FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2769494938> ?p ?o ?g. }

• W2769494938 endingPage "40" @default.
• W2769494938 startingPage "33" @default.
• W2769494938 abstract "[ <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>18</sup> F] fluorothymidine ( <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>18</sup> F-FLT) positron emission tomography (PET) can be used for quantifying tumor proliferation and its changes during chemoradiotherapy (CRT) in head and neck squamous cell carcinoma (HNSCC). We investigated the complementary prognostic value of sphericity (one of several available 3-D shape descriptors) and standard metrics in <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>18</sup> F-FLT PET images before and during CRT regarding 4-year disease-free survival (DFS). Forty-eight HNSCC patients treated with CRT underwent <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>18</sup> F-FLT PET/CT before and during CRT. Median follow-up was 52 months. Primary tumors were automatically delineated and characterized by extracting max and mean standardized uptake value (SUV), proliferative volume and associated sphericity. Prognostic value for DFS of clinical and imaging features was assessed using Kaplan-Meier survival analysis. In univariate analysis after correction for multiple testing, the per-treatment sphericity (HR = 4.2, p = 0.02) and SUVmean (HR = 4.1, p = 0.03) were prognostic factors, whereas none of the pretreatment variables were significant. Reduction in SUVmax (HR = 4, p = 0.04) was also a prognostic factor, but not reduction of proliferative tumor volume. The best stratification of patients for DFS was achieved by combining per-treatment SUVmean and sphericity (HR = 6.7, p <; 0.001). High sphericity combined with low mean <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>18</sup> F-FLT uptake during treatment were associated with better DFS. These results suggest the potential prognostic value of tumor characterization from <sup xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>18</sup> F-FLT PET in HNSCC that may be further explored in larger cohorts." @default.
• W2769494938 created "2017-12-04" @default.
• W2769494938 creator A5000396669 @default.
• W2769494938 creator A5017138072 @default.
• W2769494938 creator A5032314957 @default.
• W2769494938 creator A5044303463 @default.
• W2769494938 creator A5069087161 @default.
• W2769494938 creator A5081133601 @default.
• W2769494938 creator A5084044092 @default.
• W2769494938 creator A5084710251 @default.
• W2769494938 creator A5090088826 @default.
• W2769494938 date "2018-01-01" @default.
• W2769494938 modified "2023-09-27" @default.
• W2769494938 title "Prognostic Value of Head and Neck Tumor Proliferative Sphericity From 3’-Deoxy-3’-[¹⁸F] Fluorothymidine Positron Emission Tomography" @default.
• W2769494938 cites W1892105223 @default.
• W2769494938 cites W1966437930 @default.
• W2769494938 cites W1977127004 @default.
• W2769494938 cites W1987934775 @default.
• W2769494938 cites W2009669046 @default.
• W2769494938 cites W2021605236 @default.
• W2769494938 cites W2022587304 @default.
• W2769494938 cites W2034225567 @default.
• W2769494938 cites W2036902954 @default.
• W2769494938 cites W2043453187 @default.
• W2769494938 cites W2074445922 @default.
• W2769494938 cites W2084919861 @default.
• W2769494938 cites W2089588713 @default.
• W2769494938 cites W2091777454 @default.
• W2769494938 cites W2103548575 @default.
• W2769494938 cites W2103780528 @default.
• W2769494938 cites W2110593170 @default.
• W2769494938 cites W2110664940 @default.
• W2769494938 cites W2114710446 @default.
• W2769494938 cites W2120046399 @default.
• W2769494938 cites W2128739912 @default.
• W2769494938 cites W2130147370 @default.
• W2769494938 cites W2151415400 @default.
• W2769494938 cites W2152089420 @default.
• W2769494938 cites W2152575748 @default.
• W2769494938 cites W2155263737 @default.
• W2769494938 cites W2155384808 @default.
• W2769494938 cites W2156578106 @default.
• W2769494938 cites W2156835537 @default.
• W2769494938 cites W2163154863 @default.
• W2769494938 cites W2409456704 @default.
• W2769494938 cites W2473669542 @default.
• W2769494938 cites W2499202527 @default.
• W2769494938 cites W2528857716 @default.
• W2769494938 cites W2770348255 @default.
• W2769494938 cites W4233857083 @default.
• W2769494938 doi "https://doi.org/10.1109/trpms.2017.2777890" @default.
• W2769494938 hasPublicationYear "2018" @default.
• W2769494938 type Work @default.
• W2769494938 sameAs 2769494938 @default.
• W2769494938 citedByCount "12" @default.
• W2769494938 countsByYear W27694949382018 @default.
• W2769494938 countsByYear W27694949382019 @default.
• W2769494938 countsByYear W27694949382020 @default.
• W2769494938 countsByYear W27694949382021 @default.
• W2769494938 countsByYear W27694949382022 @default.
• W2769494938 countsByYear W27694949382023 @default.
• W2769494938 crossrefType "journal-article" @default.
• W2769494938 hasAuthorship W2769494938A5000396669 @default.
• W2769494938 hasAuthorship W2769494938A5017138072 @default.
• W2769494938 hasAuthorship W2769494938A5032314957 @default.
• W2769494938 hasAuthorship W2769494938A5044303463 @default.
• W2769494938 hasAuthorship W2769494938A5069087161 @default.
• W2769494938 hasAuthorship W2769494938A5081133601 @default.
• W2769494938 hasAuthorship W2769494938A5084044092 @default.
• W2769494938 hasAuthorship W2769494938A5084710251 @default.
• W2769494938 hasAuthorship W2769494938A5090088826 @default.
• W2769494938 hasConcept C126322002 @default.
• W2769494938 hasConcept C143998085 @default.
• W2769494938 hasConcept C173913448 @default.
• W2769494938 hasConcept C199374082 @default.
• W2769494938 hasConcept C2524010 @default.
• W2769494938 hasConcept C2775842073 @default.
• W2769494938 hasConcept C2776530083 @default.
• W2769494938 hasConcept C2776833033 @default.
• W2769494938 hasConcept C2778424827 @default.
• W2769494938 hasConcept C2989005 @default.
• W2769494938 hasConcept C3019894029 @default.
• W2769494938 hasConcept C33923547 @default.
• W2769494938 hasConcept C509974204 @default.
• W2769494938 hasConcept C71924100 @default.
• W2769494938 hasConceptScore W2769494938C126322002 @default.
• W2769494938 hasConceptScore W2769494938C143998085 @default.
• W2769494938 hasConceptScore W2769494938C173913448 @default.
• W2769494938 hasConceptScore W2769494938C199374082 @default.
• W2769494938 hasConceptScore W2769494938C2524010 @default.
• W2769494938 hasConceptScore W2769494938C2775842073 @default.
• W2769494938 hasConceptScore W2769494938C2776530083 @default.
• W2769494938 hasConceptScore W2769494938C2776833033 @default.
• W2769494938 hasConceptScore W2769494938C2778424827 @default.
• W2769494938 hasConceptScore W2769494938C2989005 @default.
• W2769494938 hasConceptScore W2769494938C3019894029 @default.
• W2769494938 hasConceptScore W2769494938C33923547 @default.
• W2769494938 hasConceptScore W2769494938C509974204 @default.

• next