FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2770298921> ?p ?o ?g. }

• W2770298921 endingPage "S1025" @default.
• W2770298921 startingPage "S1024" @default.
• W2770298921 abstract "Epithelioid hemangioendothelioma (EHE) of lung and pleura are rare vascular neoplasm with an epithelioid and histiocytoid appearance that originated from vascular endothelial cells. Pulmonary EHE was first described as “intravascular bronchioloalveolar tumor” (IVBAT) by Dail et al. in 1975, since it was believed to be an aggressive form of bronchoalveolar cell carcinoma with propensity to invade adjacent blood vessels. It is described by the World Health Organization 2002 classification as lesion locally aggressive with metastatic potential, a neoplasm of low to intermediate-grade malignancy. It occurs with a predilection for younger (mean age 39) female (60% of cases). Most patient are asymptomatic (50%) although dyspnea, cough, chest pain, hemoptysis can occur. By immunohistochemistry, EHE shows the typical markers of vascular differentiation. Primary epithelioid hemangioendotheliomas of pleura are extremely rare, usually affecting males, and associated with a variety of clinical manifestations and poor prognosis. We present a rare case of EHE with an extensive pleuro-pulmonary involvement. A 50-year old non-smoking woman presented to our institution complaining of persistent cough and progressive dyspnea first treated with antibiotics without improvement of the symptoms. Chest computed tomography (CT) showed multiple disseminated nodules of both lungs mostly involving the upper lobes with associated right-sided pleural effusion and thickening. There is a elevated serum level of Cancer Antigen (CA) 125. In a right triportal video-assisted thoracoscopy surgery (VATS) we performed wedge resections of the right upper, middle and lower lobes with diffuse nodular process and multiple biopsies of thickened pleura. Pathological examination of the pleuro-pulmonary samples showed multiple, diffuse nodular infiltrates of epithelioid cells with frequent cytoplasmic vacuoles, rare mitoses and foci of tumor necrosis. Immunohistochemistry was positive for Vimentin, CD31, CD34, ETS-related gene (ERG). Therefore, a final diagnosis of Epithelioid hemangioendothelioma was made on the basis of the radiographic, cytomorphologic, and immunohistochemical findings. Pulmonary Epithelioid hemangioendothelioma is a vascular tumor with low to intermediate-grade malignancy. Pleural epithelioid hemangioendothelioma is less common and the clinical behavior is more aggressive and has a poorer prognosis. Our case is an epithelioid hemangioendothelioma with a clinical and pathologic pleuro-pulmonary involvement and a very aggressive clinical course." @default.
• W2770298921 created "2017-12-04" @default.
• W2770298921 creator A5018009823 @default.
• W2770298921 creator A5060451406 @default.
• W2770298921 creator A5085355026 @default.
• W2770298921 creator A5087354402 @default.
• W2770298921 creator A5087748881 @default.
• W2770298921 creator A5089913169 @default.
• W2770298921 date "2017-01-01" @default.
• W2770298921 modified "2023-09-27" @default.
• W2770298921 title "P2.04-046 A Rare Case of Pleuro-Pulmonary Epitheliod Hemangioendothelioma" @default.
• W2770298921 doi "https://doi.org/10.1016/j.jtho.2016.11.1426" @default.
• W2770298921 hasPublicationYear "2017" @default.
• W2770298921 type Work @default.
• W2770298921 sameAs 2770298921 @default.
• W2770298921 citedByCount "0" @default.
• W2770298921 crossrefType "journal-article" @default.
• W2770298921 hasAuthorship W2770298921A5018009823 @default.
• W2770298921 hasAuthorship W2770298921A5060451406 @default.
• W2770298921 hasAuthorship W2770298921A5085355026 @default.
• W2770298921 hasAuthorship W2770298921A5087354402 @default.
• W2770298921 hasAuthorship W2770298921A5087748881 @default.
• W2770298921 hasAuthorship W2770298921A5089913169 @default.
• W2770298921 hasBestOaLocation W27702989211 @default.
• W2770298921 hasConcept C126322002 @default.
• W2770298921 hasConcept C126838900 @default.
• W2770298921 hasConcept C142724271 @default.
• W2770298921 hasConcept C204232928 @default.
• W2770298921 hasConcept C2776256026 @default.
• W2770298921 hasConcept C2777714996 @default.
• W2770298921 hasConcept C2779399171 @default.
• W2770298921 hasConcept C2779634585 @default.
• W2770298921 hasConcept C2780685469 @default.
• W2770298921 hasConcept C71924100 @default.
• W2770298921 hasConceptScore W2770298921C126322002 @default.
• W2770298921 hasConceptScore W2770298921C126838900 @default.
• W2770298921 hasConceptScore W2770298921C142724271 @default.
• W2770298921 hasConceptScore W2770298921C204232928 @default.
• W2770298921 hasConceptScore W2770298921C2776256026 @default.
• W2770298921 hasConceptScore W2770298921C2777714996 @default.
• W2770298921 hasConceptScore W2770298921C2779399171 @default.
• W2770298921 hasConceptScore W2770298921C2779634585 @default.
• W2770298921 hasConceptScore W2770298921C2780685469 @default.
• W2770298921 hasConceptScore W2770298921C71924100 @default.
• W2770298921 hasIssue "1" @default.
• W2770298921 hasLocation W27702989211 @default.
• W2770298921 hasOpenAccess W2770298921 @default.
• W2770298921 hasPrimaryLocation W27702989211 @default.
• W2770298921 hasRelatedWork W1514650927 @default.
• W2770298921 hasRelatedWork W1841185769 @default.
• W2770298921 hasRelatedWork W2274053957 @default.
• W2770298921 hasRelatedWork W2337536374 @default.
• W2770298921 hasRelatedWork W2352157767 @default.
• W2770298921 hasRelatedWork W2591994030 @default.
• W2770298921 hasRelatedWork W2902148150 @default.
• W2770298921 hasRelatedWork W2986254459 @default.
• W2770298921 hasRelatedWork W4246373120 @default.
• W2770298921 hasRelatedWork W4319592828 @default.
• W2770298921 hasVolume "12" @default.
• W2770298921 isParatext "false" @default.
• W2770298921 isRetracted "false" @default.
• W2770298921 magId "2770298921" @default.
• W2770298921 workType "article" @default.