FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2768049771> ?p ?o ?g. }

• W2768049771 endingPage "492" @default.
• W2768049771 startingPage "485" @default.
• W2768049771 abstract "The use of contrast enhanced ultrasound (CEUS) for the diagnosis of hepatocellular carcinoma (HCC) in cirrhosis was questioned because of the risk of a false positive diagnosis in cases of cholangiocarcinoma. The American College of Radiology has recently released a scheme (CEUS Liver Imaging Reporting and Data System [LI-RADS®]) to classify lesions at risk of HCC investigated by CEUS. The aim of the present study was to validate this LI-RADS scheme for the diagnosis of HCC.A total of 1,006 nodules from 848 patients with chronic liver disease at risk of HCC were collected in five Italian centers and retrospectively analyzed. Nodules were classified as LR-5, (HCC) if ≥1 cm with arterial phase hyperenhancement, and late washout (onset ≥60 s after contrast injection) of mild degree. Rim enhancement and/or early and/or marked washout qualified lesions as LR-M (malignant, but not specific for HCC). Other combinations qualified lesions at intermediate risk for HCC (LR-3) or probable HCC (LR-4). Diagnostic reference standard was CT/MRI diagnosis of HCC (n = 506) or histology (n = 500).The median nodule size was 2 cm. Of 1,006 nodules, 820 (81%) were HCC, 40 (4%) were cholangiocarcinoma, 116 (11%) regenerative nodules (±dysplastic). The LR-5 category (52% of all nodules) was 98.5% predictive of HCC, with no risk of misdiagnosis for pure cholangiocarcinoma. Sensitivity for HCC was 62%. All LR-M nodules were malignant and the majority of non-hepatocellular origin. Over 75% of cholangiocarcinomas were LR-M. The LR-3 category included 203 lesions (HCC 96 [47%]) and the LR-4 202 (HCC 173 [87%]).The CEUS LI-RADS class LR-5 is highly specific for HCC, enabling its use for a confident non-invasive diagnosis.This is a retrospective study of approximately 1,000 focal lesions at risk for hepatocellular carcinoma (HCC). Herein, we demonstrate that the refined definition of the typical contrast enhanced ultrasound pattern of HCC introduced by the Liver Imaging Reporting and Data System (LI-RADS®) practically abolishes the risk of misdiagnosis of other malignant entities (e.g. cholangiocarcinoma) for HCC with negligible reduction in sensitivity. These data support the use of contrast enhanced ultrasound to diagnose HCC in cirrhosis." @default.
• W2768049771 created "2017-11-17" @default.
• W2768049771 creator A5008646170 @default.
• W2768049771 creator A5017197765 @default.
• W2768049771 creator A5017429993 @default.
• W2768049771 creator A5018377091 @default.
• W2768049771 creator A5026656497 @default.
• W2768049771 creator A5026985433 @default.
• W2768049771 creator A5028450214 @default.
• W2768049771 creator A5029721718 @default.
• W2768049771 creator A5032561046 @default.
• W2768049771 creator A5032593836 @default.
• W2768049771 creator A5032982792 @default.
• W2768049771 creator A5045406649 @default.
• W2768049771 creator A5048376360 @default.
• W2768049771 creator A5050839784 @default.
• W2768049771 creator A5059027212 @default.
• W2768049771 creator A5065815596 @default.
• W2768049771 creator A5075307308 @default.
• W2768049771 creator A5075654303 @default.
• W2768049771 creator A5076471646 @default.
• W2768049771 creator A5079291775 @default.
• W2768049771 creator A5079476272 @default.
• W2768049771 creator A5084284369 @default.
• W2768049771 creator A5084975806 @default.
• W2768049771 creator A5088654582 @default.
• W2768049771 creator A5091284981 @default.
• W2768049771 date "2018-03-01" @default.
• W2768049771 modified "2023-10-17" @default.
• W2768049771 title "Contrast ultrasound LI-RADS LR-5 identifies hepatocellular carcinoma in cirrhosis in a multicenter restropective study of 1,006 nodules" @default.
• W2768049771 cites W1814665428 @default.
• W2768049771 cites W1964829819 @default.
• W2768049771 cites W1965636008 @default.
• W2768049771 cites W1967541992 @default.
• W2768049771 cites W1982586653 @default.
• W2768049771 cites W2002021865 @default.
• W2768049771 cites W2006777132 @default.
• W2768049771 cites W2014774747 @default.
• W2768049771 cites W2044305759 @default.
• W2768049771 cites W2047261154 @default.
• W2768049771 cites W2047554241 @default.
• W2768049771 cites W2051299102 @default.
• W2768049771 cites W2075599744 @default.
• W2768049771 cites W2082329290 @default.
• W2768049771 cites W2089957623 @default.
• W2768049771 cites W2094785364 @default.
• W2768049771 cites W2099677809 @default.
• W2768049771 cites W2106307128 @default.
• W2768049771 cites W2128551196 @default.
• W2768049771 cites W2130325374 @default.
• W2768049771 cites W2138508705 @default.
• W2768049771 cites W2146494182 @default.
• W2768049771 cites W2155592152 @default.
• W2768049771 cites W2163403599 @default.
• W2768049771 cites W2163486683 @default.
• W2768049771 cites W2224433857 @default.
• W2768049771 cites W2265353509 @default.
• W2768049771 cites W2295616892 @default.
• W2768049771 cites W2303636495 @default.
• W2768049771 cites W2317852051 @default.
• W2768049771 cites W2591927678 @default.
• W2768049771 cites W4238060005 @default.
• W2768049771 cites W4245784696 @default.
• W2768049771 cites W71782267 @default.
• W2768049771 doi "https://doi.org/10.1016/j.jhep.2017.11.007" @default.
• W2768049771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29133247" @default.
• W2768049771 hasPublicationYear "2018" @default.
• W2768049771 type Work @default.
• W2768049771 sameAs 2768049771 @default.
• W2768049771 citedByCount "179" @default.
• W2768049771 countsByYear W27680497712018 @default.
• W2768049771 countsByYear W27680497712019 @default.
• W2768049771 countsByYear W27680497712020 @default.
• W2768049771 countsByYear W27680497712021 @default.
• W2768049771 countsByYear W27680497712022 @default.
• W2768049771 countsByYear W27680497712023 @default.
• W2768049771 crossrefType "journal-article" @default.
• W2768049771 hasAuthorship W2768049771A5008646170 @default.
• W2768049771 hasAuthorship W2768049771A5017197765 @default.
• W2768049771 hasAuthorship W2768049771A5017429993 @default.
• W2768049771 hasAuthorship W2768049771A5018377091 @default.
• W2768049771 hasAuthorship W2768049771A5026656497 @default.
• W2768049771 hasAuthorship W2768049771A5026985433 @default.
• W2768049771 hasAuthorship W2768049771A5028450214 @default.
• W2768049771 hasAuthorship W2768049771A5029721718 @default.
• W2768049771 hasAuthorship W2768049771A5032561046 @default.
• W2768049771 hasAuthorship W2768049771A5032593836 @default.
• W2768049771 hasAuthorship W2768049771A5032982792 @default.
• W2768049771 hasAuthorship W2768049771A5045406649 @default.
• W2768049771 hasAuthorship W2768049771A5048376360 @default.
• W2768049771 hasAuthorship W2768049771A5050839784 @default.
• W2768049771 hasAuthorship W2768049771A5059027212 @default.
• W2768049771 hasAuthorship W2768049771A5065815596 @default.
• W2768049771 hasAuthorship W2768049771A5075307308 @default.
• W2768049771 hasAuthorship W2768049771A5075654303 @default.
• W2768049771 hasAuthorship W2768049771A5076471646 @default.
• W2768049771 hasAuthorship W2768049771A5079291775 @default.
• W2768049771 hasAuthorship W2768049771A5079476272 @default.

• next