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- W2769064009 abstract "Alphaviruses are important human pathogens that cause diseases ranging from acute and chronic polyarthralgia to encephalitis. Transmitted by mosquito vectors, alphaviruses have high potential for emergence and have initiated several recent epidemics. The innate immune response is critical for controlling the acute phase of alphavirus disease, and the induction of type I interferon (IFN) is essential in this response. In this review, we discuss our current understanding of innate host sensors that initiate antiviral responses following alphavirus infection, and the IFN-induced effector proteins that limit alphavirus replication and dissemination." @default.
- W2769064009 created "2017-12-04" @default.
- W2769064009 creator A5047702020 @default.
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- W2769064009 date "2018-02-01" @default.
- W2769064009 modified "2023-10-12" @default.
- W2769064009 title "Innate immune control of alphavirus infection" @default.
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- W2769064009 doi "https://doi.org/10.1016/j.coviro.2017.11.006" @default.
- W2769064009 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5835171" @default.
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