FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2769673364> ?p ?o ?g. }

• W2769673364 endingPage "108999" @default.
• W2769673364 startingPage "108989" @default.
• W2769673364 abstract "// Chih-Wei Chen 1, 2, 3 , Tain-Junn Cheng 3, 4 , Chung-Han Ho 5, 6 , Jhi-Joung Wang 5, 7 , Shih-Feng Weng 5, 8 , Ya-Chin Hou 1 , Hung-Chi Cheng 9 , Chung-Ching Chio 2 , Yan-Shen Shan 1, 10 and Wen-Tsan Chang 1, 9 1 Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan 2 Division of Neurosurgery, Department of Surgery, Chi Mei Foundation Medical Center, Tainan 710, Taiwan 3 Department of Occupational Safety and Health/Institute of Industrial Safety and Disaster Prevention, College of Sustainable Environment, Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan 4 Department of Neurology and Occupational Medicine, Chi Mei Foundation Medical Center, Tainan 710, Taiwan 5 Department of Medical Research, Chi Mei Foundation Medical Center, Tainan 710, Taiwan 6 Department of Hospital and Health Care Administration, Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan 7 Department of Anesthesiology, Chi Mei Foundation Medical Center, Tainan 710, Taiwan 8 Department of Health Care Administration and Medical Informatics, Kaohsiung Medical University, Kaohsiung 807, Taiwan 9 Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan 10 Division of General Surgery, Department of Surgery, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan Correspondence to: Wen-Tsan Chang, email: wtchang@mail.ncku.edu.tw Keywords: stroke; ischemic stroke; brain cancer; glioblastoma mutiforme (GBM); nationwide population-based cohort Received: July 20, 2017      Accepted: August 19, 2017      Published: November 15, 2017 ABSTRACT Stroke and brain cancer are two distinct diseases. However, the relationship between both diseases has rarely been examined. This study investigated the longitudinal risk for developing brain cancer in stroke patients. To study this, we first reviewed the malignant gliomas previously with or without stroke using brain magnetic resonance imaging (MRI) images and the past histories. Two ischemic stroke patients before the malignant glioma were identified and belonged to the glioblastoma mutiforme (GBM). Particularly, both GBM specimens displayed strong hypoxia-inducible factor 1α (HIF-1α) expression in immunohistochemical (IHC) staining. To elucidate the significance of this relationship, we then used a nationwide population-based cohort in Taiwan to investigate the risk for the incidence of brain cancer in patients previously with or without stroke. The incidence of all tumors in the stroke group was lower than that in the control group with an adjusted hazard ratio (HR) of 0.79 (95% confidence interval [CI]: 0.74-0.84) in both gender and age older than 60 years. But the stroke patients had higher risk of developing only brain cancer with an adjusted HR of 3.09 (95% CI: 1.80-5.30), and otherwise had lower risk of developing head and neck, digestive, respiratory, bone and skin, as well as other tumors, all with p<0.05. After stratification by gender and age, the female and aged 40-60 year old stroke patients had higher risk of developing brain cancer with an adjusted HR of 7.41 (95% CI: 3.30-16.64) and 16.34 (95% CI: 4.45-62.13), respectively, both with p<0.05. Patients with stroke, in particular female and age 40-60 years old, have an increased risk for developing brain cancer." @default.
• W2769673364 created "2017-12-04" @default.
• W2769673364 creator A5015953475 @default.
• W2769673364 creator A5016983003 @default.
• W2769673364 creator A5021567686 @default.
• W2769673364 creator A5025329742 @default.
• W2769673364 creator A5026099931 @default.
• W2769673364 creator A5038395378 @default.
• W2769673364 creator A5053244235 @default.
• W2769673364 creator A5083110030 @default.
• W2769673364 creator A5085611122 @default.
• W2769673364 creator A5090715275 @default.
• W2769673364 date "2017-11-15" @default.
• W2769673364 modified "2023-10-16" @default.
• W2769673364 title "Increased risk of brain cancer incidence in stroke patients: a clinical case series, population-based and longitudinal follow-up study" @default.
• W2769673364 cites W1870761595 @default.
• W2769673364 cites W1938578931 @default.
• W2769673364 cites W1968686048 @default.
• W2769673364 cites W1973418697 @default.
• W2769673364 cites W1980429797 @default.
• W2769673364 cites W1987904413 @default.
• W2769673364 cites W1989570486 @default.
• W2769673364 cites W1996810856 @default.
• W2769673364 cites W1997743917 @default.
• W2769673364 cites W2014344662 @default.
• W2769673364 cites W2015344488 @default.
• W2769673364 cites W2017613300 @default.
• W2769673364 cites W2018093166 @default.
• W2769673364 cites W2024487695 @default.
• W2769673364 cites W2025353314 @default.
• W2769673364 cites W2032446655 @default.
• W2769673364 cites W2043675663 @default.
• W2769673364 cites W2047585900 @default.
• W2769673364 cites W2048995205 @default.
• W2769673364 cites W2070412580 @default.
• W2769673364 cites W2071674957 @default.
• W2769673364 cites W2071881656 @default.
• W2769673364 cites W2073847006 @default.
• W2769673364 cites W2075396670 @default.
• W2769673364 cites W2079365338 @default.
• W2769673364 cites W2087422584 @default.
• W2769673364 cites W2087846775 @default.
• W2769673364 cites W2098972920 @default.
• W2769673364 cites W2099133299 @default.
• W2769673364 cites W2113996383 @default.
• W2769673364 cites W2119394719 @default.
• W2769673364 cites W2132697290 @default.
• W2769673364 cites W2134201967 @default.
• W2769673364 cites W2141351251 @default.
• W2769673364 cites W2148977460 @default.
• W2769673364 cites W2158794894 @default.
• W2769673364 cites W2161522110 @default.
• W2769673364 cites W2176412441 @default.
• W2769673364 cites W2618664020 @default.
• W2769673364 cites W2726392696 @default.
• W2769673364 cites W2917837889 @default.
• W2769673364 cites W4235653677 @default.
• W2769673364 cites W4242403727 @default.
• W2769673364 doi "https://doi.org/10.18632/oncotarget.22480" @default.
• W2769673364 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5752498" @default.
• W2769673364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29312585" @default.
• W2769673364 hasPublicationYear "2017" @default.
• W2769673364 type Work @default.
• W2769673364 sameAs 2769673364 @default.
• W2769673364 citedByCount "18" @default.
• W2769673364 countsByYear W27696733642019 @default.
• W2769673364 countsByYear W27696733642020 @default.
• W2769673364 countsByYear W27696733642021 @default.
• W2769673364 countsByYear W27696733642022 @default.
• W2769673364 countsByYear W27696733642023 @default.
• W2769673364 crossrefType "journal-article" @default.
• W2769673364 hasAuthorship W2769673364A5015953475 @default.
• W2769673364 hasAuthorship W2769673364A5016983003 @default.
• W2769673364 hasAuthorship W2769673364A5021567686 @default.
• W2769673364 hasAuthorship W2769673364A5025329742 @default.
• W2769673364 hasAuthorship W2769673364A5026099931 @default.
• W2769673364 hasAuthorship W2769673364A5038395378 @default.
• W2769673364 hasAuthorship W2769673364A5053244235 @default.
• W2769673364 hasAuthorship W2769673364A5083110030 @default.
• W2769673364 hasAuthorship W2769673364A5085611122 @default.
• W2769673364 hasAuthorship W2769673364A5090715275 @default.
• W2769673364 hasBestOaLocation W27696733641 @default.
• W2769673364 hasConcept C104863432 @default.
• W2769673364 hasConcept C2908647359 @default.
• W2769673364 hasConcept C3018419874 @default.
• W2769673364 hasConcept C509550671 @default.
• W2769673364 hasConcept C512399662 @default.
• W2769673364 hasConcept C71924100 @default.
• W2769673364 hasConcept C99454951 @default.
• W2769673364 hasConceptScore W2769673364C104863432 @default.
• W2769673364 hasConceptScore W2769673364C2908647359 @default.
• W2769673364 hasConceptScore W2769673364C3018419874 @default.
• W2769673364 hasConceptScore W2769673364C509550671 @default.
• W2769673364 hasConceptScore W2769673364C512399662 @default.
• W2769673364 hasConceptScore W2769673364C71924100 @default.
• W2769673364 hasConceptScore W2769673364C99454951 @default.
• W2769673364 hasIssue "65" @default.
• W2769673364 hasLocation W27696733641 @default.

• next