65, 0.86 and 0.082 (min, max, SD) – was obtained between numerical simulations and 4-D MRI acquisitions in 6 specific cross-sections from 4 patients. In follow-up study, LCS divided AAA lumens into 3 dynamically-isolated zones: 2 stagnation volumes lying in dilated portions of the AAA, and circulating volume connecting the inlet to the outlet. The volume of each zone was tracked over time. Although circulating volume remained unchanged during 8-year follow-up, the AAA lumen and main stagnation zones grew significantly (8 cm3/year and 6 cm3/year, respectively). This study reveals that transient transport topology can be quantified in patient-specific AAA during disease progression by CTA, in parallel with lumen morphology. It is anticipated that analysis of the main AAA stagnation zones by patient-specific CFD on a yearly basis could help to predict AAA growth and rupture." @default.
• W2767966175 created "2017-11-17" @default.
• W2767966175 creator A5004717775 @default.
• W2767966175 creator A5006349086 @default.
• W2767966175 creator A5039663825 @default.
• W2767966175 creator A5074561197 @default.
• W2767966175 creator A5091397892 @default.
• W2767966175 date "2018-01-01" @default.
• W2767966175 modified "2023-09-30" @default.
• W2767966175 title "Flow stagnation volume and abdominal aortic aneurysm growth: Insights from patient-specific computational flow dynamics of Lagrangian-coherent structures" @default.
• W2767966175 cites W1535417994 @default.
• W2767966175 cites W1568514806 @default.
• W2767966175 cites W1571161907 @default.
• W2767966175 cites W1772369914 @default.
• W2767966175 cites W1966652592 @default.
• W2767966175 cites W1968807133 @default.
• W2767966175 cites W1969597151 @default.
• W2767966175 cites W1976503053 @default.
• W2767966175 cites W1980020427 @default.
• W2767966175 cites W1980535874 @default.
• W2767966175 cites W1981075633 @default.
• W2767966175 cites W1984587485 @default.
• W2767966175 cites W1986005875 @default.
• W2767966175 cites W1986447971 @default.
• W2767966175 cites W1996417339 @default.
• W2767966175 cites W1999431413 @default.
• W2767966175 cites W2000831039 @default.
• W2767966175 cites W2012190262 @default.
• W2767966175 cites W2012611439 @default.
• W2767966175 cites W2014219950 @default.
• W2767966175 cites W2015263684 @default.
• W2767966175 cites W2020212963 @default.
• W2767966175 cites W2024192061 @default.
• W2767966175 cites W2030734358 @default.
• W2767966175 cites W2033426063 @default.
• W2767966175 cites W2033518278 @default.
• W2767966175 cites W2033920059 @default.
• W2767966175 cites W2038828978 @default.
• W2767966175 cites W2039931668 @default.
• W2767966175 cites W2041556523 @default.
• W2767966175 cites W2050371288 @default.
• W2767966175 cites W2053641596 @default.
• W2767966175 cites W2054151939 @default.
• W2767966175 cites W2059716814 @default.
• W2767966175 cites W2062736686 @default.
• W2767966175 cites W2080695099 @default.
• W2767966175 cites W2084755618 @default.
• W2767966175 cites W2086347968 @default.
• W2767966175 cites W2091803576 @default.
• W2767966175 cites W2093794292 @default.
• W2767966175 cites W2099167181 @default.
• W2767966175 cites W2102406793 @default.
• W2767966175 cites W2102942151 @default.
• W2767966175 cites W2104366157 @default.
• W2767966175 cites W2107847621 @default.
• W2767966175 cites W2110347179 @default.
• W2767966175 cites W2118386984 @default.
• W2767966175 cites W2118951490 @default.
• W2767966175 cites W2122424119 @default.
• W2767966175 cites W2123402149 @default.
• W2767966175 cites W2125220309 @default.
• W2767966175 cites W2126212536 @default.
• W2767966175 cites W2126476406 @default.
• W2767966175 cites W2127890285 @default.
• W2767966175 cites W2146132623 @default.
• W2767966175 cites W2150850864 @default.
• W2767966175 cites W2154520046 @default.
• W2767966175 cites W2164274616 @default.
• W2767966175 cites W2179397665 @default.
• W2767966175 cites W2311257432 @default.
• W2767966175 cites W2401399410 @default.
• W2767966175 cites W299983275 @default.
• W2767966175 cites W3102889263 @default.
• W2767966175 doi "https://doi.org/10.1016/j.compbiomed.2017.10.033" @default.
• W2767966175 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29169074" @default.
• W2767966175 hasPublicationYear "2018" @default.
• W2767966175 type Work @default.
• W2767966175 sameAs 2767966175 @default.
• W2767966175 citedByCount "27" @default.
• W2767966175 countsByYear W27679661752018 @default.
• W2767966175 countsByYear W27679661752019 @default.
• W2767966175 countsByYear W27679661752020 @default.
• W2767966175 countsByYear W27679661752021 @default.
• W2767966175 countsByYear W27679661752022 @default.
• W2767966175 countsByYear W27679661752023 @default.
• W2767966175 crossrefType "journal-article" @default.
• W2767966175 hasAuthorship W2767966175A5004717775 @default.
• W2767966175 hasAuthorship W2767966175A5006349086 @default.
• W2767966175 hasAuthorship W2767966175A5039663825 @default.
• W2767966175 hasAuthorship W2767966175A5074561197 @default.
• W2767966175 hasAuthorship W2767966175A5091397892 @default.
• W2767966175 hasConcept C121332964 @default.
• W2767966175 hasConcept C126838900 @default.
• W2767966175 hasConcept C143409427 @default.
• W2767966175 hasConcept C158622935 @default.
• W2767966175 hasConcept C158846371 @default.
• W2767966175 hasConcept C1633027 @default.
• W2767966175 hasConcept C164705383 @default.

• next