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• W2768338835 abstract "Aim: The aim of this study was to explore the relationship between IL-1β-31T/C polymorphism and serum levels of IL-1β and the risk of acute heart failure (AHF). Methods: A total of 320 dyspnea patients (160 with AHF and 160 without AHF) and 100 healthy subjects were included in this study. IL-1β genotyping was performed by PCR-restriction fragment length polymorphism technique. Results: Concentration of IL-1β was significantly higher in patients with heart failure (HF) compared with non-HF and control groups. Results of the distribution of IL-1β-31T/C genotypes and allele frequencies did not show any significant difference between the three groups. Serum levels of IL-1β were found to be higher among TT genotype than TC and CC genotype. Conclusion: IL-1β levels may be useful for the evaluation of diagnosis in acutely decompensated HF." @default.
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• W2768338835 date "2017-12-01" @default.
• W2768338835 modified "2023-09-27" @default.
• W2768338835 title "<i>IL-1β</i> gene polymorphism and serum levels in a Tunisian population with acute heart failure" @default.
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• W2768338835 doi "https://doi.org/10.2217/bmm-2017-0179" @default.
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