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- W2768372215 abstract "Bone tissue engineering strategies utilize biodegradable polymeric matrices alone or in combination with cells and factors to provide mechanical support to bone, while promoting cell proliferation, differentiation, and tissue ingrowth. The performance of mechanically competent, micro-nanostructured polymeric matrices, in combination with bone marrow stromal cells (BMSCs), is evaluated in a critical sized bone defect. Cellulose acetate (CA) is used to fabricate a porous microstructured matrix. Type I collagen is then allowed to self-assemble on these microstructures to create a natural polymer-based, micro-nanostructured matrix (CAc). Poly (lactic-co-glycolic acid) matrices with identical microstructures serve as controls. Significantly higher number of implanted host cells are distributed in the natural polymer based micro-nanostructures with greater bone density and more uniform cell distribution. Additionally, a twofold increase in collagen content is observed with natural polymer based scaffolds. This study establishes the benefits of natural polymer derived micro-nanostructures in combination with donor derived BMSCs to repair and regenerate critical sized bone defects. Natural polymer based materials with mechanically competent micro-nanostructures may serve as an alternative material platform for bone regeneration." @default.
- W2768372215 created "2017-12-04" @default.
- W2768372215 creator A5022528290 @default.
- W2768372215 creator A5040180930 @default.
- W2768372215 creator A5041260299 @default.
- W2768372215 creator A5047640338 @default.
- W2768372215 creator A5062658027 @default.
- W2768372215 date "2017-11-27" @default.
- W2768372215 modified "2023-10-18" @default.
- W2768372215 title "Micro‐Nanostructures of Cellulose‐Collagen for Critical Sized Bone Defect Healing" @default.
- W2768372215 cites W1534731743 @default.
- W2768372215 cites W1535485604 @default.
- W2768372215 cites W1593555249 @default.
- W2768372215 cites W1599494694 @default.
- W2768372215 cites W164136508 @default.
- W2768372215 cites W1897577213 @default.
- W2768372215 cites W1965311433 @default.
- W2768372215 cites W1967212772 @default.
- W2768372215 cites W1968882409 @default.
- W2768372215 cites W1969223773 @default.
- W2768372215 cites W1987349642 @default.
- W2768372215 cites W1989742166 @default.
- W2768372215 cites W1992801092 @default.
- W2768372215 cites W1998650056 @default.
- W2768372215 cites W1998905931 @default.
- W2768372215 cites W2001380203 @default.
- W2768372215 cites W2007310752 @default.
- W2768372215 cites W2009391852 @default.
- W2768372215 cites W2010824264 @default.
- W2768372215 cites W2015979204 @default.
- W2768372215 cites W2021465534 @default.
- W2768372215 cites W2021773986 @default.
- W2768372215 cites W2022346732 @default.
- W2768372215 cites W2022436387 @default.
- W2768372215 cites W2023680421 @default.
- W2768372215 cites W2026162083 @default.
- W2768372215 cites W2027725351 @default.
- W2768372215 cites W2030922043 @default.
- W2768372215 cites W2031158924 @default.
- W2768372215 cites W2032342275 @default.
- W2768372215 cites W2032740145 @default.
- W2768372215 cites W2037176615 @default.
- W2768372215 cites W2037810763 @default.
- W2768372215 cites W2038426825 @default.
- W2768372215 cites W2039600788 @default.
- W2768372215 cites W2045584751 @default.
- W2768372215 cites W2045927948 @default.
- W2768372215 cites W2048859871 @default.
- W2768372215 cites W2048890220 @default.
- W2768372215 cites W2049491735 @default.
- W2768372215 cites W2050659938 @default.
- W2768372215 cites W2050875646 @default.
- W2768372215 cites W2051922866 @default.
- W2768372215 cites W2053865047 @default.
- W2768372215 cites W2057603010 @default.
- W2768372215 cites W2064999317 @default.
- W2768372215 cites W2065168307 @default.
- W2768372215 cites W2066533176 @default.
- W2768372215 cites W2070275078 @default.
- W2768372215 cites W2071913484 @default.
- W2768372215 cites W2073126451 @default.
- W2768372215 cites W2079051405 @default.
- W2768372215 cites W2080054593 @default.
- W2768372215 cites W2080805333 @default.
- W2768372215 cites W2083895495 @default.
- W2768372215 cites W2088667304 @default.
- W2768372215 cites W2091526175 @default.
- W2768372215 cites W2093648283 @default.
- W2768372215 cites W2094667694 @default.
- W2768372215 cites W2097111022 @default.
- W2768372215 cites W2106035984 @default.
- W2768372215 cites W2110194677 @default.
- W2768372215 cites W2111469399 @default.
- W2768372215 cites W2118598516 @default.
- W2768372215 cites W2124396531 @default.
- W2768372215 cites W2130173998 @default.
- W2768372215 cites W2130606072 @default.
- W2768372215 cites W2132551393 @default.
- W2768372215 cites W2134208433 @default.
- W2768372215 cites W2139776494 @default.
- W2768372215 cites W2140812435 @default.
- W2768372215 cites W2147086022 @default.
- W2768372215 cites W2153139452 @default.
- W2768372215 cites W2153182002 @default.
- W2768372215 cites W2154421213 @default.
- W2768372215 cites W2156280902 @default.
- W2768372215 cites W2160609918 @default.
- W2768372215 cites W2161162374 @default.
- W2768372215 cites W2163691864 @default.
- W2768372215 cites W2164833748 @default.
- W2768372215 cites W2165673443 @default.
- W2768372215 cites W2182017026 @default.
- W2768372215 cites W2199338994 @default.
- W2768372215 cites W2303933008 @default.
- W2768372215 cites W2354447813 @default.
- W2768372215 cites W2476542314 @default.
- W2768372215 cites W2508255960 @default.
- W2768372215 cites W2562035818 @default.
- W2768372215 cites W2986912763 @default.
- W2768372215 cites W4213141530 @default.