FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2769722377> ?p ?o ?g. }

• W2769722377 endingPage "114" @default.
• W2769722377 startingPage "108" @default.
• W2769722377 abstract "Ovalbumin (OVA), a major allergen from hen's egg albumen, tends to aggregate when heated. Depending on the balance of attractive and repulsive interactions, heat-induced OVA aggregates have various morphologies, which differ in digestibility. In the context of food allergy to egg, we investigated the ability of native and thermally aggregated OVA as well as their digests to induce the degranulation of a humanized rat basophil leukemia (RBL) cell line, which was sensitized with a pool of sera from egg-allergic children. Native and two thermally aggregated OVA forms were digested in vitro using a gastrointestinal digestion model based on the INFOGEST harmonized protocol including a final degradation with jejunal brush border membranes (BBM) enzymes. The course of digestion was monitored by the OPA method and by RP-HPLC. Digestibility was OVA small aggregates > OVA large aggregates >> native OVA and BBM peptidases only significantly hydrolyzed small-sized peptides from gastro-duodenal digests of the aggregates. The degranulation ability of the native OVA slightly changed during the gastric phase but mostly decreased during the duodenal digestion with no further change with BBM digestion. The degranulation ability of aggregates, which was significantly lower than the ability of native OVA, was not significantly affected by digestion. Digestibility and ability to induce basophil degranulation can thus not be straightforward linked." @default.
• W2769722377 created "2017-12-04" @default.
• W2769722377 creator A5007711668 @default.
• W2769722377 creator A5023105092 @default.
• W2769722377 creator A5059593451 @default.
• W2769722377 creator A5086699828 @default.
• W2769722377 creator A5087048224 @default.
• W2769722377 creator A5087999081 @default.
• W2769722377 creator A5091752013 @default.
• W2769722377 date "2019-04-01" @default.
• W2769722377 modified "2023-10-18" @default.
• W2769722377 title "Digestion differently affects the ability of native and thermally aggregated ovalbumin to trigger basophil activation" @default.
• W2769722377 cites W1531267945 @default.
• W2769722377 cites W1875031733 @default.
• W2769722377 cites W193395044 @default.
• W2769722377 cites W1968392300 @default.
• W2769722377 cites W1982650540 @default.
• W2769722377 cites W1986518331 @default.
• W2769722377 cites W2001852030 @default.
• W2769722377 cites W2006204681 @default.
• W2769722377 cites W2013467987 @default.
• W2769722377 cites W2013528808 @default.
• W2769722377 cites W2023850381 @default.
• W2769722377 cites W2045198469 @default.
• W2769722377 cites W2046113844 @default.
• W2769722377 cites W2063123250 @default.
• W2769722377 cites W2133009926 @default.
• W2769722377 cites W2134876089 @default.
• W2769722377 cites W2145746728 @default.
• W2769722377 cites W2147172644 @default.
• W2769722377 cites W2149462204 @default.
• W2769722377 cites W2156565455 @default.
• W2769722377 cites W2160446463 @default.
• W2769722377 cites W2169261819 @default.
• W2769722377 cites W2264380864 @default.
• W2769722377 cites W2608697170 @default.
• W2769722377 cites W4239393922 @default.
• W2769722377 cites W4251260245 @default.
• W2769722377 doi "https://doi.org/10.1016/j.foodres.2017.11.040" @default.
• W2769722377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30898346" @default.
• W2769722377 hasPublicationYear "2019" @default.
• W2769722377 type Work @default.
• W2769722377 sameAs 2769722377 @default.
• W2769722377 citedByCount "14" @default.
• W2769722377 countsByYear W27697223772019 @default.
• W2769722377 countsByYear W27697223772020 @default.
• W2769722377 countsByYear W27697223772021 @default.
• W2769722377 countsByYear W27697223772022 @default.
• W2769722377 countsByYear W27697223772023 @default.
• W2769722377 crossrefType "journal-article" @default.
• W2769722377 hasAuthorship W2769722377A5007711668 @default.
• W2769722377 hasAuthorship W2769722377A5023105092 @default.
• W2769722377 hasAuthorship W2769722377A5059593451 @default.
• W2769722377 hasAuthorship W2769722377A5086699828 @default.
• W2769722377 hasAuthorship W2769722377A5087048224 @default.
• W2769722377 hasAuthorship W2769722377A5087999081 @default.
• W2769722377 hasAuthorship W2769722377A5091752013 @default.
• W2769722377 hasBestOaLocation W27697223771 @default.
• W2769722377 hasConcept C130316041 @default.
• W2769722377 hasConcept C141105273 @default.
• W2769722377 hasConcept C159654299 @default.
• W2769722377 hasConcept C170493617 @default.
• W2769722377 hasConcept C185592680 @default.
• W2769722377 hasConcept C203014093 @default.
• W2769722377 hasConcept C2776946954 @default.
• W2769722377 hasConcept C2777456892 @default.
• W2769722377 hasConcept C2781357212 @default.
• W2769722377 hasConcept C41625074 @default.
• W2769722377 hasConcept C43617362 @default.
• W2769722377 hasConcept C49802076 @default.
• W2769722377 hasConcept C5426402 @default.
• W2769722377 hasConcept C55493867 @default.
• W2769722377 hasConcept C86803240 @default.
• W2769722377 hasConcept C8891405 @default.
• W2769722377 hasConceptScore W2769722377C130316041 @default.
• W2769722377 hasConceptScore W2769722377C141105273 @default.
• W2769722377 hasConceptScore W2769722377C159654299 @default.
• W2769722377 hasConceptScore W2769722377C170493617 @default.
• W2769722377 hasConceptScore W2769722377C185592680 @default.
• W2769722377 hasConceptScore W2769722377C203014093 @default.
• W2769722377 hasConceptScore W2769722377C2776946954 @default.
• W2769722377 hasConceptScore W2769722377C2777456892 @default.
• W2769722377 hasConceptScore W2769722377C2781357212 @default.
• W2769722377 hasConceptScore W2769722377C41625074 @default.
• W2769722377 hasConceptScore W2769722377C43617362 @default.
• W2769722377 hasConceptScore W2769722377C49802076 @default.
• W2769722377 hasConceptScore W2769722377C5426402 @default.
• W2769722377 hasConceptScore W2769722377C55493867 @default.
• W2769722377 hasConceptScore W2769722377C86803240 @default.
• W2769722377 hasConceptScore W2769722377C8891405 @default.
• W2769722377 hasFunder F4320322727 @default.
• W2769722377 hasFunder F4320323910 @default.
• W2769722377 hasLocation W27697223771 @default.
• W2769722377 hasLocation W27697223772 @default.
• W2769722377 hasLocation W27697223773 @default.
• W2769722377 hasLocation W27697223774 @default.
• W2769722377 hasOpenAccess W2769722377 @default.
• W2769722377 hasPrimaryLocation W27697223771 @default.

• next