FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2769043953> ?p ?o ?g. }

• W2769043953 abstract "Abstract Glioblastoma stem-like cells (GSC) are hypothesized to evade current therapies and cause tumor recurrence, contributing to poor patient survival. Existing cell surface markers for GSC are developed from embryonic or neural stem cell systems; however, currently available GSC markers are suboptimal in sensitivity and specificity. We hypothesized that the GSC cell surface proteome could be mined with a yeast display antibody library to reveal novel immunophenotypes. We isolated an extensive collection of antibodies that were differentially selective for GSC. A single domain antibody VH-9.7 showed selectivity for five distinct patient-derived GSC lines and visualized orthotopic GBM xenografts in vivo after conjugation with a near-infrared dye. These findings demonstrate a previously unexplored high-throughput strategy for GSC-selective antibody discovery, to aid in GSC isolation, diagnostic imaging, and therapeutic targeting." @default.
• W2769043953 created "2017-12-04" @default.
• W2769043953 creator A5016216963 @default.
• W2769043953 creator A5017967519 @default.
• W2769043953 creator A5025343176 @default.
• W2769043953 creator A5051851997 @default.
• W2769043953 creator A5054371127 @default.
• W2769043953 creator A5081858756 @default.
• W2769043953 date "2017-11-20" @default.
• W2769043953 modified "2023-09-26" @default.
• W2769043953 title "Yeast display biopanning identifies human antibodies targeting glioblastoma stem-like cells" @default.
• W2769043953 cites W107883495 @default.
• W2769043953 cites W1254161066 @default.
• W2769043953 cites W1498780407 @default.
• W2769043953 cites W1564078780 @default.
• W2769043953 cites W1584021532 @default.
• W2769043953 cites W1912794777 @default.
• W2769043953 cites W1971498704 @default.
• W2769043953 cites W1972700706 @default.
• W2769043953 cites W1977252540 @default.
• W2769043953 cites W1981394138 @default.
• W2769043953 cites W1982177800 @default.
• W2769043953 cites W1983644260 @default.
• W2769043953 cites W1988986134 @default.
• W2769043953 cites W1989848808 @default.
• W2769043953 cites W1995801067 @default.
• W2769043953 cites W1997333460 @default.
• W2769043953 cites W1998450685 @default.
• W2769043953 cites W2001544973 @default.
• W2769043953 cites W2005008347 @default.
• W2769043953 cites W2018671779 @default.
• W2769043953 cites W2034083624 @default.
• W2769043953 cites W2034207334 @default.
• W2769043953 cites W2042384460 @default.
• W2769043953 cites W2055340768 @default.
• W2769043953 cites W2055948888 @default.
• W2769043953 cites W2056600802 @default.
• W2769043953 cites W2060551076 @default.
• W2769043953 cites W2072183005 @default.
• W2769043953 cites W2076775906 @default.
• W2769043953 cites W2081758137 @default.
• W2769043953 cites W2087257698 @default.
• W2769043953 cites W2090350928 @default.
• W2769043953 cites W2091149944 @default.
• W2769043953 cites W2096287682 @default.
• W2769043953 cites W2100928421 @default.
• W2769043953 cites W2109844644 @default.
• W2769043953 cites W2113070980 @default.
• W2769043953 cites W2117058176 @default.
• W2769043953 cites W2120878638 @default.
• W2769043953 cites W2124078079 @default.
• W2769043953 cites W2126799977 @default.
• W2769043953 cites W2129944198 @default.
• W2769043953 cites W2134967813 @default.
• W2769043953 cites W2139403793 @default.
• W2769043953 cites W2142815489 @default.
• W2769043953 cites W2153165671 @default.
• W2769043953 cites W2153478981 @default.
• W2769043953 cites W2157907127 @default.
• W2769043953 cites W2167414381 @default.
• W2769043953 cites W2167650288 @default.
• W2769043953 cites W2205491921 @default.
• W2769043953 cites W2225524101 @default.
• W2769043953 cites W2268290622 @default.
• W2769043953 cites W2314371091 @default.
• W2769043953 cites W2332242335 @default.
• W2769043953 cites W2406772379 @default.
• W2769043953 cites W2461032442 @default.
• W2769043953 cites W2472318494 @default.
• W2769043953 cites W2513748822 @default.
• W2769043953 cites W2520274186 @default.
• W2769043953 cites W2520760482 @default.
• W2769043953 doi "https://doi.org/10.1038/s41598-017-16066-1" @default.
• W2769043953 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5696472" @default.
• W2769043953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29158489" @default.
• W2769043953 hasPublicationYear "2017" @default.
• W2769043953 type Work @default.
• W2769043953 sameAs 2769043953 @default.
• W2769043953 citedByCount "18" @default.
• W2769043953 countsByYear W27690439532018 @default.
• W2769043953 countsByYear W27690439532019 @default.
• W2769043953 countsByYear W27690439532020 @default.
• W2769043953 countsByYear W27690439532021 @default.
• W2769043953 countsByYear W27690439532022 @default.
• W2769043953 countsByYear W27690439532023 @default.
• W2769043953 crossrefType "journal-article" @default.
• W2769043953 hasAuthorship W2769043953A5016216963 @default.
• W2769043953 hasAuthorship W2769043953A5017967519 @default.
• W2769043953 hasAuthorship W2769043953A5025343176 @default.
• W2769043953 hasAuthorship W2769043953A5051851997 @default.
• W2769043953 hasAuthorship W2769043953A5054371127 @default.
• W2769043953 hasAuthorship W2769043953A5081858756 @default.
• W2769043953 hasBestOaLocation W27690439531 @default.
• W2769043953 hasConcept C104317684 @default.
• W2769043953 hasConcept C104428545 @default.
• W2769043953 hasConcept C136834591 @default.
• W2769043953 hasConcept C145103041 @default.
• W2769043953 hasConcept C1491633281 @default.
• W2769043953 hasConcept C159654299 @default.
• W2769043953 hasConcept C167625842 @default.

• next