Matches in SemOpenAlex for { <https://semopenalex.org/work/W2769155929> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2769155929 endingPage "154" @default.
- W2769155929 startingPage "154" @default.
- W2769155929 abstract "Introduction: The pathogenesis of alopecia areata (AA) remains incompletely understood. Different cytokines may play a role in AA. Tumor necrosis factor-alpha (TNF-α) has been shown to be inhibitory to hair follicle growth in in vitro studies suggesting that it may play an important role in AA. This study was conducted to assess the presence of TNF-α in lesional and nonlesional skin of AA, to review its possible role in AA, and to show whether AA is a systemic or localized disease by comparing the level of TNF-α between lesional and nonlesional skin biopsies of the patients. Materials and Methods: Thirty patients with AA and thirty age- and sex-matched healthy controls were included in the study. A 4 mm punch skin biopsy was taken from lesional and nonlesional skin of every patient, as well as from the normal skin of each individual in the control group for immunohistochemical analysis of TNF-α. Results: The level of TNF-α in lesional skin biopsies was significantly higher than in nonlesional skin biopsies of patients as well as controls' biopsies. Furthermore, TNF-α level in nonlesional biopsies of patients was significantly higher than the level in controls' biopsies. Conclusions: We concluded that skin of AA has a high level of TNF-α (a normal inhibitor of hair follicle growth in vitro). This high level may point to the important role of TNF-α in AA. Further studies should be conducted to detect the level of TNF-α in long-standing AA and the more severe cases of AA." @default.
- W2769155929 created "2017-12-04" @default.
- W2769155929 creator A5044412121 @default.
- W2769155929 creator A5079460912 @default.
- W2769155929 date "2017-01-01" @default.
- W2769155929 modified "2023-09-27" @default.
- W2769155929 title "Detection of tumor necrosis factor-alpha in nonlesional tissues of alopecia areata patients: A prove for a systemic disease" @default.
- W2769155929 cites W1537167162 @default.
- W2769155929 cites W1968216911 @default.
- W2769155929 cites W1971220784 @default.
- W2769155929 cites W1973789107 @default.
- W2769155929 cites W1985141915 @default.
- W2769155929 cites W1986786571 @default.
- W2769155929 cites W2015733931 @default.
- W2769155929 cites W2017483812 @default.
- W2769155929 cites W2058233090 @default.
- W2769155929 cites W2078226624 @default.
- W2769155929 cites W2079276592 @default.
- W2769155929 cites W2089231559 @default.
- W2769155929 cites W2133348899 @default.
- W2769155929 cites W2156337104 @default.
- W2769155929 cites W2339287040 @default.
- W2769155929 cites W2412175141 @default.
- W2769155929 cites W2414662891 @default.
- W2769155929 doi "https://doi.org/10.4103/ijt.ijt_47_17" @default.
- W2769155929 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5655623" @default.
- W2769155929 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29118519" @default.
- W2769155929 hasPublicationYear "2017" @default.
- W2769155929 type Work @default.
- W2769155929 sameAs 2769155929 @default.
- W2769155929 citedByCount "7" @default.
- W2769155929 countsByYear W27691559292018 @default.
- W2769155929 countsByYear W27691559292020 @default.
- W2769155929 countsByYear W27691559292021 @default.
- W2769155929 countsByYear W27691559292022 @default.
- W2769155929 countsByYear W27691559292023 @default.
- W2769155929 crossrefType "journal-article" @default.
- W2769155929 hasAuthorship W2769155929A5044412121 @default.
- W2769155929 hasAuthorship W2769155929A5079460912 @default.
- W2769155929 hasBestOaLocation W27691559292 @default.
- W2769155929 hasConcept C126322002 @default.
- W2769155929 hasConcept C142724271 @default.
- W2769155929 hasConcept C17991360 @default.
- W2769155929 hasConcept C203014093 @default.
- W2769155929 hasConcept C204232928 @default.
- W2769155929 hasConcept C2775934546 @default.
- W2769155929 hasConcept C2777216303 @default.
- W2769155929 hasConcept C2777524370 @default.
- W2769155929 hasConcept C2778674544 @default.
- W2769155929 hasConcept C2779134260 @default.
- W2769155929 hasConcept C2780439664 @default.
- W2769155929 hasConcept C2780942790 @default.
- W2769155929 hasConcept C503630168 @default.
- W2769155929 hasConcept C71924100 @default.
- W2769155929 hasConcept C90924648 @default.
- W2769155929 hasConceptScore W2769155929C126322002 @default.
- W2769155929 hasConceptScore W2769155929C142724271 @default.
- W2769155929 hasConceptScore W2769155929C17991360 @default.
- W2769155929 hasConceptScore W2769155929C203014093 @default.
- W2769155929 hasConceptScore W2769155929C204232928 @default.
- W2769155929 hasConceptScore W2769155929C2775934546 @default.
- W2769155929 hasConceptScore W2769155929C2777216303 @default.
- W2769155929 hasConceptScore W2769155929C2777524370 @default.
- W2769155929 hasConceptScore W2769155929C2778674544 @default.
- W2769155929 hasConceptScore W2769155929C2779134260 @default.
- W2769155929 hasConceptScore W2769155929C2780439664 @default.
- W2769155929 hasConceptScore W2769155929C2780942790 @default.
- W2769155929 hasConceptScore W2769155929C503630168 @default.
- W2769155929 hasConceptScore W2769155929C71924100 @default.
- W2769155929 hasConceptScore W2769155929C90924648 @default.
- W2769155929 hasIssue "4" @default.
- W2769155929 hasLocation W27691559291 @default.
- W2769155929 hasLocation W27691559292 @default.
- W2769155929 hasLocation W27691559293 @default.
- W2769155929 hasLocation W27691559294 @default.
- W2769155929 hasOpenAccess W2769155929 @default.
- W2769155929 hasPrimaryLocation W27691559291 @default.
- W2769155929 hasRelatedWork W1979859878 @default.
- W2769155929 hasRelatedWork W2380167026 @default.
- W2769155929 hasRelatedWork W2402339253 @default.
- W2769155929 hasRelatedWork W2415133252 @default.
- W2769155929 hasRelatedWork W2469038553 @default.
- W2769155929 hasRelatedWork W2745102150 @default.
- W2769155929 hasRelatedWork W2769155929 @default.
- W2769155929 hasRelatedWork W2799671781 @default.
- W2769155929 hasRelatedWork W2953931984 @default.
- W2769155929 hasRelatedWork W4200066940 @default.
- W2769155929 hasVolume "9" @default.
- W2769155929 isParatext "false" @default.
- W2769155929 isRetracted "false" @default.
- W2769155929 magId "2769155929" @default.
- W2769155929 workType "article" @default.