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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2770239749> ?p ?o ?g. }

• W2770239749 abstract "The oscillation of microbubbles has long been hypothesized to provide the opportunity to enhance gene delivery as a result of changes in membrane permeability; however, translationally-relevant therapeutic protocols have not yet been realized. We sought to develop and validate a protocol to transfect endogenous mesenchymal stem cells (MSCs) via the local injection of plasmids and microbubbles and the application of ultrasound. We apply this therapy in a pre-clinical model to solve an important clinical problem — that of healing segmental bone defects. More than two million bone-grafting procedures are performed each year using autografts or allografts and these standard of care therapies have substantial disadvantages." @default.
• W2770239749 created "2017-12-04" @default.
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• W2770239749 date "2017-09-01" @default.
• W2770239749 modified "2023-09-23" @default.
• W2770239749 title "Notice of Removal: Ultrasound-mediated transfection of endogenous stem cells for regenerative medicine" @default.
• W2770239749 doi "https://doi.org/10.1109/ultsym.2017.8092153" @default.
• W2770239749 hasPublicationYear "2017" @default.
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