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- W2768052105 abstract "Myclobutanil is currently used on the flowering plants. Little is known about how Apis cerana cerana respond to myclobutanil exposure. Hence, the acute toxicity of myclobutanil and its sublethal effects on respiration, flight and detoxification enzymes [7-ethoxycoumarin O-deethylase (ECOD) and glutathione S-transferases (GSTs)] in A. cerana cerana were investigated. The results indicated that formulation grade myclobutanil showed moderate toxicity to A. cerana cerana either contact (LD50 = 4.697 μg/bee) or oral (LD50 = 2.154 μg/bee) exposure. Sublethal dose of myclobutanil significantly reduced the respiration rate of workers at 24 h and 48 h regardless of the exposure method. However, myclobutanil didn't significantly affect the take-off flight. After nurse bees exposure to the dose (LD5) of formulation-grade myclobutanil, ECOD activity was significantly induced when compared with control, but GST activity didn't change. In the forager bees, no enzyme markers response was obtained in this test. From the present study we can infer that myclobutanil disturb respiration and P450-mediated detoxification of the individual bees of A. cerana cerana. Thus, myclobutanil may has risk for A. cerana cerana, it should be cautiously used." @default.
- W2768052105 created "2017-11-17" @default.
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- W2768052105 date "2018-05-01" @default.
- W2768052105 modified "2023-10-10" @default.
- W2768052105 title "Acute toxicity and sublethal effects of myclobutanil on respiration, flight and detoxification enzymes in Apis cerana cerana" @default.
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- W2768052105 doi "https://doi.org/10.1016/j.pestbp.2017.11.001" @default.
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