FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2768868841> ?p ?o ?g. }

• W2768868841 endingPage "205" @default.
• W2768868841 startingPage "199" @default.
• W2768868841 abstract "Dolutegravir may inhibit creatinine transporters in renal tubules and elevate serum creatinine levels. We investigated the usefulness of glomerular filtration rate (GFR) measured using inulin clearance (Cin), creatinine clearance (Ccr), and estimated GFR based on both serum creatinine (eGFRcre) and serum cystatin C (eGFRcys).HIV-1-infected Japanese patients with suppressed viremia and whose antiretroviral drug was switched to dolutegravir from other drugs were included (n = 108, Study 1). We compared eGFRcre and eGFRcys at the start and after 48 weeks of dolutegravir administration. For the patients providing consent, we measured Cin and Ccr (n = 15, Study 2). We assessed biases and accuracy and compared Cin with eGFRcre, eGFRcys, and Ccr.There were no differences in serum cystatin C and eGFRcys between baseline and at 48 weeks. Moreover, eGFRcre was significantly less accurate (within 30% of measured GFR) than both eGFRcys and Ccr (40% accuracy compared to 93% and 93%, respectively). eGFRcys was significantly less biased than eGFRcre and Ccr (p < 0.0001, p = 0.00036, respectively). No significant difference between Cin and eGFRcys was observed. eGFRcys was significantly correlated with Cin (γ = 0.85, p < 0.0001).eGFRcys provided the most precise estimate and most closely approximate Cin in HIV-1-infected Japanese patients with suppressed viremia treated with dolutegravir. We demonstrated clinical benefits of inulin clearance and eGFRcys. This is the first study performing inulin clearance for HIV-1-infected individuals and to show data for eGFRcys from a large cohort following a switch to dolutegravir from other antiretroviral agents." @default.
• W2768868841 created "2017-12-04" @default.
• W2768868841 creator A5014351560 @default.
• W2768868841 creator A5045763682 @default.
• W2768868841 creator A5051167036 @default.
• W2768868841 creator A5057822621 @default.
• W2768868841 date "2018-03-01" @default.
• W2768868841 modified "2023-10-16" @default.
• W2768868841 title "Clinical benefits of using inulin clearance and cystatin C for determining glomerular filtration rate in HIV-1-infected individuals treated with dolutegravir" @default.
• W2768868841 cites W1549276187 @default.
• W2768868841 cites W1970735835 @default.
• W2768868841 cites W1970994603 @default.
• W2768868841 cites W1983455184 @default.
• W2768868841 cites W1990925084 @default.
• W2768868841 cites W1995168686 @default.
• W2768868841 cites W1996083965 @default.
• W2768868841 cites W2002328695 @default.
• W2768868841 cites W2004880409 @default.
• W2768868841 cites W2010520337 @default.
• W2768868841 cites W2015795623 @default.
• W2768868841 cites W2017404902 @default.
• W2768868841 cites W2030599394 @default.
• W2768868841 cites W2034122697 @default.
• W2768868841 cites W2042272211 @default.
• W2768868841 cites W2045498828 @default.
• W2768868841 cites W2049229322 @default.
• W2768868841 cites W2052980167 @default.
• W2768868841 cites W2069997428 @default.
• W2768868841 cites W2073742622 @default.
• W2768868841 cites W2080493558 @default.
• W2768868841 cites W2080577693 @default.
• W2768868841 cites W2092934177 @default.
• W2768868841 cites W2093971642 @default.
• W2768868841 cites W2094160341 @default.
• W2768868841 cites W2096721822 @default.
• W2768868841 cites W2106095665 @default.
• W2768868841 cites W2113525844 @default.
• W2768868841 cites W2118625269 @default.
• W2768868841 cites W2121960517 @default.
• W2768868841 cites W2127680586 @default.
• W2768868841 cites W2137947649 @default.
• W2768868841 cites W2139430929 @default.
• W2768868841 cites W2152189242 @default.
• W2768868841 cites W2155792409 @default.
• W2768868841 cites W2155965977 @default.
• W2768868841 cites W2160308268 @default.
• W2768868841 cites W2397078747 @default.
• W2768868841 cites W2467247336 @default.
• W2768868841 cites W2583862987 @default.
• W2768868841 cites W2917732217 @default.
• W2768868841 cites W4241151929 @default.
• W2768868841 cites W566348055 @default.
• W2768868841 cites W1985577205 @default.
• W2768868841 doi "https://doi.org/10.1016/j.jiac.2017.10.015" @default.
• W2768868841 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29150412" @default.
• W2768868841 hasPublicationYear "2018" @default.
• W2768868841 type Work @default.
• W2768868841 sameAs 2768868841 @default.
• W2768868841 citedByCount "13" @default.
• W2768868841 countsByYear W27688688412018 @default.
• W2768868841 countsByYear W27688688412019 @default.
• W2768868841 countsByYear W27688688412020 @default.
• W2768868841 countsByYear W27688688412021 @default.
• W2768868841 countsByYear W27688688412022 @default.
• W2768868841 countsByYear W27688688412023 @default.
• W2768868841 crossrefType "journal-article" @default.
• W2768868841 hasAuthorship W2768868841A5014351560 @default.
• W2768868841 hasAuthorship W2768868841A5045763682 @default.
• W2768868841 hasAuthorship W2768868841A5051167036 @default.
• W2768868841 hasAuthorship W2768868841A5057822621 @default.
• W2768868841 hasBestOaLocation W27688688411 @default.
• W2768868841 hasConcept C126322002 @default.
• W2768868841 hasConcept C126894567 @default.
• W2768868841 hasConcept C138944611 @default.
• W2768868841 hasConcept C142462285 @default.
• W2768868841 hasConcept C159047783 @default.
• W2768868841 hasConcept C159641895 @default.
• W2768868841 hasConcept C185592680 @default.
• W2768868841 hasConcept C2776185481 @default.
• W2768868841 hasConcept C2779502633 @default.
• W2768868841 hasConcept C2779548226 @default.
• W2768868841 hasConcept C2779742124 @default.
• W2768868841 hasConcept C2780306776 @default.
• W2768868841 hasConcept C2993143319 @default.
• W2768868841 hasConcept C3013748606 @default.
• W2768868841 hasConcept C55493867 @default.
• W2768868841 hasConcept C71924100 @default.
• W2768868841 hasConceptScore W2768868841C126322002 @default.
• W2768868841 hasConceptScore W2768868841C126894567 @default.
• W2768868841 hasConceptScore W2768868841C138944611 @default.
• W2768868841 hasConceptScore W2768868841C142462285 @default.
• W2768868841 hasConceptScore W2768868841C159047783 @default.
• W2768868841 hasConceptScore W2768868841C159641895 @default.
• W2768868841 hasConceptScore W2768868841C185592680 @default.
• W2768868841 hasConceptScore W2768868841C2776185481 @default.
• W2768868841 hasConceptScore W2768868841C2779502633 @default.
• W2768868841 hasConceptScore W2768868841C2779548226 @default.
• W2768868841 hasConceptScore W2768868841C2779742124 @default.

• next