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• W2768125059 abstract "The first chapter introduces basics of nervous system development. We start with the vertebrate-characteristic morphogenetic event of neurulation. This process leads to the internalized neural tube that forms the entire central nervous system (CNS). In parallel, the formation of neural crest and ectodermal thickenings called placodes develop into the peripheral nervous system and the majority of head sense organs. The neural tube comprises the proliferative neuroepithelium that exclusively produces all neural cell types of brain and spinal cord (including neurons, astro-, and oligodendroglia). Subsequently, neurogenetic processes such as neural proliferation, determination, and differentiation take place within the neural tube wall. In general, these neurogenetic processes include radial migration of neuronal precursors from periventricular to subpial sites. The theoretical framework of the prosomeric model explains emerging neuroanatomical differences along dorsoventral and anteroposterior central nervous axes. Furthermore, the chapter highlights the specific development of the mammalian isocortex, cerebellum, and thalamus with a focus on inside-out versus outside-in patterns of cortex formation/tangential migration events. Finally, it addresses primary (embryonic) and secondary (larval) zebrafish neurogenesis" @default.
• W2768125059 created "2017-12-04" @default.
• W2768125059 creator A5022846156 @default.
• W2768125059 creator A5045190731 @default.
• W2768125059 date "2016-01-01" @default.
• W2768125059 modified "2023-10-16" @default.
• W2768125059 title "Vertebrate Central Nervous System Development" @default.
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