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- W2768429768 abstract "An abnormally high serum PSA is still the most frequent trigger for men to enter a suspected prostate cancer diagnostic pathway. Large prostates, especially the ones with a volume over 100 cc, are commonly associated with elevated PSA levels. In men with benign prostatic hyperplasia (BPH), PSA tends to increase over time, something that also occurs in men with untreated progressive prostate cancer. These two factors lead to frequent and unnecessary referrals of men with large prostates to suspected prostate cancer pathways. Many PSA derivatives and risk stratification tools have been developed in an attempt to overcome the limitations of total serum PSA and more accurately predict which men should have prostate biopsies, but translation into routine clinical practice has been hindered." @default.
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- W2768429768 date "2017-08-25" @default.
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- W2768429768 title "Management of an Elevated PSA and Biopsy Strategies in the Large Prostate" @default.
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- W2768429768 doi "https://doi.org/10.1007/978-3-319-64704-3_4" @default.
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