FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2769832823> ?p ?o ?g. }

• W2769832823 abstract "Introduction The benefits of lung protective ventilation have been replicated in multiple trials. 1,2 However, we suspected that adherence to this standard of care remained poor. Using the NIHR critical care Health Informatics Collaborative (ccHIC) database, we analysed data from 11 teaching hospital intensive care units (22 524 patient episodes) to investigate real-world clinical practice. Methods 1248 patient episodes, where ventilation was continued for ≥48 hours, with 232,600 hours of concurrent mechanical ventilation and blood gas data were identified as suitable for analysis. Short gaps in ventilation ( Results The median tidal volume received by patients was 7.3 ml/kg -1 PBW (IQR:5.7–8.8). Female patients, especially those with higher BMI (≥30 kgm -2 ) consistently received higher tidal volumes than males. Patients with severe respiratory failure (PaO 2 :FiO 2 -1 PBW, and had 71% ICU mortality (Table 1). Patients with respiratory failure sufficient to qualify for recruitment into recent clinical trials (PaO 2 :FiO 2 2 0), who were exposed to tidal volumes≥12 ml/kg -1 PBW for longer than two hours had significantly increased risk of ICU mortality (odds ratio=2.89 [1.25–7.2]; p=0.007); This was not observed for patients with PaO 2 :FiO 2 ≥40 kPa (odds ratio=0.95 [0.58–1.56], p=0.91). Conclusions More than 15 years after the ARMA study 1 demonstrated a mortality benefit from lung protective ventilation, we are still not implementing 6 ml/kg -1 PBW ventilation into clinical practice, and are exposing even patients with a severe respiratory failure (PaO 2 :FiO 2 2 :FiO 2 2 :FiO 2 ≥40 kPa. References ARDS Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for ALI and ARDS. NEJM 2000;342:1301–1308. Futier E et al . A trial of intraoperative low tidal volume ventilation in abdominal surgery. NEJM 2013;369:428–437." @default.
• W2769832823 created "2017-12-04" @default.
• W2769832823 creator A5008607732 @default.
• W2769832823 creator A5013117957 @default.
• W2769832823 creator A5018938467 @default.
• W2769832823 creator A5022826906 @default.
• W2769832823 creator A5032741507 @default.
• W2769832823 creator A5034919407 @default.
• W2769832823 creator A5046005276 @default.
• W2769832823 creator A5046351592 @default.
• W2769832823 creator A5048777602 @default.
• W2769832823 creator A5051552019 @default.
• W2769832823 creator A5060830413 @default.
• W2769832823 creator A5062276392 @default.
• W2769832823 creator A5067694107 @default.
• W2769832823 creator A5082629342 @default.
• W2769832823 date "2017-11-15" @default.
• W2769832823 modified "2023-09-26" @default.
• W2769832823 title "S136 Lung protective mechanical ventilation for acute respiratory failure is not being implemented in uk clinical practice" @default.
• W2769832823 doi "https://doi.org/10.1136/thoraxjnl-2017-210983.142" @default.
• W2769832823 hasPublicationYear "2017" @default.
• W2769832823 type Work @default.
• W2769832823 sameAs 2769832823 @default.
• W2769832823 citedByCount "0" @default.
• W2769832823 crossrefType "proceedings-article" @default.
• W2769832823 hasAuthorship W2769832823A5008607732 @default.
• W2769832823 hasAuthorship W2769832823A5013117957 @default.
• W2769832823 hasAuthorship W2769832823A5018938467 @default.
• W2769832823 hasAuthorship W2769832823A5022826906 @default.
• W2769832823 hasAuthorship W2769832823A5032741507 @default.
• W2769832823 hasAuthorship W2769832823A5034919407 @default.
• W2769832823 hasAuthorship W2769832823A5046005276 @default.
• W2769832823 hasAuthorship W2769832823A5046351592 @default.
• W2769832823 hasAuthorship W2769832823A5048777602 @default.
• W2769832823 hasAuthorship W2769832823A5051552019 @default.
• W2769832823 hasAuthorship W2769832823A5060830413 @default.
• W2769832823 hasAuthorship W2769832823A5062276392 @default.
• W2769832823 hasAuthorship W2769832823A5067694107 @default.
• W2769832823 hasAuthorship W2769832823A5082629342 @default.
• W2769832823 hasBestOaLocation W27698328231 @default.
• W2769832823 hasConcept C126322002 @default.
• W2769832823 hasConcept C127413603 @default.
• W2769832823 hasConcept C156957248 @default.
• W2769832823 hasConcept C177713679 @default.
• W2769832823 hasConcept C1862650 @default.
• W2769832823 hasConcept C194828623 @default.
• W2769832823 hasConcept C200457457 @default.
• W2769832823 hasConcept C2776888751 @default.
• W2769832823 hasConcept C2777080012 @default.
• W2769832823 hasConcept C2777257755 @default.
• W2769832823 hasConcept C2779974597 @default.
• W2769832823 hasConcept C2987404301 @default.
• W2769832823 hasConcept C42219234 @default.
• W2769832823 hasConcept C534529494 @default.
• W2769832823 hasConcept C535046627 @default.
• W2769832823 hasConcept C71924100 @default.
• W2769832823 hasConcept C78519656 @default.
• W2769832823 hasConceptScore W2769832823C126322002 @default.
• W2769832823 hasConceptScore W2769832823C127413603 @default.
• W2769832823 hasConceptScore W2769832823C156957248 @default.
• W2769832823 hasConceptScore W2769832823C177713679 @default.
• W2769832823 hasConceptScore W2769832823C1862650 @default.
• W2769832823 hasConceptScore W2769832823C194828623 @default.
• W2769832823 hasConceptScore W2769832823C200457457 @default.
• W2769832823 hasConceptScore W2769832823C2776888751 @default.
• W2769832823 hasConceptScore W2769832823C2777080012 @default.
• W2769832823 hasConceptScore W2769832823C2777257755 @default.
• W2769832823 hasConceptScore W2769832823C2779974597 @default.
• W2769832823 hasConceptScore W2769832823C2987404301 @default.
• W2769832823 hasConceptScore W2769832823C42219234 @default.
• W2769832823 hasConceptScore W2769832823C534529494 @default.
• W2769832823 hasConceptScore W2769832823C535046627 @default.
• W2769832823 hasConceptScore W2769832823C71924100 @default.
• W2769832823 hasConceptScore W2769832823C78519656 @default.
• W2769832823 hasLocation W27698328231 @default.
• W2769832823 hasOpenAccess W2769832823 @default.
• W2769832823 hasPrimaryLocation W27698328231 @default.
• W2769832823 hasRelatedWork W1972716844 @default.
• W2769832823 hasRelatedWork W2003048313 @default.
• W2769832823 hasRelatedWork W2062800007 @default.
• W2769832823 hasRelatedWork W2065440635 @default.
• W2769832823 hasRelatedWork W2115825118 @default.
• W2769832823 hasRelatedWork W2231251879 @default.
• W2769832823 hasRelatedWork W2329893994 @default.
• W2769832823 hasRelatedWork W2485759373 @default.
• W2769832823 hasRelatedWork W2517981144 @default.
• W2769832823 hasRelatedWork W2586614032 @default.
• W2769832823 hasRelatedWork W2586757620 @default.
• W2769832823 hasRelatedWork W2765359436 @default.
• W2769832823 hasRelatedWork W2898271123 @default.
• W2769832823 hasRelatedWork W2995184692 @default.
• W2769832823 hasRelatedWork W2997212971 @default.
• W2769832823 hasRelatedWork W3028947045 @default.
• W2769832823 hasRelatedWork W3029216558 @default.
• W2769832823 hasRelatedWork W3087271074 @default.
• W2769832823 hasRelatedWork W3131045472 @default.
• W2769832823 hasRelatedWork W3185602822 @default.
• W2769832823 isParatext "false" @default.
• W2769832823 isRetracted "false" @default.
• W2769832823 magId "2769832823" @default.

• next