FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2768639046> ?p ?o ?g. }

• W2768639046 endingPage "425" @default.
• W2768639046 startingPage "420" @default.
• W2768639046 abstract "Background and purpose Multimodal tissue characterization by combined MRI and PET has high clinical potential in the context of sub-target definition for dose painting and response assessment but its clinical exploration is yet limited. The aim of this study was to prove the potential and feasibility of hybrid PET/MRI to non-invasively measure tumor hypoxia, perfusion and microstructure at one stop in tumors of the uterine cervix during chemoradiotherapy. Material and methods Ten cervix cancer patients were subjected to simultaneous multiparametric PET/MRI with [18F]fluoromisonidazole ([18F]FMISO). Imaging was scheduled before, twice during and after chemoradiotherapy. Intra- and inter-time point analyses of the extracted parameters (i.e. ADC, Ktrans, ABrix, [18F]FMISO-tumor to background ratio (TBR)) were performed. The [18F]FMISO uptake- and ADC-spatio-temporal changes were assessed. Results Patient averaged ADC values increased from baseline to follow up (1.03 ± 0.11/1.30 ± 0.13 × 10−3 mm2/s), while the TBR decreased (1.73 ± 0.24/1.36 ± 0.19), Ktrans dropped over time (0.17 ± 0.05/0.05 ± 0.05 min−1); for all above p < 0.05. None of these parameters correlated significantly on a voxel-by-voxel basis. Low-ADC regions spatially varied over time. There was pronounced reduction of the [18F]FMISO-avid volumes during treatment. Conclusions The suggested hybrid PET/MRI protocol to non-invasively investigate tumor hypoxia, perfusion and microstructure at one stop was feasible, revealing spatio-temporal response patterns that could be utilized for comprehensive sub-target definition for dose painting and response assessment." @default.
• W2768639046 created "2017-12-04" @default.
• W2768639046 creator A5000944221 @default.
• W2768639046 creator A5005480071 @default.
• W2768639046 creator A5013701975 @default.
• W2768639046 creator A5021925904 @default.
• W2768639046 creator A5026866600 @default.
• W2768639046 creator A5046807922 @default.
• W2768639046 creator A5047127804 @default.
• W2768639046 creator A5057349369 @default.
• W2768639046 creator A5059857128 @default.
• W2768639046 creator A5067216360 @default.
• W2768639046 creator A5070589073 @default.
• W2768639046 creator A5077820862 @default.
• W2768639046 date "2017-12-01" @default.
• W2768639046 modified "2023-09-30" @default.
• W2768639046 title "Impact of hybrid PET/MR technology on multiparametric imaging and treatment response assessment of cervix cancer" @default.
• W2768639046 cites W1480285586 @default.
• W2768639046 cites W1542150947 @default.
• W2768639046 cites W1834986685 @default.
• W2768639046 cites W1989754332 @default.
• W2768639046 cites W1997080950 @default.
• W2768639046 cites W2004271709 @default.
• W2768639046 cites W2012401759 @default.
• W2768639046 cites W2013436421 @default.
• W2768639046 cites W2027652813 @default.
• W2768639046 cites W2034269086 @default.
• W2768639046 cites W2036622441 @default.
• W2768639046 cites W2042098439 @default.
• W2768639046 cites W2048047781 @default.
• W2768639046 cites W2052760181 @default.
• W2768639046 cites W2060380449 @default.
• W2768639046 cites W2060496556 @default.
• W2768639046 cites W2079188072 @default.
• W2768639046 cites W2085956509 @default.
• W2768639046 cites W2086615166 @default.
• W2768639046 cites W2089456163 @default.
• W2768639046 cites W2094387623 @default.
• W2768639046 cites W2118419321 @default.
• W2768639046 cites W2124496728 @default.
• W2768639046 cites W2134637206 @default.
• W2768639046 cites W2151077579 @default.
• W2768639046 cites W2170427893 @default.
• W2768639046 cites W2268449860 @default.
• W2768639046 cites W2277238452 @default.
• W2768639046 cites W2285274600 @default.
• W2768639046 cites W2309318160 @default.
• W2768639046 cites W2356489615 @default.
• W2768639046 cites W2359525254 @default.
• W2768639046 cites W2412147901 @default.
• W2768639046 cites W2507863993 @default.
• W2768639046 cites W2513418461 @default.
• W2768639046 cites W2591574963 @default.
• W2768639046 cites W2599160637 @default.
• W2768639046 cites W2604531311 @default.
• W2768639046 doi "https://doi.org/10.1016/j.radonc.2017.10.036" @default.
• W2768639046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29153465" @default.
• W2768639046 hasPublicationYear "2017" @default.
• W2768639046 type Work @default.
• W2768639046 sameAs 2768639046 @default.
• W2768639046 citedByCount "23" @default.
• W2768639046 countsByYear W27686390462017 @default.
• W2768639046 countsByYear W27686390462018 @default.
• W2768639046 countsByYear W27686390462019 @default.
• W2768639046 countsByYear W27686390462020 @default.
• W2768639046 countsByYear W27686390462021 @default.
• W2768639046 countsByYear W27686390462022 @default.
• W2768639046 countsByYear W27686390462023 @default.
• W2768639046 crossrefType "journal-article" @default.
• W2768639046 hasAuthorship W2768639046A5000944221 @default.
• W2768639046 hasAuthorship W2768639046A5005480071 @default.
• W2768639046 hasAuthorship W2768639046A5013701975 @default.
• W2768639046 hasAuthorship W2768639046A5021925904 @default.
• W2768639046 hasAuthorship W2768639046A5026866600 @default.
• W2768639046 hasAuthorship W2768639046A5046807922 @default.
• W2768639046 hasAuthorship W2768639046A5047127804 @default.
• W2768639046 hasAuthorship W2768639046A5057349369 @default.
• W2768639046 hasAuthorship W2768639046A5059857128 @default.
• W2768639046 hasAuthorship W2768639046A5067216360 @default.
• W2768639046 hasAuthorship W2768639046A5070589073 @default.
• W2768639046 hasAuthorship W2768639046A5077820862 @default.
• W2768639046 hasConcept C121608353 @default.
• W2768639046 hasConcept C126322002 @default.
• W2768639046 hasConcept C126838900 @default.
• W2768639046 hasConcept C143409427 @default.
• W2768639046 hasConcept C146957229 @default.
• W2768639046 hasConcept C151730666 @default.
• W2768639046 hasConcept C2775842073 @default.
• W2768639046 hasConcept C2777740455 @default.
• W2768639046 hasConcept C2778424827 @default.
• W2768639046 hasConcept C2779081379 @default.
• W2768639046 hasConcept C2779343474 @default.
• W2768639046 hasConcept C2989005 @default.
• W2768639046 hasConcept C3017724952 @default.
• W2768639046 hasConcept C509974204 @default.
• W2768639046 hasConcept C54170458 @default.
• W2768639046 hasConcept C71924100 @default.
• W2768639046 hasConcept C86803240 @default.

• next