Matches in SemOpenAlex for { <https://semopenalex.org/work/W2769887579> ?p ?o ?g. }
- W2769887579 endingPage "382" @default.
- W2769887579 startingPage "375" @default.
- W2769887579 abstract "We report the synthesis of a biodegradable liposome gold nanoparticles for curcumin (Au-Lipos Cur NPs) delivery. This entrapped curcumin served as an in situ adjuvant for photothermal therapy. Curcumin was loaded in Au-Lipos NPs with an encapsulation efficiency of ∼70%. The gold coating enabled the NPs to specifically absorb NIR light (780nm) by virtue of Surface Plasmon Resonance (SPR) and this light energy was converted to heat. The generated heat destabilized the liposomal core enhancing the release of encapsulated curcumin. Photothermal transduction efficacy of Au-Lipos NPs (loaded with curcumin) showed a significant temperature rise upon laser irradiation causing irreversible cellular damage. In vitro photothermal effect and intracellular uptake was evaluated in B16 F10 (melanoma) cell line. Au-Lipos Cur NPs showed significantly enhanced uptake when compared with free curcumin. Enhancement in cancer cell cytotoxicity was observed in Au-Lipos Cur NPs treated group upon laser irradiation owing to curcumin. Our findings indicate that curcumin could serve as a potential in situ adjuvant for photothermal therapy of melanoma." @default.
- W2769887579 created "2017-12-04" @default.
- W2769887579 creator A5037362936 @default.
- W2769887579 creator A5039671118 @default.
- W2769887579 creator A5061487300 @default.
- W2769887579 creator A5065894578 @default.
- W2769887579 creator A5073023706 @default.
- W2769887579 creator A5076725351 @default.
- W2769887579 creator A5078017471 @default.
- W2769887579 date "2018-04-01" @default.
- W2769887579 modified "2023-10-10" @default.
- W2769887579 title "NIR triggered liposome gold nanoparticles entrapping curcumin as in situ adjuvant for photothermal treatment of skin cancer" @default.
- W2769887579 cites W1749145259 @default.
- W2769887579 cites W1969196310 @default.
- W2769887579 cites W1972044803 @default.
- W2769887579 cites W1976194786 @default.
- W2769887579 cites W1982262593 @default.
- W2769887579 cites W2002499331 @default.
- W2769887579 cites W2025635593 @default.
- W2769887579 cites W2036709321 @default.
- W2769887579 cites W2037829773 @default.
- W2769887579 cites W2042237966 @default.
- W2769887579 cites W2044556648 @default.
- W2769887579 cites W2050271125 @default.
- W2769887579 cites W2060688810 @default.
- W2769887579 cites W2066165709 @default.
- W2769887579 cites W2069119383 @default.
- W2769887579 cites W2069978879 @default.
- W2769887579 cites W2072175441 @default.
- W2769887579 cites W2077191472 @default.
- W2769887579 cites W2087997669 @default.
- W2769887579 cites W2088242076 @default.
- W2769887579 cites W2088257905 @default.
- W2769887579 cites W2096431428 @default.
- W2769887579 cites W2099007176 @default.
- W2769887579 cites W2103194980 @default.
- W2769887579 cites W2109933094 @default.
- W2769887579 cites W2115586774 @default.
- W2769887579 cites W2131935157 @default.
- W2769887579 cites W2322842178 @default.
- W2769887579 cites W2336979913 @default.
- W2769887579 cites W2559748264 @default.
- W2769887579 cites W2585158706 @default.
- W2769887579 doi "https://doi.org/10.1016/j.ijbiomac.2017.11.163" @default.
- W2769887579 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29195800" @default.
- W2769887579 hasPublicationYear "2018" @default.
- W2769887579 type Work @default.
- W2769887579 sameAs 2769887579 @default.
- W2769887579 citedByCount "78" @default.
- W2769887579 countsByYear W27698875792018 @default.
- W2769887579 countsByYear W27698875792019 @default.
- W2769887579 countsByYear W27698875792020 @default.
- W2769887579 countsByYear W27698875792021 @default.
- W2769887579 countsByYear W27698875792022 @default.
- W2769887579 countsByYear W27698875792023 @default.
- W2769887579 crossrefType "journal-article" @default.
- W2769887579 hasAuthorship W2769887579A5037362936 @default.
- W2769887579 hasAuthorship W2769887579A5039671118 @default.
- W2769887579 hasAuthorship W2769887579A5061487300 @default.
- W2769887579 hasAuthorship W2769887579A5065894578 @default.
- W2769887579 hasAuthorship W2769887579A5073023706 @default.
- W2769887579 hasAuthorship W2769887579A5076725351 @default.
- W2769887579 hasAuthorship W2769887579A5078017471 @default.
- W2769887579 hasConcept C104819515 @default.
- W2769887579 hasConcept C106847996 @default.
- W2769887579 hasConcept C12554922 @default.
- W2769887579 hasConcept C155672457 @default.
- W2769887579 hasConcept C171250308 @default.
- W2769887579 hasConcept C182606246 @default.
- W2769887579 hasConcept C185154212 @default.
- W2769887579 hasConcept C185592680 @default.
- W2769887579 hasConcept C192562407 @default.
- W2769887579 hasConcept C2777742735 @default.
- W2769887579 hasConcept C2778250585 @default.
- W2769887579 hasConcept C55493867 @default.
- W2769887579 hasConcept C86803240 @default.
- W2769887579 hasConceptScore W2769887579C104819515 @default.
- W2769887579 hasConceptScore W2769887579C106847996 @default.
- W2769887579 hasConceptScore W2769887579C12554922 @default.
- W2769887579 hasConceptScore W2769887579C155672457 @default.
- W2769887579 hasConceptScore W2769887579C171250308 @default.
- W2769887579 hasConceptScore W2769887579C182606246 @default.
- W2769887579 hasConceptScore W2769887579C185154212 @default.
- W2769887579 hasConceptScore W2769887579C185592680 @default.
- W2769887579 hasConceptScore W2769887579C192562407 @default.
- W2769887579 hasConceptScore W2769887579C2777742735 @default.
- W2769887579 hasConceptScore W2769887579C2778250585 @default.
- W2769887579 hasConceptScore W2769887579C55493867 @default.
- W2769887579 hasConceptScore W2769887579C86803240 @default.
- W2769887579 hasLocation W27698875791 @default.
- W2769887579 hasLocation W27698875792 @default.
- W2769887579 hasOpenAccess W2769887579 @default.
- W2769887579 hasPrimaryLocation W27698875791 @default.
- W2769887579 hasRelatedWork W1582853635 @default.
- W2769887579 hasRelatedWork W1888163363 @default.
- W2769887579 hasRelatedWork W1982563407 @default.
- W2769887579 hasRelatedWork W2080766552 @default.
- W2769887579 hasRelatedWork W2324404998 @default.