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• W2769735050 abstract "Self-assembly of short de novo designed peptides gives rise to catalytic amyloids capable of facilitating multiple chemical transformations. We show that catalytic amyloids can efficiently hydrolyze paraoxon, a widely used, highly toxic organophosphate pesticide. Moreover, these robust and inexpensive metal-containing materials can be easily deposited on various surfaces producing catalytic flow devices. Finally, functional promiscuity of catalytic amyloids promotes tandem hydrolysis/oxidation reactions. High efficiency discovered in a very small library of peptides suggests an enormous potential for further improvement of catalytic properties both in terms of catalytic efficiency and substrate scope." @default.
• W2769735050 created "2017-12-04" @default.
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• W2769735050 date "2017-11-28" @default.
• W2769735050 modified "2023-10-17" @default.
• W2769735050 title "Copper-Containing Catalytic Amyloids Promote Phosphoester Hydrolysis and Tandem Reactions" @default.
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• W2769735050 doi "https://doi.org/10.1021/acscatal.7b03323" @default.
• W2769735050 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6181230" @default.
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