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- W2768360015 abstract "Endometrial scratching is an intentional injury performed to the mucosal lining of the uterus to enhance pregnancy outcome. The biological pathways by which such a procedure might increase pregnancy are not fully understood. Experimental evidence points to an altered gene expression and inflow of particular populations of immune cells following injury, but there is yet no hard proof that these changes are actually facilitating pregnancy. Clinical evidence to support the procedure in fertility patients with recurrent implantation failure is still quite weak and requires further well-designed studies to demonstrate a beneficial effect. Adverse effects of the procedure are pain and bleeding. At this moment, there are insufficient data to support endometrial scratching as standard of care. The procedure should thus be limited to the setting of clinical trials, until further evidence of utility in standard patient care." @default.
- W2768360015 created "2017-12-04" @default.
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- W2768360015 date "2018-01-01" @default.
- W2768360015 modified "2023-09-24" @default.
- W2768360015 title "The Endometrium: Scratching" @default.
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- W2768360015 doi "https://doi.org/10.1016/b978-0-12-801238-3.64877-8" @default.
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