FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2770078552> ?p ?o ?g. }

• W2770078552 endingPage "421" @default.
• W2770078552 startingPage "415" @default.
• W2770078552 abstract "Abstract Background Spread hepatic tumours are not suitable for treatment either by surgery or conventional ablation methods. The aim of this study was to evaluate feasibility and safety of selectively increasing the healthy hepatic conductivity by the hypersaline infusion (HI) through the portal vein. We hypothesize this will allow simultaneous safe treatment of all nodules by irreversible electroporation (IRE) when applied in a transhepatic fashion. Material and methods Sprague Dawley (Group A, n = 10) and Athymic rats with implanted hepatic tumour (Group B, n = 8) were employed. HI was performed (NaCl 20%, 3.8 mL/Kg) by trans-splenic puncture. Deionized serum (40 mL/Kg) and furosemide (2 mL/Kg) were simultaneously infused through the jugular vein to compensate hypernatremia. Changes in conductivity were monitored in the hepatic and tumour tissue. The period in which hepatic conductivity was higher than tumour conductivity was defined as the therapeutic window (TW). Animals were monitored during 1-month follow-up. The animals were sacrificed and selective samples were used for histological analysis. Results The overall survival rate was 82.4% after the HI protocol. The mean maximum hepatic conductivity after HI was 2.7 and 3.5 times higher than the baseline value, in group A and B, respectively. The mean maximum hepatic conductivity after HI was 1.4 times higher than tumour tissue in group B creating a TW to implement selective IRE. Conclusions HI through the portal vein is safe when the hypersaline overload is compensated with deionized serum and it may provide a TW for focused IRE treatment on tumour nodules." @default.
• W2770078552 created "2017-12-04" @default.
• W2770078552 creator A5000067052 @default.
• W2770078552 creator A5004386682 @default.
• W2770078552 creator A5019940206 @default.
• W2770078552 creator A5023616686 @default.
• W2770078552 creator A5024503767 @default.
• W2770078552 creator A5033699618 @default.
• W2770078552 creator A5041758017 @default.
• W2770078552 creator A5050985305 @default.
• W2770078552 creator A5051681898 @default.
• W2770078552 creator A5066235760 @default.
• W2770078552 creator A5080923851 @default.
• W2770078552 creator A5090952033 @default.
• W2770078552 date "2017-11-29" @default.
• W2770078552 modified "2023-10-08" @default.
• W2770078552 title "Focused transhepatic electroporation mediated by hypersaline infusion through the portal vein in rat model. Preliminary results on differential conductivity" @default.
• W2770078552 cites W163155618 @default.
• W2770078552 cites W1884663465 @default.
• W2770078552 cites W1967920937 @default.
• W2770078552 cites W1970400562 @default.
• W2770078552 cites W1979538248 @default.
• W2770078552 cites W1979933511 @default.
• W2770078552 cites W1985734647 @default.
• W2770078552 cites W1990736148 @default.
• W2770078552 cites W1995583440 @default.
• W2770078552 cites W2002314594 @default.
• W2770078552 cites W2005288489 @default.
• W2770078552 cites W2007345685 @default.
• W2770078552 cites W2017169826 @default.
• W2770078552 cites W2026761507 @default.
• W2770078552 cites W2051865270 @default.
• W2770078552 cites W2061356186 @default.
• W2770078552 cites W2083043482 @default.
• W2770078552 cites W2104248047 @default.
• W2770078552 cites W2129670488 @default.
• W2770078552 cites W2149476799 @default.
• W2770078552 cites W2160594924 @default.
• W2770078552 cites W2163517119 @default.
• W2770078552 cites W2202989786 @default.
• W2770078552 cites W2318559711 @default.
• W2770078552 cites W2462520017 @default.
• W2770078552 cites W2579205376 @default.
• W2770078552 cites W2583626505 @default.
• W2770078552 cites W2599815497 @default.
• W2770078552 cites W2618223503 @default.
• W2770078552 cites W294183269 @default.
• W2770078552 cites W4254021855 @default.
• W2770078552 doi "https://doi.org/10.1515/raon-2017-0051" @default.
• W2770078552 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5765318" @default.
• W2770078552 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29333120" @default.
• W2770078552 hasPublicationYear "2017" @default.
• W2770078552 type Work @default.
• W2770078552 sameAs 2770078552 @default.
• W2770078552 citedByCount "3" @default.
• W2770078552 countsByYear W27700785522019 @default.
• W2770078552 countsByYear W27700785522021 @default.
• W2770078552 countsByYear W27700785522023 @default.
• W2770078552 crossrefType "journal-article" @default.
• W2770078552 hasAuthorship W2770078552A5000067052 @default.
• W2770078552 hasAuthorship W2770078552A5004386682 @default.
• W2770078552 hasAuthorship W2770078552A5019940206 @default.
• W2770078552 hasAuthorship W2770078552A5023616686 @default.
• W2770078552 hasAuthorship W2770078552A5024503767 @default.
• W2770078552 hasAuthorship W2770078552A5033699618 @default.
• W2770078552 hasAuthorship W2770078552A5041758017 @default.
• W2770078552 hasAuthorship W2770078552A5050985305 @default.
• W2770078552 hasAuthorship W2770078552A5051681898 @default.
• W2770078552 hasAuthorship W2770078552A5066235760 @default.
• W2770078552 hasAuthorship W2770078552A5080923851 @default.
• W2770078552 hasAuthorship W2770078552A5090952033 @default.
• W2770078552 hasBestOaLocation W27700785521 @default.
• W2770078552 hasConcept C104317684 @default.
• W2770078552 hasConcept C126322002 @default.
• W2770078552 hasConcept C126894567 @default.
• W2770078552 hasConcept C141071460 @default.
• W2770078552 hasConcept C185592680 @default.
• W2770078552 hasConcept C186852380 @default.
• W2770078552 hasConcept C2777202286 @default.
• W2770078552 hasConcept C2777955127 @default.
• W2770078552 hasConcept C2778716261 @default.
• W2770078552 hasConcept C2778902805 @default.
• W2770078552 hasConcept C2779033008 @default.
• W2770078552 hasConcept C2910727132 @default.
• W2770078552 hasConcept C42219234 @default.
• W2770078552 hasConcept C55493867 @default.
• W2770078552 hasConcept C71924100 @default.
• W2770078552 hasConcept C90924648 @default.
• W2770078552 hasConceptScore W2770078552C104317684 @default.
• W2770078552 hasConceptScore W2770078552C126322002 @default.
• W2770078552 hasConceptScore W2770078552C126894567 @default.
• W2770078552 hasConceptScore W2770078552C141071460 @default.
• W2770078552 hasConceptScore W2770078552C185592680 @default.
• W2770078552 hasConceptScore W2770078552C186852380 @default.
• W2770078552 hasConceptScore W2770078552C2777202286 @default.
• W2770078552 hasConceptScore W2770078552C2777955127 @default.
• W2770078552 hasConceptScore W2770078552C2778716261 @default.
• W2770078552 hasConceptScore W2770078552C2778902805 @default.

• next